JPS5524157A - Novel antibiotic substance a-11079-b2 and its preparation - Google Patents
Novel antibiotic substance a-11079-b2 and its preparationInfo
- Publication number
- JPS5524157A JPS5524157A JP9802778A JP9802778A JPS5524157A JP S5524157 A JPS5524157 A JP S5524157A JP 9802778 A JP9802778 A JP 9802778A JP 9802778 A JP9802778 A JP 9802778A JP S5524157 A JPS5524157 A JP S5524157A
- Authority
- JP
- Japan
- Prior art keywords
- substance
- methanol
- water
- soluble
- antibiotic substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Antibiotic substance A-11079-B2 and its salt: Molecular weight, 279; molecular formula, C11H13N5O4; melting point, 226°C (decomposition); specific rotation, [d]D21-43.6° (C=0.67% H2O); solubility, soluble in water, dimethyl- sulfoxide, etc., slightly soluble in methanol, insoluble in ethyl acetate, chloroform, etc.; color reactions, KMnO4, positive; FeCl3, negative; weak basic; white.
USE: Antifungal agent which inhibits the growth of plant pathogenic mold.
PROCESS: The A-11079-B2 substance is prepared by (1) culturing Ampullariella sp. A11079 (FERM-P No.4494) in a liquid medium at 25W30°C under neutralW acidic conditions, (2) adsorbing the objective substance from the filtrate of the medium with activated charcoal, cation exchange resin, etc., (3) eluting the adsorbed substance with aqueous ammonia - water - methanol, and (4) purifying the eluate.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9802778A JPS5524157A (en) | 1978-08-10 | 1978-08-10 | Novel antibiotic substance a-11079-b2 and its preparation |
HU79TO1102A HU192741B (en) | 1978-05-25 | 1979-04-12 | Process for producing new neplanocin antibiotics |
SE7903672A SE443576B (en) | 1978-05-25 | 1979-04-26 | ANTIBIOTIC NEPLANOCINES AND PROCEDURE FOR PREPARING THEM THROUGH CULTIVATION OF AMPULLARIAL SP A 11079 NRRL 11451 |
NLAANVRAGE7903318,A NL182231C (en) | 1978-05-25 | 1979-04-26 | NEPLANOCIN ANTIBIOTICS AND A METHOD FOR THE PREPARATION THEREOF. |
DE2917000A DE2917000C2 (en) | 1978-05-25 | 1979-04-26 | 1β- (6-Amino-9H-purin-9-yl) -4-hydroxymethyl-4-cyclopentene-2α, 3α-diol (neplanocin A), process for its preparation and pharmaceutical compositions containing this compound |
DE2954197A DE2954197C2 (en) | 1978-05-25 | 1979-04-26 | |
DK177079A DK149313C (en) | 1978-05-25 | 1979-04-30 | METHOD FOR PREPARING A, B, C, D AND F NEPLANOCIN |
FR7911578A FR2426688A1 (en) | 1978-05-25 | 1979-05-08 | NEW ANTIBIOTIC NEPLANOCINS |
ES480384A ES480384A1 (en) | 1978-05-25 | 1979-05-09 | New antibiotics |
SU792763801A SU906388A3 (en) | 1978-05-25 | 1979-05-17 | Method for preparing antibiotic complex including neplanocins a,b,c,d and f |
GB7917481A GB2021582B (en) | 1978-05-25 | 1979-05-18 | Antibiotics |
CA328,113A CA1128882A (en) | 1978-05-25 | 1979-05-23 | Antibiotic neplanocins |
MX797996U MX5788E (en) | 1978-05-25 | 1979-05-23 | MICROBIOLOGICAL PROCEDURE FOR THE PREPARATION OF NEPLANOCINES |
IT7922957A IT1115245B (en) | 1978-05-25 | 1979-05-24 | ANTIBIOTICS OF THE NEPLANOCINE TYPE |
CH490879A CH641804A5 (en) | 1978-05-25 | 1979-05-25 | ANTIBIOTIC NEPLANOCINE. |
US06/205,350 US4423218A (en) | 1978-05-25 | 1980-11-03 | Antibiotic neplanocin A |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9802778A JPS5524157A (en) | 1978-08-10 | 1978-08-10 | Novel antibiotic substance a-11079-b2 and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5524157A true JPS5524157A (en) | 1980-02-21 |
JPS6212228B2 JPS6212228B2 (en) | 1987-03-17 |
Family
ID=14208454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9802778A Granted JPS5524157A (en) | 1978-05-25 | 1978-08-10 | Novel antibiotic substance a-11079-b2 and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5524157A (en) |
-
1978
- 1978-08-10 JP JP9802778A patent/JPS5524157A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6212228B2 (en) | 1987-03-17 |
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