SE8305329L - Vektor och mikroorganism innehallande tillvexthormongener samt framstellning av nemnda vektor och mikroorganism - Google Patents
Vektor och mikroorganism innehallande tillvexthormongener samt framstellning av nemnda vektor och mikroorganismInfo
- Publication number
- SE8305329L SE8305329L SE8305329A SE8305329A SE8305329L SE 8305329 L SE8305329 L SE 8305329L SE 8305329 A SE8305329 A SE 8305329A SE 8305329 A SE8305329 A SE 8305329A SE 8305329 L SE8305329 L SE 8305329L
- Authority
- SE
- Sweden
- Prior art keywords
- dna
- growth hormone
- gene
- contg
- sub
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title claims abstract 4
- 102000018997 Growth Hormone Human genes 0.000 title claims abstract 3
- 108010051696 Growth Hormone Proteins 0.000 title claims abstract 3
- 239000000122 growth hormone Substances 0.000 title claims abstract 3
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 4
- 102000004877 Insulin Human genes 0.000 title abstract 2
- 108090001061 Insulin Proteins 0.000 title abstract 2
- 229940125396 insulin Drugs 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000013612 plasmid Substances 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 244000005700 microbiome Species 0.000 claims abstract 4
- 239000002773 nucleotide Substances 0.000 claims abstract 3
- 125000003729 nucleotide group Chemical group 0.000 claims abstract 3
- 230000001131 transforming effect Effects 0.000 claims 1
- 108020004635 Complementary DNA Proteins 0.000 abstract 3
- 238000010804 cDNA synthesis Methods 0.000 abstract 3
- 239000002299 complementary DNA Substances 0.000 abstract 3
- 108020004414 DNA Proteins 0.000 abstract 1
- 101000976075 Homo sapiens Insulin Proteins 0.000 abstract 1
- 102000002265 Human Growth Hormone Human genes 0.000 abstract 1
- 108010000521 Human Growth Hormone Proteins 0.000 abstract 1
- 239000000854 Human Growth Hormone Substances 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- PBGKTOXHQIOBKM-FHFVDXKLSA-N insulin (human) Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 PBGKTOXHQIOBKM-FHFVDXKLSA-N 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57518—Placental lactogen; Chorionic somatomammotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Crystallography & Structural Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Claims (1)
1. Patentkrav DNA-overforingsvektor for transformering av en mikroorganism, i vars nukleotidsekvens ingAr en delsekvens, coin bar strukturen av och ar transkriberad fran en naturlig gee av en Mare organism, vilken gen kodar for tillvaxthormon.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80134377A | 1977-05-27 | 1977-05-27 | |
US80502377A | 1977-06-09 | 1977-06-09 | |
US89770978A | 1978-04-19 | 1978-04-19 | |
US05897710 US4363877B1 (en) | 1977-09-23 | 1978-04-19 | Recombinant dna transfer vectors |
US05/898,887 US4264731A (en) | 1977-05-27 | 1978-04-21 | DNA Joining method |
US89900378A | 1978-04-26 | 1978-04-26 | |
US89900278A | 1978-04-26 | 1978-04-26 |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8305329D0 SE8305329D0 (sv) | 1983-09-29 |
SE8305329L true SE8305329L (sv) | 1983-09-29 |
SE455794B SE455794B (sv) | 1988-08-08 |
Family
ID=27569921
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7806086A SE451461B (sv) | 1977-05-27 | 1978-05-26 | Plasmid med nukleotidsekvens innehallande en sekvens som kodar for a- eller b-kedjan i insulin och forfarande for dess framstellning samt e.coli innehallande plasmiden och forfarande for framstellning av e.coli |
