SE8107446L - Nytt forfarande for framstellning av buspiron - Google Patents
Nytt forfarande for framstellning av buspironInfo
- Publication number
- SE8107446L SE8107446L SE8107446A SE8107446A SE8107446L SE 8107446 L SE8107446 L SE 8107446L SE 8107446 A SE8107446 A SE 8107446A SE 8107446 A SE8107446 A SE 8107446A SE 8107446 L SE8107446 L SE 8107446L
- Authority
- SE
- Sweden
- Prior art keywords
- buspiron
- preparation
- new procedure
- busipirone
- new
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- UNCQVRBWJWWJBF-UHFFFAOYSA-N 2-chloropyrimidine Chemical compound ClC1=NC=CC=N1 UNCQVRBWJWWJBF-UHFFFAOYSA-N 0.000 abstract 2
- 150000005695 2-halopyrimidines Chemical class 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 125000000246 pyrimidin-2-yl group Chemical group [H]C1=NC(*)=NC([H])=C1[H] 0.000 abstract 1
- 230000002285 radioactive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21521480A | 1980-12-11 | 1980-12-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8107446L true SE8107446L (sv) | 1982-06-12 |
SE444438B SE444438B (sv) | 1986-04-14 |
Family
ID=22802113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8107446A SE444438B (sv) | 1980-12-11 | 1981-12-11 | Forfarande for framstellning av radioaktivt merkt buspiron |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS57122082A (sv) |
AT (1) | AT380686B (sv) |
AU (1) | AU528067B2 (sv) |
BE (1) | BE891446A (sv) |
CA (1) | CA1172255A (sv) |
CH (1) | CH647518A5 (sv) |
DE (1) | DE3149011A1 (sv) |
DK (1) | DK154560C (sv) |
FI (1) | FI73993C (sv) |
FR (1) | FR2496105B1 (sv) |
GB (1) | GB2089341B (sv) |
GR (1) | GR76331B (sv) |
IE (1) | IE51948B1 (sv) |
IT (1) | IT1172073B (sv) |
LU (1) | LU83833A1 (sv) |
NL (1) | NL8105529A (sv) |
SE (1) | SE444438B (sv) |
YU (1) | YU42432B (sv) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU212301B (en) * | 1989-04-28 | 1996-05-28 | Alkaloida Vegyeszeti Gyar | Process for producing buspirone |
US5484788A (en) * | 1993-03-26 | 1996-01-16 | Beth Israel Hospital Association | Buspirone as a systemic immunosuppressant |
US5631017A (en) * | 1993-03-26 | 1997-05-20 | Beth Israel Deaconess Medical Center, Inc. | Topical application of buspirone for treatment of pathological conditions associated with immune responses |
KR950014099A (ko) * | 1993-11-10 | 1995-06-15 | 장기하 | N-(2-피리미딜)피페라지닐 부틸아미드의 제조방법 |
US5637314A (en) * | 1995-06-07 | 1997-06-10 | Beth Israel Deaconess Medical Center, Inc. | Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE759371A (fr) * | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
DE2341925A1 (de) * | 1973-08-20 | 1975-03-06 | Thomae Gmbh Dr K | Neue pyrimidinderivate und verfahren zu ihrer herstellung |
-
1981
- 1981-09-29 CA CA000386889A patent/CA1172255A/en not_active Expired
- 1981-10-05 AU AU76041/81A patent/AU528067B2/en not_active Expired
- 1981-10-09 YU YU2436/81A patent/YU42432B/xx unknown
- 1981-10-27 GB GB8132370A patent/GB2089341B/en not_active Expired
- 1981-11-16 IT IT49718/81A patent/IT1172073B/it active
- 1981-11-27 GR GR66636A patent/GR76331B/el unknown
- 1981-12-08 NL NL8105529A patent/NL8105529A/nl active Search and Examination
- 1981-12-08 FI FI813937A patent/FI73993C/sv not_active IP Right Cessation
- 1981-12-08 FR FR8122916A patent/FR2496105B1/fr not_active Expired
- 1981-12-08 CH CH7842/81A patent/CH647518A5/de not_active IP Right Cessation
- 1981-12-09 JP JP56197037A patent/JPS57122082A/ja active Granted
- 1981-12-10 DK DK548081A patent/DK154560C/da not_active IP Right Cessation
- 1981-12-10 DE DE19813149011 patent/DE3149011A1/de active Granted
- 1981-12-10 AT AT0529581A patent/AT380686B/de not_active IP Right Cessation
- 1981-12-10 IE IE2897/81A patent/IE51948B1/en not_active IP Right Cessation
- 1981-12-11 SE SE8107446A patent/SE444438B/sv not_active IP Right Cessation
- 1981-12-11 LU LU83833A patent/LU83833A1/fr unknown
- 1981-12-11 BE BE0/206810A patent/BE891446A/fr not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE444438B (sv) | 1986-04-14 |
IE812897L (en) | 1982-06-11 |
LU83833A1 (fr) | 1982-07-07 |
DK548081A (da) | 1982-06-12 |
GR76331B (sv) | 1984-08-04 |
FI73993C (sv) | 1987-12-10 |
CA1172255A (en) | 1984-08-07 |
BE891446A (fr) | 1982-06-11 |
FI813937L (fi) | 1982-06-12 |
FR2496105A1 (fr) | 1982-06-18 |
AU7604181A (en) | 1982-07-15 |
IT8149718A0 (it) | 1981-11-16 |
DK154560C (da) | 1989-04-17 |
NL8105529A (nl) | 1982-07-01 |
AU528067B2 (en) | 1983-04-14 |
FR2496105B1 (fr) | 1985-12-13 |
GB2089341A (en) | 1982-06-23 |
ATA529581A (de) | 1985-11-15 |
GB2089341B (en) | 1984-09-19 |
DE3149011C2 (sv) | 1988-08-25 |
JPH0113476B2 (sv) | 1989-03-06 |
IT1172073B (it) | 1987-06-18 |
IE51948B1 (en) | 1987-04-29 |
AT380686B (de) | 1986-06-25 |
YU243681A (en) | 1984-02-29 |
CH647518A5 (de) | 1985-01-31 |
DK154560B (da) | 1988-11-28 |
DE3149011A1 (de) | 1982-07-15 |
JPS57122082A (en) | 1982-07-29 |
YU42432B (en) | 1988-08-31 |
FI73993B (fi) | 1987-08-31 |
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