SE7700490L - HYPOLIPIDEMIC P-AMINOBENZOIC ACIDS - Google Patents
HYPOLIPIDEMIC P-AMINOBENZOIC ACIDSInfo
- Publication number
- SE7700490L SE7700490L SE7700490A SE7700490A SE7700490L SE 7700490 L SE7700490 L SE 7700490L SE 7700490 A SE7700490 A SE 7700490A SE 7700490 A SE7700490 A SE 7700490A SE 7700490 L SE7700490 L SE 7700490L
- Authority
- SE
- Sweden
- Prior art keywords
- ylmethylamino
- benzodioxol
- formula
- hypolipidemic
- aminobenzoic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Schiff's bases of the formula I <IMAGE> in which R is hydrogen or lower alkyl are obtained by reacting piperonal with p-aminobenzoic acid or with a p-aminobenzoic ester. 4-(1,3-Benzodioxol-5-ylmethylamino)benzoic acid and 4-(1,3-benzodioxol-5-ylmethylamino)benzoic esters of the formula II <IMAGE> in which R is hydrogen or lower alkyl are obtained by reducing Schiff's bases of the formula I. The compound 4-(1,3-benzodioxol-5-ylmethylamino)benzoic acid which can be prepared according to the invention can be used, for example, for the reduction of the lipid level in the plasma of animals.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65009076A | 1976-01-19 | 1976-01-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7700490L true SE7700490L (en) | 1977-07-20 |
SE435175B SE435175B (en) | 1984-09-10 |
Family
ID=24607411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7700490A SE435175B (en) | 1976-01-19 | 1977-01-18 | METHOD OF PREPARING HYPOLIPIDEMIC 4-METHYLAMINOBENOIC ACIDS |
Country Status (14)
Country | Link |
---|---|
JP (1) | JPS5289660A (en) |
AT (1) | AT347923B (en) |
AU (1) | AU500881B2 (en) |
BE (1) | BE850516A (en) |
CA (1) | CA1072969A (en) |
CH (1) | CH628340A5 (en) |
DE (1) | DE2702058C2 (en) |
DK (1) | DK153471C (en) |
FR (1) | FR2338040A1 (en) |
GB (2) | GB1521459A (en) |
IE (1) | IE44858B1 (en) |
NL (1) | NL7700480A (en) |
NO (1) | NO145839C (en) |
SE (1) | SE435175B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0424904Y2 (en) * | 1987-09-18 | 1992-06-12 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE716668C (en) * | 1938-02-15 | 1942-01-27 | Dr Aladar Skita | Process for the preparation of derivatives of substituted aminobenzoic acids |
FR2080069A5 (en) * | 1970-02-23 | 1971-11-12 | Commissariat Energie Atomique | |
US3868416A (en) * | 1973-10-01 | 1975-02-25 | American Cyanamid Co | Hypolipidemic 4-(monoalkylamino)benzoic acid derivatives |
-
1977
- 1977-01-07 AU AU21140/77A patent/AU500881B2/en not_active Expired
- 1977-01-10 DK DK008177A patent/DK153471C/en not_active IP Right Cessation
- 1977-01-11 CA CA269,483A patent/CA1072969A/en not_active Expired
- 1977-01-17 GB GB52242/77A patent/GB1521459A/en not_active Expired
- 1977-01-17 JP JP384477A patent/JPS5289660A/en active Granted
- 1977-01-17 GB GB1803/77A patent/GB1521458A/en not_active Expired
- 1977-01-18 SE SE7700490A patent/SE435175B/en not_active IP Right Cessation
- 1977-01-18 FR FR7701296A patent/FR2338040A1/en active Granted
- 1977-01-18 NL NL7700480A patent/NL7700480A/en active Search and Examination
- 1977-01-18 NO NO770151A patent/NO145839C/en unknown
- 1977-01-19 BE BE174188A patent/BE850516A/en not_active IP Right Cessation
- 1977-01-19 CH CH65877A patent/CH628340A5/en not_active IP Right Cessation
- 1977-01-19 DE DE2702058A patent/DE2702058C2/en not_active Expired
- 1977-01-19 IE IE104/77A patent/IE44858B1/en not_active IP Right Cessation
- 1977-01-19 AT AT31277A patent/AT347923B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE2702058A1 (en) | 1977-07-28 |
AU500881B2 (en) | 1979-06-07 |
CA1072969A (en) | 1980-03-04 |
IE44858L (en) | 1977-07-19 |
AU2114077A (en) | 1978-07-13 |
JPS6233230B2 (en) | 1987-07-20 |
GB1521459A (en) | 1978-08-16 |
BE850516A (en) | 1977-07-19 |
DK153471C (en) | 1988-11-21 |
GB1521458A (en) | 1978-08-16 |
CH628340A5 (en) | 1982-02-26 |
DE2702058C2 (en) | 1985-09-19 |
NO145839B (en) | 1982-03-01 |
DK153471B (en) | 1988-07-18 |
DK8177A (en) | 1977-07-20 |
ATA31277A (en) | 1978-06-15 |
IE44858B1 (en) | 1982-04-21 |
FR2338040B1 (en) | 1980-04-30 |
NO145839C (en) | 1982-06-09 |
AT347923B (en) | 1979-01-25 |
FR2338040A1 (en) | 1977-08-12 |
NL7700480A (en) | 1977-07-21 |
NO770151L (en) | 1977-07-20 |
SE435175B (en) | 1984-09-10 |
JPS5289660A (en) | 1977-07-27 |
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Legal Events
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NUG | Patent has lapsed |
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