SG10201510086VA - Drug selection for malignant cancer therapy using antibody-based arrays - Google Patents
Drug selection for malignant cancer therapy using antibody-based arraysInfo
- Publication number
- SG10201510086VA SG10201510086VA SG10201510086VA SG10201510086VA SG10201510086VA SG 10201510086V A SG10201510086V A SG 10201510086VA SG 10201510086V A SG10201510086V A SG 10201510086VA SG 10201510086V A SG10201510086V A SG 10201510086VA SG 10201510086V A SG10201510086V A SG 10201510086VA
- Authority
- SG
- Singapore
- Prior art keywords
- antibody
- cancer therapy
- drug selection
- malignant cancer
- based arrays
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061426948P | 2010-12-23 | 2010-12-23 | |
| US201161438904P | 2011-02-02 | 2011-02-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201510086VA true SG10201510086VA (en) | 2016-01-28 |
Family
ID=45464137
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013046925A SG191230A1 (en) | 2010-12-23 | 2011-12-21 | Drug selection for malignant cancer therapy using antibody-based arrays |
| SG10201510086VA SG10201510086VA (en) | 2010-12-23 | 2011-12-21 | Drug selection for malignant cancer therapy using antibody-based arrays |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013046925A SG191230A1 (en) | 2010-12-23 | 2011-12-21 | Drug selection for malignant cancer therapy using antibody-based arrays |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20140024548A1 (zh) |
| EP (1) | EP2656077A1 (zh) |
| JP (1) | JP2014503821A (zh) |
| KR (1) | KR20140002711A (zh) |
| CN (1) | CN103384828A (zh) |
| AU (1) | AU2011348256A1 (zh) |
| CA (1) | CA2822283A1 (zh) |
| IL (1) | IL227009B (zh) |
| MX (1) | MX2013007429A (zh) |
| NZ (1) | NZ612483A (zh) |
| SG (2) | SG191230A1 (zh) |
| WO (1) | WO2012088337A1 (zh) |
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| WO2009137807A2 (en) | 2008-05-08 | 2009-11-12 | Asuragen, Inc. | Compositions and methods related to mirna modulation of neovascularization or angiogenesis |
| CN110544517A (zh) | 2011-05-10 | 2019-12-06 | 雀巢产品有限公司 | 用于个体化治疗管理的疾病活动性表征方法 |
| WO2013086031A1 (en) * | 2011-12-05 | 2013-06-13 | Nestec S.A. | Method of therapy selection for patients with cancer |
| CA2887035A1 (en) | 2012-10-05 | 2014-04-10 | Nestec S.A. | Methods for predicting and monitoring mucosal healing |
| RS58147B1 (sr) * | 2012-12-21 | 2019-02-28 | Janssen Biotech Inc | Senzitivni višestruki imunotest za rastvorljive receptore faktora rasta fibroblasta |
| WO2014122600A1 (en) | 2013-02-05 | 2014-08-14 | Nestec S.A. | Methods of selecting combination therapy for colorectal cancer patients |
| EP2954068B8 (en) * | 2013-02-05 | 2018-10-31 | Pierian Holdings, Inc. | Drug selection for non-small cell lung cancer therapy |
| US10273211B2 (en) * | 2013-03-15 | 2019-04-30 | Exelixis, Inc. | Metabolites of N-{4-([6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
| EP3033434A2 (en) * | 2013-08-14 | 2016-06-22 | Qiagen Mansfield, Inc. | Compositions and methods for multimodal analysis of cmet nucleic acids |
| WO2015110989A1 (en) | 2014-01-23 | 2015-07-30 | Nestec S.A. | Biomarker panel for assessment of mucosal healing |
| KR102338678B1 (ko) * | 2014-04-03 | 2021-12-13 | 삼성전자주식회사 | 항 c-Met 항체 효과 예측을 위한 바이오마커 |
| EP2937421B1 (en) | 2014-04-03 | 2018-10-24 | Samsung Electronics Co., Ltd | Biomarker for predicting effect of an anti-C-met antibody |
| KR20160024639A (ko) | 2014-08-26 | 2016-03-07 | 삼성전자주식회사 | c-Met 표적 치료제의 저항성 또는 효능 예측을 위한 바이오마커 PDGF |
| EP3210016A1 (en) | 2014-10-20 | 2017-08-30 | Nestec S.A. | Methods for prediction of anti-tnf alpha drug levels and autoantibody formation |
| WO2016081773A2 (en) * | 2014-11-19 | 2016-05-26 | Mirna Therapeutics, Inc. | Combination cancer therapy with c-met inhibitors and synthetic oligonucleotides |
| CN105891496A (zh) * | 2014-12-09 | 2016-08-24 | 上海华盈生物医药科技有限公司 | 酪氨酸激酶抑制剂类靶向用药指导抗体芯片和检测方法 |
| WO2016196774A1 (en) * | 2015-06-03 | 2016-12-08 | Aelan Cell Technologies, Inc. | Methods and devices for the production and delivery of beneficial factors from stem cells |
| US11274348B2 (en) * | 2016-06-03 | 2022-03-15 | Singapore Health Services Pte Ltd | Use of biomarkers in determining susceptibility to disease treatment |
