EP3126027A4 - Devices and methods for purification, detection and use of biological cells - Google Patents

Devices and methods for purification, detection and use of biological cells Download PDF

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Publication number
EP3126027A4
EP3126027A4 EP15773853.5A EP15773853A EP3126027A4 EP 3126027 A4 EP3126027 A4 EP 3126027A4 EP 15773853 A EP15773853 A EP 15773853A EP 3126027 A4 EP3126027 A4 EP 3126027A4
Authority
EP
European Patent Office
Prior art keywords
purification
detection
methods
devices
biological cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15773853.5A
Other languages
German (de)
French (fr)
Other versions
EP3126027A1 (en
Inventor
Douglas T. Gjerde
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP3126027A1 publication Critical patent/EP3126027A1/en
Publication of EP3126027A4 publication Critical patent/EP3126027A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/428—Frontal mode
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B01D15/166—Fluid composition conditioning, e.g. gradient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/422—Displacement mode
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP15773853.5A 2014-04-03 2015-04-03 Devices and methods for purification, detection and use of biological cells Withdrawn EP3126027A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461974950P 2014-04-03 2014-04-03
US201462061636P 2014-10-08 2014-10-08
PCT/US2015/024374 WO2015154048A1 (en) 2014-04-03 2015-04-03 Devices and methods for purification, detection and use of biological cells

Publications (2)

Publication Number Publication Date
EP3126027A1 EP3126027A1 (en) 2017-02-08
EP3126027A4 true EP3126027A4 (en) 2017-11-01

Family

ID=54241352

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15773853.5A Withdrawn EP3126027A4 (en) 2014-04-03 2015-04-03 Devices and methods for purification, detection and use of biological cells

Country Status (3)

Country Link
EP (1) EP3126027A4 (en)
GB (2) GB2587768B (en)
WO (1) WO2015154048A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201521784D0 (en) * 2015-12-10 2016-01-27 Univ Birmingham Cell purification
EP3863763A4 (en) * 2018-10-09 2022-10-19 C Technologies, Inc. Mass control system for chromatography

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773224A (en) * 1996-02-12 1998-06-30 Grandics; Peter Immunoselection system for cell elution
WO2014127314A1 (en) * 2013-02-15 2014-08-21 Phynexus, Inc. Devices and methods for purification of biological cells

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215927A (en) * 1986-01-30 1993-06-01 Fred Hutchinson Cancer Research Center Method for immunoselection of cells using avidin and biotin
AU1944699A (en) * 1997-12-23 1999-07-12 Vicam, L.P. Generic signalling mechanism for detection of analytes
JP2006511807A (en) * 2002-12-18 2006-04-06 アクララ バイオサイエンシーズ， インコーポレイテッド Multiplex immunohistochemical assay using molecular tags
US8377715B2 (en) * 2003-07-14 2013-02-19 Phynexus, Inc. Method and device for sample preparation
US20090081084A1 (en) * 2003-07-14 2009-03-26 Gjerde Douglas T Low Dead Volume Extraction Column Device
US20100140173A1 (en) * 2004-12-03 2010-06-10 Chris Suh Method and Device for Gravity Flow Chromatography
US9370732B2 (en) * 2013-02-15 2016-06-21 Douglas T. Gjerde Methods for purifying biological cells
CN106940268B (en) * 2012-02-23 2021-09-21 朱诺治疗有限公司 Chromatographic separation of cells and other complex biological materials
JP6445429B2 (en) * 2012-06-27 2018-12-26 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Method and use thereof for selecting and generating tailor-made selective and multispecific therapeutic molecules comprising at least two different targeting entities

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773224A (en) * 1996-02-12 1998-06-30 Grandics; Peter Immunoselection system for cell elution
WO2014127314A1 (en) * 2013-02-15 2014-08-21 Phynexus, Inc. Devices and methods for purification of biological cells

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LI CUIQIN ET AL: "Establishment of the model of white blood cell membrane chromatography and screening of antagonizing TLR4receptor component fromAtractylodes macrocephalaKoidz", SCIENCE IN CHINA. SERIE C: LIFE SCIENCE, GORDON AND BREACH, AMSTERDAM, NL, vol. 49, no. 2, 25 March 2006 (2006-03-25), pages 182 - 189, XP035977382, ISSN: 1006-9305, [retrieved on 20060325], DOI: 10.1007/S11427-006-0182-7 *
See also references of WO2015154048A1 *

Also Published As

Publication number Publication date
GB2587768A (en) 2021-04-07
GB2587768B (en) 2021-08-18
WO2015154048A1 (en) 2015-10-08
GB201618356D0 (en) 2016-12-14
GB2539857A (en) 2016-12-28
GB2539857B (en) 2021-03-31
GB202102155D0 (en) 2021-03-31
EP3126027A1 (en) 2017-02-08

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