SE9504019D0 - Method for production of proteins - Google Patents
Method for production of proteinsInfo
- Publication number
- SE9504019D0 SE9504019D0 SE9504019A SE9504019A SE9504019D0 SE 9504019 D0 SE9504019 D0 SE 9504019D0 SE 9504019 A SE9504019 A SE 9504019A SE 9504019 A SE9504019 A SE 9504019A SE 9504019 D0 SE9504019 D0 SE 9504019D0
- Authority
- SE
- Sweden
- Prior art keywords
- cells
- polypeptide
- proteins
- protein
- production
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 230000003196 chaotropic effect Effects 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000007865 diluting Methods 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 238000003306 harvesting Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 210000001236 prokaryotic cell Anatomy 0.000 abstract 1
- 230000003381 solubilizing effect Effects 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9504019A SE9504019D0 (sv) | 1995-11-13 | 1995-11-13 | Method for production of proteins |
JP51878397A JP3930051B2 (ja) | 1995-11-13 | 1996-11-12 | 正しく折畳まれた生物学的に活性の組換えタンパク質の製造方法 |
US09/051,941 US6605706B1 (en) | 1995-11-13 | 1996-11-12 | Method for producing a correctly folded, biological active recombinant protein |
PCT/SE1996/001456 WO1997018233A1 (en) | 1995-11-13 | 1996-11-12 | Method for producing a correctly folded, biological active recombinant protein |
DE69631906T DE69631906T2 (de) | 1995-11-13 | 1996-11-12 | Verfahren zur herstellung von richtig gefaltetem, biologisch aktivem, rekombinantem protein |
AU76596/96A AU705192B2 (en) | 1995-11-13 | 1996-11-12 | Method for producing a correctly folded, biological active recombinant protein |
EP96939406A EP0952981B1 (en) | 1995-11-13 | 1996-11-12 | Method for producing a correctly folded, biological active recombinant protein |
AT96939406T ATE261985T1 (de) | 1995-11-13 | 1996-11-12 | Verfahren zur herstellung von richtig gefaltetem, biologisch aktivem, rekombinantem protein |
CA002236751A CA2236751C (en) | 1995-11-13 | 1996-11-12 | Method for producing a correctly folded, biological active recombinant protein |
NO19982155A NO320175B1 (no) | 1995-11-13 | 1998-05-12 | Fremgangsmate for fremstilling av korrekt foldet, biologisk aktivt rekombinant protein eller polypeptid. |
HK00102454A HK1023781A1 (en) | 1995-11-13 | 2000-04-26 | Method for producing a correctly folded, biological active recombinant protein. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9504019A SE9504019D0 (sv) | 1995-11-13 | 1995-11-13 | Method for production of proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9504019D0 true SE9504019D0 (sv) | 1995-11-13 |
Family
ID=20400188
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9504019A SE9504019D0 (sv) | 1995-11-13 | 1995-11-13 | Method for production of proteins |
Country Status (11)
Country | Link |
---|---|
US (1) | US6605706B1 (sv) |
EP (1) | EP0952981B1 (sv) |
JP (1) | JP3930051B2 (sv) |
AT (1) | ATE261985T1 (sv) |
AU (1) | AU705192B2 (sv) |
CA (1) | CA2236751C (sv) |
DE (1) | DE69631906T2 (sv) |
HK (1) | HK1023781A1 (sv) |
NO (1) | NO320175B1 (sv) |
SE (1) | SE9504019D0 (sv) |
WO (1) | WO1997018233A1 (sv) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6653098B1 (en) * | 1998-02-23 | 2003-11-25 | G. D. Searle & Co. | Method of producing mouse and human endostatin |
MXPA00009564A (es) * | 1998-03-31 | 2004-03-10 | Thongua Gantech Biotechnology | Proteina quimerica que contiene una secuencia similar a la caperona intramolecular y su aplicacion a la produccion de insulina. |
GB9913437D0 (en) * | 1999-06-09 | 1999-08-11 | Medical Res Council | Fusion proteins |
FR2820424B1 (fr) * | 2001-02-05 | 2004-01-02 | Merieux Oravax | Procede de purification de alpa |
SG162834A1 (en) | 2006-07-14 | 2010-07-29 | Genentech Inc | Refolding of recombinant proteins |
US9119832B2 (en) | 2014-02-05 | 2015-09-01 | The Regents Of The University Of California | Methods of treating mild brain injury |
WO2017075535A1 (en) | 2015-10-28 | 2017-05-04 | Oxeia Biopharmaceuticals, Inc. | Methods of treating neurodegenerative conditions |
JPWO2022097216A1 (sv) * | 2020-11-05 | 2022-05-12 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8505922D0 (sv) * | 1985-12-13 | 1985-12-13 | Kabigen Ab | Construction of an igg binding protein to facilitate downstream processing using protein engineering |
US5231178A (en) | 1991-01-16 | 1993-07-27 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Method for the purification of intact, correctly-folded insulin-like growth factor-1 |
US5288931A (en) * | 1991-12-06 | 1994-02-22 | Genentech, Inc. | Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation |
DE59305396D1 (de) * | 1992-12-02 | 1997-03-20 | Hoechst Ag | Verfahren zur Gewinnung von Proinsulin mit korrekt verbundenen Cystinbrücken |
US5663304A (en) * | 1993-08-20 | 1997-09-02 | Genentech, Inc. | Refolding of misfolded insulin-like growth factor-I |
US5407810A (en) | 1993-08-20 | 1995-04-18 | Genentech, Inc. | Aqueous multiple-phase isolation of polypeptide |
-
1995
- 1995-11-13 SE SE9504019A patent/SE9504019D0/sv unknown
-
1996
- 1996-11-12 CA CA002236751A patent/CA2236751C/en not_active Expired - Fee Related
- 1996-11-12 WO PCT/SE1996/001456 patent/WO1997018233A1/en active IP Right Grant
- 1996-11-12 AT AT96939406T patent/ATE261985T1/de not_active IP Right Cessation
- 1996-11-12 US US09/051,941 patent/US6605706B1/en not_active Expired - Fee Related
- 1996-11-12 JP JP51878397A patent/JP3930051B2/ja not_active Expired - Fee Related
- 1996-11-12 DE DE69631906T patent/DE69631906T2/de not_active Expired - Fee Related
- 1996-11-12 AU AU76596/96A patent/AU705192B2/en not_active Ceased
- 1996-11-12 EP EP96939406A patent/EP0952981B1/en not_active Expired - Lifetime
-
1998
- 1998-05-12 NO NO19982155A patent/NO320175B1/no not_active IP Right Cessation
-
2000
- 2000-04-26 HK HK00102454A patent/HK1023781A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69631906T2 (de) | 2005-01-20 |
JP3930051B2 (ja) | 2007-06-13 |
ATE261985T1 (de) | 2004-04-15 |
JP2000500023A (ja) | 2000-01-11 |
EP0952981A1 (en) | 1999-11-03 |
AU7659696A (en) | 1997-06-05 |
NO320175B1 (no) | 2005-11-07 |
US6605706B1 (en) | 2003-08-12 |
WO1997018233A1 (en) | 1997-05-22 |
EP0952981B1 (en) | 2004-03-17 |
NO982155L (no) | 1998-05-12 |
AU705192B2 (en) | 1999-05-20 |
CA2236751A1 (en) | 1997-05-22 |
DE69631906D1 (de) | 2004-04-22 |
HK1023781A1 (en) | 2000-09-22 |
NO982155D0 (no) | 1998-05-12 |
CA2236751C (en) | 2007-01-09 |
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