JPS5524157A - Novel antibiotic substance a-11079-b2 and its preparation - Google Patents

Novel antibiotic substance a-11079-b2 and its preparation

Info

Publication number
JPS5524157A
JPS5524157A JP9802778A JP9802778A JPS5524157A JP S5524157 A JPS5524157 A JP S5524157A JP 9802778 A JP9802778 A JP 9802778A JP 9802778 A JP9802778 A JP 9802778A JP S5524157 A JPS5524157 A JP S5524157A
Authority
JP
Japan
Prior art keywords
substance
methanol
water
soluble
antibiotic substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9802778A
Other languages
Japanese (ja)
Other versions
JPS6212228B2 (en
Inventor
Tadayo Fujii
Satoshi Yaginuma
Masatoshi Tsujino
Naoki Muto
Masaru Kotani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Priority to JP9802778A priority Critical patent/JPS5524157A/en
Priority to HU79TO1102A priority patent/HU192741B/en
Priority to SE7903672A priority patent/SE443576B/en
Priority to NLAANVRAGE7903318,A priority patent/NL182231C/en
Priority to DE2917000A priority patent/DE2917000C2/en
Priority to DE2954197A priority patent/DE2954197C2/de
Priority to DK177079A priority patent/DK149313C/en
Priority to FR7911578A priority patent/FR2426688A1/en
Priority to ES480384A priority patent/ES480384A1/en
Priority to SU792763801A priority patent/SU906388A3/en
Priority to GB7917481A priority patent/GB2021582B/en
Priority to CA328,113A priority patent/CA1128882A/en
Priority to MX797996U priority patent/MX5788E/en
Priority to IT7922957A priority patent/IT1115245B/en
Priority to CH490879A priority patent/CH641804A5/en
Publication of JPS5524157A publication Critical patent/JPS5524157A/en
Priority to US06/205,350 priority patent/US4423218A/en
Publication of JPS6212228B2 publication Critical patent/JPS6212228B2/ja
Granted legal-status Critical Current

Links

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Antibiotic substance A-11079-B2 and its salt: Molecular weight, 279; molecular formula, C11H13N5O4; melting point, 226°C (decomposition); specific rotation, [d]D21-43.6° (C=0.67% H2O); solubility, soluble in water, dimethyl- sulfoxide, etc., slightly soluble in methanol, insoluble in ethyl acetate, chloroform, etc.; color reactions, KMnO4, positive; FeCl3, negative; weak basic; white.
USE: Antifungal agent which inhibits the growth of plant pathogenic mold.
PROCESS: The A-11079-B2 substance is prepared by (1) culturing Ampullariella sp. A11079 (FERM-P No.4494) in a liquid medium at 25W30°C under neutralW acidic conditions, (2) adsorbing the objective substance from the filtrate of the medium with activated charcoal, cation exchange resin, etc., (3) eluting the adsorbed substance with aqueous ammonia - water - methanol, and (4) purifying the eluate.
COPYRIGHT: (C)1980,JPO&Japio
JP9802778A 1978-05-25 1978-08-10 Novel antibiotic substance a-11079-b2 and its preparation Granted JPS5524157A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
JP9802778A JPS5524157A (en) 1978-08-10 1978-08-10 Novel antibiotic substance a-11079-b2 and its preparation
HU79TO1102A HU192741B (en) 1978-05-25 1979-04-12 Process for producing new neplanocin antibiotics
SE7903672A SE443576B (en) 1978-05-25 1979-04-26 ANTIBIOTIC NEPLANOCINES AND PROCEDURE FOR PREPARING THEM THROUGH CULTIVATION OF AMPULLARIAL SP A 11079 NRRL 11451
NLAANVRAGE7903318,A NL182231C (en) 1978-05-25 1979-04-26 NEPLANOCIN ANTIBIOTICS AND A METHOD FOR THE PREPARATION THEREOF.
DE2917000A DE2917000C2 (en) 1978-05-25 1979-04-26 1β- (6-Amino-9H-purin-9-yl) -4-hydroxymethyl-4-cyclopentene-2α, 3α-diol (neplanocin A), process for its preparation and pharmaceutical compositions containing this compound
DE2954197A DE2954197C2 (en) 1978-05-25 1979-04-26
DK177079A DK149313C (en) 1978-05-25 1979-04-30 METHOD FOR PREPARING A, B, C, D AND F NEPLANOCIN
FR7911578A FR2426688A1 (en) 1978-05-25 1979-05-08 NEW ANTIBIOTIC NEPLANOCINS
ES480384A ES480384A1 (en) 1978-05-25 1979-05-09 New antibiotics
SU792763801A SU906388A3 (en) 1978-05-25 1979-05-17 Method for preparing antibiotic complex including neplanocins a,b,c,d and f
GB7917481A GB2021582B (en) 1978-05-25 1979-05-18 Antibiotics
CA328,113A CA1128882A (en) 1978-05-25 1979-05-23 Antibiotic neplanocins
MX797996U MX5788E (en) 1978-05-25 1979-05-23 MICROBIOLOGICAL PROCEDURE FOR THE PREPARATION OF NEPLANOCINES
IT7922957A IT1115245B (en) 1978-05-25 1979-05-24 ANTIBIOTICS OF THE NEPLANOCINE TYPE
CH490879A CH641804A5 (en) 1978-05-25 1979-05-25 ANTIBIOTIC NEPLANOCINE.
US06/205,350 US4423218A (en) 1978-05-25 1980-11-03 Antibiotic neplanocin A

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9802778A JPS5524157A (en) 1978-08-10 1978-08-10 Novel antibiotic substance a-11079-b2 and its preparation

Publications (2)

Publication Number Publication Date
JPS5524157A true JPS5524157A (en) 1980-02-21
JPS6212228B2 JPS6212228B2 (en) 1987-03-17

Family

ID=14208454

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9802778A Granted JPS5524157A (en) 1978-05-25 1978-08-10 Novel antibiotic substance a-11079-b2 and its preparation

Country Status (1)

Country Link
JP (1) JPS5524157A (en)

Also Published As

Publication number Publication date
JPS6212228B2 (en) 1987-03-17

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