SE7903672L - NEW ANTIBIOTIC NEPLANOCIN - Google Patents

NEW ANTIBIOTIC NEPLANOCIN

Info

Publication number
SE7903672L
SE7903672L SE7903672A SE7903672A SE7903672L SE 7903672 L SE7903672 L SE 7903672L SE 7903672 A SE7903672 A SE 7903672A SE 7903672 A SE7903672 A SE 7903672A SE 7903672 L SE7903672 L SE 7903672L
Authority
SE
Sweden
Prior art keywords
group
neplanocin
new antibiotic
image
hydrogen atom
Prior art date
Application number
SE7903672A
Other languages
Swedish (sv)
Other versions
SE443576B (en
Inventor
M Otani
S Yaginuma
M Tsujino
N Muto
T Saito
T Fujii
Original Assignee
Tokyo Jozo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP6289978A external-priority patent/JPS54154792A/en
Priority claimed from JP9802778A external-priority patent/JPS5524157A/en
Priority claimed from JP820579A external-priority patent/JPS55100388A/en
Priority claimed from JP2120179A external-priority patent/JPS55113786A/en
Application filed by Tokyo Jozo Kk filed Critical Tokyo Jozo Kk
Publication of SE7903672L publication Critical patent/SE7903672L/en
Publication of SE443576B publication Critical patent/SE443576B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

The present invention provides antibiotic neplanocins of the general formula:- <IMAGE> wherein X is an NH2, -OH, -SH or -SCH3 group or a chlorine atom, R is a hydrogen atom or a protective group for the -OH group, and Z is a <IMAGE> group, in which Y is -O- or a valency bond and R is a hydrogen atom or a protective group for the -OH group, or Z is a group in which Y is -O- or a valency bond, and the physiologically- acceptable salts thereof. The present invention also provides processes for the production of these antibiotics and pharmaceutical compositions containing them.
SE7903672A 1978-05-25 1979-04-26 ANTIBIOTIC NEPLANOCINES AND PROCEDURE FOR PREPARING THEM THROUGH CULTIVATION OF AMPULLARIAL SP A 11079 NRRL 11451 SE443576B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP6289978A JPS54154792A (en) 1978-05-25 1978-05-25 Novel antibiotic a-11079-b1b and its preparation
JP9802778A JPS5524157A (en) 1978-08-10 1978-08-10 Novel antibiotic substance a-11079-b2 and its preparation
JP820579A JPS55100388A (en) 1979-01-29 1979-01-29 Novel substance neplanocin d and its derivative
JP2120179A JPS55113786A (en) 1979-02-23 1979-02-23 Novel substance, nepranosin b or f and its preparation

Publications (2)

Publication Number Publication Date
SE7903672L true SE7903672L (en) 1979-11-26
SE443576B SE443576B (en) 1986-03-03

Family

ID=27454901

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7903672A SE443576B (en) 1978-05-25 1979-04-26 ANTIBIOTIC NEPLANOCINES AND PROCEDURE FOR PREPARING THEM THROUGH CULTIVATION OF AMPULLARIAL SP A 11079 NRRL 11451

Country Status (13)

Country Link
CA (1) CA1128882A (en)
CH (1) CH641804A5 (en)
DE (2) DE2917000C2 (en)
DK (1) DK149313C (en)
ES (1) ES480384A1 (en)
FR (1) FR2426688A1 (en)
GB (1) GB2021582B (en)
HU (1) HU192741B (en)
IT (1) IT1115245B (en)
MX (1) MX5788E (en)
NL (1) NL182231C (en)
SE (1) SE443576B (en)
SU (1) SU906388A3 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3148363A1 (en) * 1980-12-12 1982-09-16 Toyo Jozo K.K., Shizuoka NEPLANOCIN A DERIVATIVES
US4742064A (en) * 1985-09-10 1988-05-03 Regents Of The University Of Minnesota Antiviral carbocyclic analogs of xylofuranosylpurines
ZA894534B (en) * 1988-06-20 1990-03-28 Merrell Dow Pharma Novel neplanocin derivatives
US5164520A (en) * 1989-04-24 1992-11-17 E. R. Squibb & Sons, Inc. Intermediates for purinyl and pyrimidinyl tetrahydrofurans
NZ232993A (en) * 1989-04-24 1992-10-28 Squibb & Sons Inc Purinyl and pyrimidinyl tetrahydrofurans
US5059690A (en) * 1990-03-01 1991-10-22 E. R. Squibb & Sons, Inc. Purinyl tetrahydrofurans
US5145960A (en) * 1989-04-24 1992-09-08 E. R. Squibb & Sons, Inc. Pyrimidinyl tetrahydrofurans

Also Published As

Publication number Publication date
DE2954197C2 (en) 1990-09-27
FR2426688A1 (en) 1979-12-21
ES480384A1 (en) 1980-04-01
FR2426688B1 (en) 1982-03-12
GB2021582A (en) 1979-12-05
DE2917000C2 (en) 1985-10-03
DK177079A (en) 1979-11-26
MX5788E (en) 1984-07-11
HU192741B (en) 1987-07-28
GB2021582B (en) 1982-10-20
IT1115245B (en) 1986-02-03
CH641804A5 (en) 1984-03-15
DE2917000A1 (en) 1979-11-29
NL7903318A (en) 1979-11-27
SE443576B (en) 1986-03-03
DK149313C (en) 1986-10-20
NL182231B (en) 1987-09-01
SU906388A3 (en) 1982-02-15
IT7922957A0 (en) 1979-05-24
CA1128882A (en) 1982-08-03
DK149313B (en) 1986-04-28
NL182231C (en) 1988-02-01

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