SE8305329A SE455794B (sv) | 1977-05-27 | 1983-09-29 | Plasmid med nukleotidsekvens som kodar for aminosyrasekvensen i humant tillvexthormon och forfarande for framstellning derav |
SE8305327A SE8305327L (sv) | 1977-05-27 | 1983-09-29 | Isolering av differentierade celler |
SE8305328A SE8305328L (sv) | 1977-05-27 | 1983-09-29 | Isolering av icke nedbruten rna |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7806086A SE451461B (sv) | 1977-05-27 | 1978-05-26 | Plasmid med nukleotidsekvens innehallande en sekvens som kodar for a- eller b-kedjan i insulin och forfarande for dess framstellning samt e.coli innehallande plasmiden och forfarande for framstellning av e.coli |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8305327A SE8305327L (sv) | 1977-05-27 | 1983-09-29 | Isolering av differentierade celler |
SE8305328A SE8305328L (sv) | 1977-05-27 | 1983-09-29 | Isolering av icke nedbruten rna |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPH0659218B2 (sv) |
AR (1) | AR225404A1 (sv) |
AU (1) | AU521903B2 (sv) |
BE (1) | BE867424A (sv) |
BG (1) | BG40319A3 (sv) |
CH (1) | CH642680A5 (sv) |
DD (1) | DD145927A5 (sv) |
DE (2) | DE2858357C2 (sv) |
DK (2) | DK233278A (sv) |
FI (1) | FI64640C (sv) |
FR (1) | FR2392033B1 (sv) |
GB (1) | GB1565190A (sv) |
GR (1) | GR73552B (sv) |
IL (1) | IL54790A (sv) |
IT (1) | IT1094934B (sv) |
LU (1) | LU79714A1 (sv) |
NL (1) | NL7805591A (sv) |
NZ (1) | NZ187300A (sv) |
PL (1) | PL140200B1 (sv) |
PT (1) | PT68082B (sv) |
SE (4) | SE451461B (sv) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA782933B (en) * | 1977-09-23 | 1979-05-30 | Univ California | Purification of nucleotide sequences suitable for expression in bacteria |
FR2422717B1 (fr) * | 1977-11-08 | 1985-12-06 | Genentech Inc | Procede permettant l'expression microbienne de polypeptides et moyens appropries |
GR71912B (sv) * | 1978-08-11 | 1983-08-16 | Univ California | |
US6297355B1 (en) | 1978-12-22 | 2001-10-02 | Biogen, Inc. | Polypeptides displaying HBV antigenicity or hbv antigen specificity |
JPS55150883A (en) * | 1979-05-11 | 1980-11-25 | Nakano Vinegar Co Ltd | Method of storing "mozuku" |
ZA802992B (en) * | 1979-06-01 | 1981-10-28 | Univ California | Human pre-growth hormone |
FR2458584A1 (fr) * | 1979-06-08 | 1981-01-02 | Pasteur Institut | Vecteurs pour le transfert et l'expression de materiel genetique dans une cellule eucaryote et procede pour la production d'une proteine determinee dans des cellules eucaryotes |
US4342832A (en) * | 1979-07-05 | 1982-08-03 | Genentech, Inc. | Method of constructing a replicable cloning vehicle having quasi-synthetic genes |
GR70279B (sv) * | 1979-09-12 | 1982-09-03 | Univ California | |
IL58765A (en) * | 1979-11-21 | 1986-09-30 | Yeda Res & Dev | Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta |
DE3001928A1 (de) * | 1980-01-19 | 1981-08-06 | Hoechst Ag, 6000 Frankfurt | Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus |
IL61982A (en) * | 1980-02-15 | 1984-01-31 | Cpc International Inc | Genetically engineered microorganisms for massive production of amyloytic enzymes and process for preparing same using the corresponding recombinant dnas containing amylase coding genes |
US4350764A (en) * | 1980-03-10 | 1982-09-21 | The Regents Of The University Of California | Microbiological synthesis of beta endorphin |
CA1202581A (en) * | 1980-03-27 | 1986-04-01 | Saran A. Narang | Adaptor molecules for dna and their application to synthesis of gene-derived products |
