SE7508332L - Sett att framstella 3-kinolin-karboxylsyraderivat och anvendning derav som lekemedel. - Google Patents

Sett att framstella 3-kinolin-karboxylsyraderivat och anvendning derav som lekemedel.

Info

Publication number
SE7508332L
SE7508332L SE7508332A SE7508332A SE7508332L SE 7508332 L SE7508332 L SE 7508332L SE 7508332 A SE7508332 A SE 7508332A SE 7508332 A SE7508332 A SE 7508332A SE 7508332 L SE7508332 L SE 7508332L
Authority
SE
Sweden
Prior art keywords
quinoline
group
carboxylic acid
drug
preparing
Prior art date
Application number
SE7508332A
Other languages
English (en)
Other versions
SE425244B (sv
Inventor
F Clemence
R Deraedt
A Allais
Martret O Le
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of SE7508332L publication Critical patent/SE7508332L/sv
Publication of SE425244B publication Critical patent/SE425244B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE7508332A 1974-08-13 1975-07-22 Sett att framstella 4-hydroxi-3-kinolin-karboxamidderivat SE425244B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7428038A FR2281761A1 (fr) 1974-08-13 1974-08-13 Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament

Publications (2)

Publication Number Publication Date
SE7508332L true SE7508332L (sv) 1976-02-16
SE425244B SE425244B (sv) 1982-09-13

Family

ID=9142372

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7508332A SE425244B (sv) 1974-08-13 1975-07-22 Sett att framstella 4-hydroxi-3-kinolin-karboxamidderivat

Country Status (21)

Country Link
US (1) US3992540A (sv)
JP (1) JPS5925793B2 (sv)
AR (1) AR208323A1 (sv)
AT (1) AT340928B (sv)
BE (1) BE832332A (sv)
CA (1) CA1055499A (sv)
CH (1) CH614953A5 (sv)
DD (1) DD122972A5 (sv)
DE (1) DE2536206C2 (sv)
DK (1) DK142319B (sv)
ES (1) ES440079A1 (sv)
FR (1) FR2281761A1 (sv)
GB (1) GB1484787A (sv)
HU (1) HU170060B (sv)
IE (1) IE41841B1 (sv)
IL (1) IL47820A (sv)
LU (1) LU73193A1 (sv)
NL (1) NL7509625A (sv)
SE (1) SE425244B (sv)
SU (1) SU566522A3 (sv)
ZA (1) ZA754905B (sv)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2340735A1 (fr) * 1976-02-11 1977-09-09 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2443467A1 (fr) * 1978-12-08 1980-07-04 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2482596A1 (fr) * 1980-05-19 1981-11-20 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur procede de preparation et leur application comme medicament
IE52670B1 (en) * 1981-03-03 1988-01-20 Leo Ab Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
HU190796B (en) * 1981-06-12 1986-11-28 Roussel Uclaf,Fr Process for producing n-dihydrothiazolyl-3-quinoline-carboxamide derivatives
FR2507602A1 (fr) * 1981-06-12 1982-12-17 Roussel Uclaf Nouveau derive dihydrothiazole de la quinoleine, ses sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2523130A1 (fr) * 1982-03-15 1983-09-16 Roussel Uclaf Nouveaux derives de la n-dihydrothiazolyl-3-quinoleine carboxamide, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2509728A1 (fr) * 1981-07-17 1983-01-21 Roussel Uclaf Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2537140B1 (fr) * 1982-12-07 1986-07-18 Roussel Uclaf Nouveaux derives de la 4-hydroxy-3-quinoleine carboxamide, leur sels, procede de preparation, application a titre de medicaments, et compositions les renfermant
FR2566405B1 (fr) * 1984-06-25 1986-09-26 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus
US4602014A (en) * 1984-07-09 1986-07-22 Ciba-Geigy Corporation Ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives as benzodiazepine receptor modulators
US4689182A (en) * 1985-12-20 1987-08-25 Warner-Lambert Company Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
US4990533A (en) * 1985-12-20 1991-02-05 Warner-Lambert Co. Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
DK1773816T3 (en) 2004-06-24 2015-01-26 Vertex Pharma Modulators of ATP-binding cassette transporters
US20090105272A1 (en) * 2005-12-24 2009-04-23 Grootenhuis Peter D J Prodrugs of modulators of ABC transporters
JP5409010B2 (ja) 2005-12-28 2014-02-05 バーテックス ファーマシューティカルズ インコーポレイテッド N−[2,4−ビス(1,1−ジメチルエチル)−5−ヒドロキシフェニル]−1,4−ジヒドロ−4−オキソキノリン−3−カルボキサミドの固体形態
NZ624460A (en) 2009-03-20 2015-12-24 Vertex Pharma Process for making modulators of cystic fibrosis transmembrane conductance regulator
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
CN104470518A (zh) 2012-02-27 2015-03-25 沃泰克斯药物股份有限公司 药物组合物及其施用
CA2963945C (en) 2014-10-07 2023-01-10 Vertex Pharmaceuticals Incorporated Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH71A (de) * 1888-11-15 1889-06-13 Th Hunziker Apparat zum Absticken verlängerter Nädlinge für Handstickmaschinen
US2798070A (en) * 1954-02-04 1957-07-02 Mcneilab Inc Quaternary quinoline carboxamide salts and method of preparing same
JPS4323948Y1 (sv) * 1965-03-06 1968-10-09
US3524858A (en) * 1967-05-18 1970-08-18 Warner Lambert Pharmaceutical 1,4 - dihydro-1-substituted alkyl-6,7-methylenedioxy - 4 - oxoquinoline-3-carboxylic acid
US3496184A (en) * 1969-03-18 1970-02-17 Ciba Geigy Corp Cyclopropylmethoxy-3-quinoline carboxylic acids and esters

Also Published As

Publication number Publication date
DK142319C (sv) 1981-03-02
FR2281761B1 (sv) 1978-07-28
GB1484787A (en) 1977-09-08
AU8340875A (en) 1977-01-27
IL47820A (en) 1978-10-31
DE2536206A1 (de) 1976-03-04
JPS5925793B2 (ja) 1984-06-21
LU73193A1 (sv) 1976-08-13
NL7509625A (nl) 1976-02-17
IE41841B1 (en) 1980-04-09
ZA754905B (en) 1976-08-25
JPS5141366A (en) 1976-04-07
DK142319B (da) 1980-10-13
AT340928B (de) 1978-01-10
AR208323A1 (es) 1976-12-20
ATA630875A (de) 1977-05-15
CH614953A5 (sv) 1979-12-28
CA1055499A (en) 1979-05-29
IL47820A0 (en) 1975-10-15
DK366175A (sv) 1976-02-14
ES440079A1 (es) 1977-02-16
DE2536206C2 (de) 1984-07-19
SE425244B (sv) 1982-09-13
HU170060B (sv) 1977-03-28
SU566522A3 (ru) 1977-07-25
IE41841L (en) 1976-02-13
DD122972A5 (de) 1976-11-12
US3992540A (en) 1976-11-16
FR2281761A1 (fr) 1976-03-12
BE832332A (fr) 1976-02-12

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