| KR20180046256A (ko) * | 2016-10-27 | 2018-05-08 | 삼성전자주식회사 | c-Met 저해제의 효능 예측을 위한 바이오마커 HGF |
| CA3135012A1 (en) | 2017-05-31 | 2018-12-06 | Anjali Jain | Methods for assessing mucosal healing in crohn's disease patients |
| JP7007761B2 (ja) * | 2017-09-18 | 2022-03-04 | 国立台湾大学 | 甲状腺癌の予後のためのバイオマーカー |
| CN116597893B (zh) * | 2023-06-14 | 2023-12-15 | 北京金匙医学检验实验室有限公司 | 预测耐药基因-病原微生物归属的方法 |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
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| US5532138A (en) | 1990-04-26 | 1996-07-02 | Behringwerke Ag | Method and kits for determining peroxidatively active catalysts |
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| US5571894A (en) | 1991-02-05 | 1996-11-05 | Ciba-Geigy Corporation | Recombinant antibodies specific for a growth factor receptor |
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| WO1993008829A1 (en) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions that mediate killing of hiv-infected cells |
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| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
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| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
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| WO2011008990A1 (en) * | 2009-07-15 | 2011-01-20 | Prometheus Laboratories Inc. | Drug selection for gastric cancer therapy using antibody-based arrays |
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| RU2519647C2 (ru) * | 2007-07-13 | 2014-06-20 | Нестек С.А. | Выбор лекарственных средств для терапии рака легких с помощью матриц на основе антител |
| CA2923248A1 (en) | 2008-02-25 | 2009-09-03 | Nestec S.A. | Methods for detecting truncated receptors |
| TW200942552A (en) * | 2008-03-06 | 2009-10-16 | Genentech Inc | Combination therapy with c-Met and HER antagonists |
| UY31800A (es) * | 2008-05-05 | 2009-11-10 | Smithkline Beckman Corp | Metodo de tratamiento de cancer usando un inhibidor de cmet y axl y un inhibidor de erbb |
| US8301258B2 (en) | 2008-08-14 | 2012-10-30 | The Chinese University Of Hong Kong | Methods and devices for preventing ankle sprain injuries |
| CN101836991B (zh) * | 2009-03-19 | 2013-05-22 | 鼎泓国际投资（香港）有限公司 | 含有索拉非尼、cMet抑制剂与EGFR酪氨酸激酶抑制剂的药物组合物及其应用 |
| CN101837129B (zh) * | 2009-03-19 | 2012-12-12 | 鼎泓国际投资（香港）有限公司 | 含cMet抑制剂、HDAC抑制剂与EGFR酪氨酸激酶抑制剂的药物组合物及其应用 |
| CA2761777A1 (en) | 2009-05-14 | 2010-11-18 | Prometheus Laboratories Inc. | Biomarkers for determining sensitivity of breast cancer cells to her2-targeted therapy |
| JP5819307B2 (ja) | 2009-10-20 | 2015-11-24 | ネステク ソシエテ アノニム | 発癌性融合タンパク質を検出するための近接媒介性アッセイ |
| WO2014122600A1 (en) * | 2013-02-05 | 2014-08-14 | Nestec S.A. | Methods of selecting combination therapy for colorectal cancer patients |
-
2011
- 2011-12-21 CA CA2822283A patent/CA2822283A1/en not_active Abandoned
- 2011-12-21 WO PCT/US2011/066624 patent/WO2012088337A1/en active Application Filing
- 2011-12-21 NZ NZ61248311A patent/NZ612483A/en not_active IP Right Cessation
- 2011-12-21 SG SG2013046925A patent/SG191230A1/en unknown
- 2011-12-21 MX MX2013007429A patent/MX2013007429A/es unknown
- 2011-12-21 CN CN2011800682698A patent/CN103384828A/zh active Pending
- 2011-12-21 EP EP11805738.9A patent/EP2656077A1/en not_active Withdrawn
- 2011-12-21 AU AU2011348256A patent/AU2011348256A1/en not_active Abandoned
- 2011-12-21 SG SG10201510086VA patent/SG10201510086VA/en unknown
- 2011-12-21 JP JP2013546392A patent/JP2014503821A/ja active Pending
- 2011-12-21 KR KR1020137019356A patent/KR20140002711A/ko not_active Application Discontinuation
-
2013
- 2013-06-17 IL IL227009A patent/IL227009B/en active IP Right Grant
- 2013-06-20 US US13/923,316 patent/US20140024548A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2656077A1 (en) | 2013-10-30 |
| JP2014503821A (ja) | 2014-02-13 |
| WO2012088337A1 (en) | 2012-06-28 |
| SG191230A1 (en) | 2013-07-31 |
| KR20140002711A (ko) | 2014-01-08 |
| AU2011348256A1 (en) | 2013-07-11 |
| CA2822283A1 (en) | 2012-06-28 |
| IL227009B (en) | 2018-03-29 |
| US20140024548A1 (en) | 2014-01-23 |
| MX2013007429A (es) | 2014-01-31 |
| NZ612483A (en) | 2015-03-27 |
| CN103384828A (zh) | 2013-11-06 |
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