US4370417A (en) * | 1980-04-03 | 1983-01-25 | Abbott Laboratories | Recombinant deoxyribonucleic acid which codes for plasminogen activator |
US4338397A (en) | 1980-04-11 | 1982-07-06 | President And Fellows Of Harvard College | Mature protein synthesis |
BR8108074A (pt) * | 1980-12-12 | 1982-09-21 | Unilever Nv | Sequencia de dna,plasmidio recombinante,ligadores de dna,cultura bacterial e processo para produzir taumatina |
CA1193207A (en) * | 1980-12-12 | 1985-09-10 | Cornelis T. Verrips | Structural genes encoding the various allelic maturation forms of preprothaumatin, recombinant cloning vehicles, comprising said structural genes and expression thereof in transformed microbial host cells |
US4748233A (en) * | 1982-03-23 | 1988-05-31 | Bristol-Myers Company | Alpha-interferon Gx-1 |
US4695543A (en) * | 1982-03-23 | 1987-09-22 | Bristol-Myers Company | Alpha Interferon GX-1 |
CA1224432A (en) * | 1982-08-17 | 1987-07-21 | Gary N. Buell | Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield |
US5474980A (en) * | 1984-10-04 | 1995-12-12 | Monsanto Company | Prolonged release of biologically active somatotropins |
US5411951A (en) * | 1984-10-04 | 1995-05-02 | Monsanto Company | Prolonged release of biologically active somatotropin |
DK257988D0 (da) * | 1988-05-11 | 1988-05-11 | Novo Industri As | Nye peptider |
DE4034702A1 (de) * | 1990-10-31 | 1992-05-07 | Siemens Ag | Verfahren und vorrichtung zur pruefung der aktiven werkzeuge von gesenkbiegemaschinen, insbesondere von biegestempeln |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1521032A (en) * | 1974-08-08 | 1978-08-09 | Ici Ltd | Biological treatment |
-
1978
- 1978-05-17 NZ NZ187300A patent/NZ187300A/xx unknown
- 1978-05-23 NL NL7805591A patent/NL7805591A/ not_active Application Discontinuation
- 1978-05-23 GR GR56309A patent/GR73552B/el unknown
- 1978-05-23 AR AR272286A patent/AR225404A1/es active
- 1978-05-24 DE DE2858357A patent/DE2858357C2/de not_active Expired - Lifetime
- 1978-05-24 BE BE187995A patent/BE867424A/xx not_active IP Right Cessation
- 1978-05-24 PT PT68082A patent/PT68082B/pt unknown
- 1978-05-24 DE DE19782822568 patent/DE2822568A1/de active Granted
- 1978-05-25 FR FR7815596A patent/FR2392033B1/fr not_active Expired
- 1978-05-25 AU AU36488/78A patent/AU521903B2/en not_active Expired
- 1978-05-25 DD DD78205588A patent/DD145927A5/de unknown
- 1978-05-25 GB GB22417/78A patent/GB1565190A/en not_active Expired
- 1978-05-26 FI FI781675A patent/FI64640C/fi not_active IP Right Cessation
- 1978-05-26 LU LU79714A patent/LU79714A1/xx unknown
- 1978-05-26 CH CH581078A patent/CH642680A5/de not_active IP Right Cessation
- 1978-05-26 SE SE7806086A patent/SE451461B/sv unknown
- 1978-05-26 IL IL54790A patent/IL54790A/xx unknown
- 1978-05-26 DK DK782332A patent/DK233278A/da not_active Application Discontinuation
- 1978-05-27 PL PL1978207176A patent/PL140200B1/pl unknown
- 1978-05-27 JP JP53063756A patent/JPH0659218B2/ja not_active Expired - Lifetime
- 1978-05-27 BG BG039878A patent/BG40319A3/xx unknown
- 1978-05-29 IT IT23930/78A patent/IT1094934B/it active
-
1983
- 1983-09-29 SE SE8305329A patent/SE455794B/sv not_active Application Discontinuation
- 1983-09-29 SE SE8305327A patent/SE8305327L/sv not_active Application Discontinuation
- 1983-09-29 SE SE8305328A patent/SE8305328L/sv not_active Application Discontinuation
-
1991
- 1991-01-04 DK DK000791A patent/DK791A/da not_active Application Discontinuation
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