SE7714959L - NEW POLYMORPHICAL FORMS - Google Patents

NEW POLYMORPHICAL FORMS

Info

Publication number
SE7714959L
SE7714959L SE7714959A SE7714959A SE7714959L SE 7714959 L SE7714959 L SE 7714959L SE 7714959 A SE7714959 A SE 7714959A SE 7714959 A SE7714959 A SE 7714959A SE 7714959 L SE7714959 L SE 7714959L
Authority
SE
Sweden
Prior art keywords
modification
polymorphical
new
forms
rapidly
Prior art date
Application number
SE7714959A
Other languages
Swedish (sv)
Inventor
J G Baldinus
J E Zarembo
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of SE7714959L publication Critical patent/SE7714959L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

4-(2-Thenoyl)-2,3-dichlorophenoxyacetic acid of the polymorphic modification B, characterised by an infrared spectrum having strong absorption bands at 1725 and 1418 cm<-1> and a very weak absorption band at 1180 cm<-1>, and a melting point, determined by differential thermoanalysis, of 152 DEG C. This modification B can be prepared by recrystallising the modification A either a) slowly or rapidly from non-polar solvents, or b) rapidly from hot chloroform or ethylene dichloride.
SE7714959A 1977-01-07 1977-12-30 NEW POLYMORPHICAL FORMS SE7714959L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB56277 1977-01-07

Publications (1)

Publication Number Publication Date
SE7714959L true SE7714959L (en) 1978-07-08

Family

ID=9706556

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7714959A SE7714959L (en) 1977-01-07 1977-12-30 NEW POLYMORPHICAL FORMS

Country Status (18)

Country Link
JP (1) JPS5387349A (en)
AU (1) AU510569B2 (en)
BE (1) BE862688A (en)
CH (1) CH634066A5 (en)
DD (1) DD134096A5 (en)
DE (1) DE2800489A1 (en)
DK (1) DK565677A (en)
ES (1) ES465181A1 (en)
FR (1) FR2376856A1 (en)
GR (1) GR66062B (en)
IL (1) IL53651A0 (en)
IT (1) IT1089800B (en)
LU (1) LU78823A1 (en)
NL (1) NL7800213A (en)
PL (1) PL203865A1 (en)
PT (1) PT67416B (en)
SE (1) SE7714959L (en)
ZA (1) ZA777531B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996020939A1 (en) * 1995-01-04 1996-07-11 Ferrer Internacional, S.A. POLYMORPHS B AND C OF 1-[2,4-DICHLORO-β-[(7-CHLOROBENZO[b]THIEN-3-YL)METHOXY]PHENETYL]IMIDAZOLE MONONITRATE
WO2007064595A2 (en) * 2005-11-29 2007-06-07 Bausch & Lomb Incorporated Fluocinolone acetonide drug substance polymorphic interconversion

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2115042A2 (en) * 1970-11-25 1972-07-07 Cerpha 4-2-thienylketo-2,3-dichlorophenoxy acetic acid - prepn and purificn

Also Published As

Publication number Publication date
PT67416B (en) 1979-05-22
IL53651A0 (en) 1978-03-10
ZA777531B (en) 1978-10-25
PL203865A1 (en) 1979-06-04
FR2376856A1 (en) 1978-08-04
NL7800213A (en) 1978-07-11
AU3169877A (en) 1979-06-28
DK565677A (en) 1978-07-08
IT1089800B (en) 1985-06-18
ES465181A1 (en) 1979-01-01
JPS5387349A (en) 1978-08-01
PT67416A (en) 1978-01-01
LU78823A1 (en) 1978-06-09
GR66062B (en) 1981-01-15
FR2376856B1 (en) 1981-01-23
DE2800489A1 (en) 1978-07-13
CH634066A5 (en) 1983-01-14
BE862688A (en) 1978-07-06
DD134096A5 (en) 1979-02-07
AU510569B2 (en) 1980-07-03

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