SE8504416D0 - SYNTHESIS OF THIOGLYCOLIC ACID - Google Patents
SYNTHESIS OF THIOGLYCOLIC ACIDInfo
- Publication number
- SE8504416D0 SE8504416D0 SE8504416A SE8504416A SE8504416D0 SE 8504416 D0 SE8504416 D0 SE 8504416D0 SE 8504416 A SE8504416 A SE 8504416A SE 8504416 A SE8504416 A SE 8504416A SE 8504416 D0 SE8504416 D0 SE 8504416D0
- Authority
- SE
- Sweden
- Prior art keywords
- acid
- hydrosulfide
- thioglycolic acid
- monochloroacetic
- ratio
- Prior art date
Links
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 title abstract 8
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- JXTHNDFMNIQAHM-UHFFFAOYSA-N dichloroacetic acid Chemical compound OC(=O)C(Cl)Cl JXTHNDFMNIQAHM-UHFFFAOYSA-N 0.000 abstract 6
- FOCAUTSVDIKZOP-UHFFFAOYSA-N chloroacetic acid Chemical compound OC(=O)CCl FOCAUTSVDIKZOP-UHFFFAOYSA-N 0.000 abstract 3
- 229960005215 dichloroacetic acid Drugs 0.000 abstract 3
- RWSOTUBLDIXVET-UHFFFAOYSA-M hydrosulfide Chemical compound [SH-] RWSOTUBLDIXVET-UHFFFAOYSA-M 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- -1 alkaline earth metal hydrosulfide Chemical class 0.000 abstract 1
- 239000007791 liquid phase Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000004064 recycling Methods 0.000 abstract 1
- UVZICZIVKIMRNE-UHFFFAOYSA-N thiodiacetic acid Chemical compound OC(=O)CSCC(O)=O UVZICZIVKIMRNE-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Thioglycolic acid is made by contacting in a reaction zone at elevated pressure of H2S gas of at least 250 psig (1723 kPa) a mixture of monochloroacetic acid and dichloroacetic acid with a molar excess of an alkali metal or alkaline earth metal hydrosulfide to form the metal salt of thioglycolic acid, acidifying said salt and removing the free thioglycolic acid. The ratio of monochloroacetic acid to dichloroacetic acid is 99:1 to 75:25 by weight, the molar ratio of hydrosulfide to monochloroacetic acid is at least 2.1 and the under ratio of hydrosulfide to dichloroacetic acid is at least 3.1. A preferred process further requires separating any formed thiodiglycolic acid from the resultant liquid phase materials and recycling said acid to the reaction zone.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65558684A | 1984-09-28 | 1984-09-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8504416D0 true SE8504416D0 (en) | 1985-09-24 |
| SE8504416L SE8504416L (en) | 1986-03-29 |
Family
ID=24629498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8504416A SE8504416L (en) | 1984-09-28 | 1985-09-24 | SYNTHESIS OF THIOGLYCOLIC ACID |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS61118358A (en) |
| BE (1) | BE903323A (en) |
| DE (1) | DE3534612A1 (en) |
| FR (1) | FR2571051A1 (en) |
| GB (1) | GB2164939A (en) |
| IT (1) | IT1201473B (en) |
| LU (1) | LU86097A1 (en) |
| NL (1) | NL8502488A (en) |
| SE (1) | SE8504416L (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2135836T3 (en) * | 1995-12-21 | 1999-11-01 | Akzo Nobel Nv | PROCEDURE FOR THE PREPARATION OF THIOGLICOLICO ACID. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5129440A (en) * | 1974-09-05 | 1976-03-12 | Otsuka Kagaku Yakuhin | CHIOGURIKOORUSANNOSEIZOHO |
| DE2711867A1 (en) * | 1977-03-18 | 1978-09-21 | Hoechst Ag | Thioglycolic acid prepn. - by reacting mono-chloroacetic acid with e.g. Gp=IA or Gp=IIA metal bi:sulphide in aq. medium under carbon di:oxide pressure |
-
1985
- 1985-09-11 NL NL8502488A patent/NL8502488A/en not_active Application Discontinuation
- 1985-09-24 SE SE8504416A patent/SE8504416L/en not_active Application Discontinuation
- 1985-09-25 LU LU86097A patent/LU86097A1/en unknown
- 1985-09-25 JP JP60210346A patent/JPS61118358A/en active Granted
- 1985-09-26 IT IT22282/85A patent/IT1201473B/en active
- 1985-09-26 BE BE0/215640A patent/BE903323A/en not_active IP Right Cessation
- 1985-09-26 DE DE19853534612 patent/DE3534612A1/en not_active Withdrawn
- 1985-09-27 FR FR8514387A patent/FR2571051A1/en not_active Withdrawn
- 1985-09-27 GB GB08523818A patent/GB2164939A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| SE8504416L (en) | 1986-03-29 |
| IT1201473B (en) | 1989-02-02 |
| FR2571051A1 (en) | 1986-04-04 |
| DE3534612A1 (en) | 1986-04-17 |
| IT8522282A0 (en) | 1985-09-26 |
| LU86097A1 (en) | 1986-03-11 |
| NL8502488A (en) | 1986-04-16 |
| JPH0584307B2 (en) | 1993-12-01 |
| GB2164939A (en) | 1986-04-03 |
| GB8523818D0 (en) | 1985-10-30 |
| BE903323A (en) | 1986-01-16 |
| JPS61118358A (en) | 1986-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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