SE8304218D0 - prostaglandin derivative - Google Patents

prostaglandin derivative

Info

Publication number
SE8304218D0
SE8304218D0 SE8304218A SE8304218A SE8304218D0 SE 8304218 D0 SE8304218 D0 SE 8304218D0 SE 8304218 A SE8304218 A SE 8304218A SE 8304218 A SE8304218 A SE 8304218A SE 8304218 D0 SE8304218 D0 SE 8304218D0
Authority
SE
Sweden
Prior art keywords
prostaglandin derivative
lactones
hydroxy
didehydro
analogues
Prior art date
Application number
SE8304218A
Other languages
Swedish (sv)
Other versions
SE8304218L (en
Inventor
U F Axen
R A Johnson
R C Kelly
F H Lincoln
J E Pike
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/819,941 external-priority patent/US4124599A/en
Priority claimed from US05/819,856 external-priority patent/US4123441A/en
Priority claimed from US05/819,857 external-priority patent/US4158667A/en
Priority claimed from US05/819,940 external-priority patent/US4499293A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of SE8304218L publication Critical patent/SE8304218L/en
Publication of SE8304218D0 publication Critical patent/SE8304218D0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Pharmaceutically useful compounds are amido derivatives of known prostaglandins having a 6- oxo and a 9 alpha -hydroxy or hydroxymethyl group, and 6,9-lactones thereof, and a 6-hydroxy, 5-halo and 5,6-didehydro analogues of the lactones.
SE8304218A 1977-07-28 1983-08-01 prostaglandin derivative SE8304218D0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US05/819,941 US4124599A (en) 1976-09-22 1977-07-28 Enlarged-hetero-ring prostacyclin analogs
US05/819,856 US4123441A (en) 1976-09-22 1977-07-28 Enlarged-hetero-ring prostacyclin analogs
US05/819,857 US4158667A (en) 1976-02-04 1977-07-28 6-Keto PGF analogs
US05/819,940 US4499293A (en) 1976-09-22 1977-07-28 PGI2 Salts

Publications (2)

Publication Number Publication Date
SE8304218L SE8304218L (en) 1983-08-01
SE8304218D0 true SE8304218D0 (en) 1983-08-01

Family

ID=27505860

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7808040A SE7808040L (en) 1977-07-28 1978-07-21 PROSTAGLAND INDIVIDUALS
SE8304219A SE8304219D0 (en) 1977-07-28 1983-08-01 prostaglandin derivative
SE8304218A SE8304218D0 (en) 1977-07-28 1983-08-01 prostaglandin derivative

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE7808040A SE7808040L (en) 1977-07-28 1978-07-21 PROSTAGLAND INDIVIDUALS
SE8304219A SE8304219D0 (en) 1977-07-28 1983-08-01 prostaglandin derivative

Country Status (11)

Country Link
JP (1) JPS5427545A (en)
AU (1) AU527238B2 (en)
CH (1) CH639378A5 (en)
DE (1) DE2832372A1 (en)
FR (4) FR2408588A1 (en)
GB (1) GB2001636B (en)
IE (1) IE47284B1 (en)
IL (1) IL55097A0 (en)
IT (1) IT1098350B (en)
NL (1) NL7807543A (en)
SE (3) SE7808040L (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
IT1098350B (en) * 1977-07-28 1985-09-07 Upjohn Co PROSTAGLANDINIC DERIVATIVES
DE2811950A1 (en) * 1978-03-18 1979-12-13 Hoechst Ag NEW PROSTACYCLIN ANALOGS
US5185374A (en) * 1988-05-11 1993-02-09 K.K. Ueno Seiyaku Oyo Kenkyujo Use of 15-ketoprostaglandin E or F compounds for uterine contraction
MXPA04002006A (en) * 2001-08-31 2004-06-07 Sucampo Ag Prostaglandin analogs as chloride channel opener.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2351112A1 (en) * 1975-10-21 1977-12-09 Wellcome Found Prostaglandin derivs.
US4035642A (en) * 1976-08-20 1977-07-12 Rohm And Haas Company Gamma counter apparatus
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
IT1098350B (en) * 1977-07-28 1985-09-07 Upjohn Co PROSTAGLANDINIC DERIVATIVES
IT1088036B (en) * 1977-11-25 1985-06-04 Erba Carlo Spa 15-EPI-PROSTACYCLINE AND ANALOG PROSTACYCLINE

Also Published As

Publication number Publication date
IE47284B1 (en) 1984-02-08
FR2401921A1 (en) 1979-03-30
FR2408588A1 (en) 1979-06-08
AU3788278A (en) 1980-01-17
IE781522L (en) 1979-01-28
FR2401921B1 (en) 1982-10-22
GB2001636A (en) 1979-02-07
SE8304219L (en) 1983-08-01
IL55097A0 (en) 1978-09-29
FR2401920A1 (en) 1979-03-30
AU527238B2 (en) 1983-02-24
FR2401919B1 (en) 1982-10-22
NL7807543A (en) 1979-01-30
GB2001636B (en) 1982-03-17
IT1098350B (en) 1985-09-07
DE2832372A1 (en) 1979-02-08
JPS5427545A (en) 1979-03-01
SE8304218L (en) 1983-08-01
FR2401920B1 (en) 1982-11-19
SE8304219D0 (en) 1983-08-01
IT7825225A0 (en) 1978-06-30
FR2401919A1 (en) 1979-03-30
SE7808040L (en) 1979-01-29
CH639378A5 (en) 1983-11-15

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