JPS57122082A - Buspirone manufacture - Google Patents

Buspirone manufacture

Info

Publication number
JPS57122082A
JPS57122082A JP56197037A JP19703781A JPS57122082A JP S57122082 A JPS57122082 A JP S57122082A JP 56197037 A JP56197037 A JP 56197037A JP 19703781 A JP19703781 A JP 19703781A JP S57122082 A JPS57122082 A JP S57122082A
Authority
JP
Japan
Prior art keywords
buspirone
manufacture
buspirone manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56197037A
Other languages
Japanese (ja)
Other versions
JPH0113476B2 (en
Inventor
Aaru Kobinton Robaato
Eru Tenpuru Jiyunia Deibisu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of JPS57122082A publication Critical patent/JPS57122082A/en
Publication of JPH0113476B2 publication Critical patent/JPH0113476B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20Spiro-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/34One oxygen atom
    • C07D239/36One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP56197037A 1980-12-11 1981-12-09 Buspirone manufacture Granted JPS57122082A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21521480A 1980-12-11 1980-12-11

Publications (2)

Publication Number Publication Date
JPS57122082A true JPS57122082A (en) 1982-07-29
JPH0113476B2 JPH0113476B2 (en) 1989-03-06

Family

ID=22802113

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56197037A Granted JPS57122082A (en) 1980-12-11 1981-12-09 Buspirone manufacture

Country Status (18)

Country Link
JP (1) JPS57122082A (en)
AT (1) AT380686B (en)
AU (1) AU528067B2 (en)
BE (1) BE891446A (en)
CA (1) CA1172255A (en)
CH (1) CH647518A5 (en)
DE (1) DE3149011A1 (en)
DK (1) DK154560C (en)
FI (1) FI73993C (en)
FR (1) FR2496105B1 (en)
GB (1) GB2089341B (en)
GR (1) GR76331B (en)
IE (1) IE51948B1 (en)
IT (1) IT1172073B (en)
LU (1) LU83833A1 (en)
NL (1) NL8105529A (en)
SE (1) SE444438B (en)
YU (1) YU42432B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU212301B (en) * 1989-04-28 1996-05-28 Alkaloida Vegyeszeti Gyar Process for producing buspirone
US5484788A (en) * 1993-03-26 1996-01-16 Beth Israel Hospital Association Buspirone as a systemic immunosuppressant
US5631017A (en) * 1993-03-26 1997-05-20 Beth Israel Deaconess Medical Center, Inc. Topical application of buspirone for treatment of pathological conditions associated with immune responses
KR950014099A (en) * 1993-11-10 1995-06-15 장기하 Method for preparing N- (2-pyrimidyl) piperazinyl butylamide
US5637314A (en) * 1995-06-07 1997-06-10 Beth Israel Deaconess Medical Center, Inc. Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5049288A (en) * 1973-08-20 1975-05-01 Thomae Gmbh Dr K Shinkina pirimijinkagobutsuno seizohoho

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (en) * 1969-11-24 1971-05-24 Bristol Myers Co HETEROCYCLICAL AZASPIRODECANEDIONES AND METHODS FOR THEIR PREPARATION

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5049288A (en) * 1973-08-20 1975-05-01 Thomae Gmbh Dr K Shinkina pirimijinkagobutsuno seizohoho

Also Published As

Publication number Publication date
DK154560C (en) 1989-04-17
ATA529581A (en) 1985-11-15
DE3149011A1 (en) 1982-07-15
JPH0113476B2 (en) 1989-03-06
YU42432B (en) 1988-08-31
FI73993C (en) 1987-12-10
YU243681A (en) 1984-02-29
CA1172255A (en) 1984-08-07
AU528067B2 (en) 1983-04-14
SE444438B (en) 1986-04-14
IE51948B1 (en) 1987-04-29
IE812897L (en) 1982-06-11
IT8149718A0 (en) 1981-11-16
DE3149011C2 (en) 1988-08-25
FR2496105A1 (en) 1982-06-18
FI813937L (en) 1982-06-12
DK154560B (en) 1988-11-28
AU7604181A (en) 1982-07-15
FR2496105B1 (en) 1985-12-13
CH647518A5 (en) 1985-01-31
NL8105529A (en) 1982-07-01
FI73993B (en) 1987-08-31
IT1172073B (en) 1987-06-18
DK548081A (en) 1982-06-12
GB2089341A (en) 1982-06-23
LU83833A1 (en) 1982-07-07
GR76331B (en) 1984-08-04
BE891446A (en) 1982-06-11
GB2089341B (en) 1984-09-19
SE8107446L (en) 1982-06-12
AT380686B (en) 1986-06-25

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