SE405121B - Forfarande for framstellning av 2-(heteroaryl-metyl)-5-9beta-dialkyl-6,7-bensomorfaner eller deras syraadditionssalter - Google Patents

Forfarande for framstellning av 2-(heteroaryl-metyl)-5-9beta-dialkyl-6,7-bensomorfaner eller deras syraadditionssalter

Info

Publication number: SE405121B
Authority: SE; Sweden
Prior art keywords: benzomorphanes; 9beta; dialkyl; heteroaryl; methyl
Prior art date: 1972-06-19

Application number

SE7308564A

Other languages

English (en)

Swedish (sv)

Inventor

H Merz

A Langbein

K Stockhaus

H Wick

Original Assignee

Boehringer Sohn Ingelheim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-06-19

Filing date

1973-06-18

Publication date

1978-11-20

1973-06-18 Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim

1978-11-20 Publication of SE405121B publication Critical patent/SE405121B/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Steroid Compounds (AREA)

SE7308564A 1972-06-19 1973-06-18 Forfarande for framstellning av 2-(heteroaryl-metyl)-5-9beta-dialkyl-6,7-bensomorfaner eller deras syraadditionssalter SE405121B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2229695A DE2229695A1 (de)	1972-06-19	1972-06-19	2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung

Publications (1)

Publication Number	Publication Date
SE405121B true SE405121B (sv)	1978-11-20

Family

ID=5848060

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7308564A SE405121B (sv)	1972-06-19	1973-06-18	Forfarande for framstellning av 2-(heteroaryl-metyl)-5-9beta-dialkyl-6,7-bensomorfaner eller deras syraadditionssalter

Country Status (13)

Country	Link
US (1)	US3931194A (da)
JP (1)	JPS5711908B2 (da)
AT (6)	AT328627B (da)
BE (1)	BE801079A (da)
CH (9)	CH583228A5 (da)
DE (1)	DE2229695A1 (da)
DK (1)	DK136904C (da)
ES (8)	ES416037A1 (da)
FR (1)	FR2189056B1 (da)
GB (1)	GB1433817A (da)
NL (1)	NL7308483A (da)
NO (1)	NO137694C (da)
SE (1)	SE405121B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2437610A1 (de) *	1974-08-05	1976-02-26	Boehringer Sohn Ingelheim	Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
GB1575009A (en) *	1976-06-21	1980-09-17	Acf Chemiefarma Nv	6,7-benzomorphan derivatives
JPS63177704A (ja) *	1987-01-16	1988-07-21	松山株式会社	農作業機連結装置
ES2395081T3 (es)	2007-07-26	2013-02-08	Vitae Pharmaceuticals, Inc.	Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
TW200927115A (en) *	2007-11-16	2009-07-01	Boehringer Ingelheim Int	Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
EP2229368A1 (en)	2007-12-11	2010-09-22	Vitae Pharmaceuticals, Inc.	Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en)	2008-01-07	2009-08-16	Vitae Pharmaceuticals Inc	Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja)	2008-01-24	2014-05-14	ヴァイティーファーマシューティカルズ，インコーポレイテッド	１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
ATE531696T1 (de) *	2008-02-12	2011-11-15	Boehringer Ingelheim Int	Harnstoff-derivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung
WO2009102460A2 (en)	2008-02-15	2009-08-20	Vitae Pharmaceuticals, Inc.	Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2291370B1 (en)	2008-05-01	2013-11-27	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134400A1 (en)	2008-05-01	2009-11-05	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001058A1 (es)	2008-05-01	2010-09-10	Vitae Pharmaceuticals Inc	Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
EP2288596B1 (en)	2008-05-13	2016-11-30	Boehringer Ingelheim International GmbH	Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
CA2730499A1 (en)	2008-07-25	2010-01-28	Boehringer Ingelheim International Gmbh	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2729998A1 (en)	2008-07-25	2010-01-28	Boehringer Ingelheim International Gmbh	Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr)	2009-04-30	2012-04-02	Boehringer Ingelheim Int	Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
WO2011011123A1 (en)	2009-06-11	2011-01-27	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
UY33001A (es)	2009-11-06	2011-05-31	Boehringer Ingelheim Int	Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
JP5860042B2 (ja)	2010-06-16	2016-02-16	ヴァイティーファーマシューティカルズ，インコーポレイテッド	置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh)	2010-11-05	2016-06-11	百靈佳殷格翰國際股份有限公司	六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja)	2011-08-17	2014-09-22	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	インデノピリジン誘導体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1281227A (fr) *	1958-09-22	1962-01-12	Smith Kline French Lab	Perfectionnements apportés aux procédés pour la préparation de dérivés d'aralcoylbenzomorphane
BE582575A (da) *	1958-09-22
CS166804B2 (da) *	1971-02-08	1976-03-29	Boehringer Sohn Ingelheim
SE392895B (sv) *	1971-08-24	1977-04-25	Sumitomo Chemical Co	Forfarande for framstellning av bensomorfanderivat och deras salter

1972
- 1972-06-19 DE DE2229695A patent/DE2229695A1/de not_active Withdrawn
1973
- 1973-06-05 US US05/367,114 patent/US3931194A/en not_active Expired - Lifetime
- 1973-06-06 AT AT489474*7A patent/AT328627B/de not_active IP Right Cessation
- 1973-06-06 AT AT489874*7A patent/AT329199B/de not_active IP Right Cessation
- 1973-06-06 AT AT489774*7A patent/AT328628B/de not_active IP Right Cessation
- 1973-06-06 AT AT490074*7A patent/AT328629B/de not_active IP Right Cessation
- 1973-06-06 AT AT489974*7A patent/AT329200B/de not_active IP Right Cessation
- 1973-06-06 AT AT494373A patent/AT325218B/de not_active IP Right Cessation
- 1973-06-14 CH CH1040876A patent/CH583228A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041176A patent/CH582697A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH864373A patent/CH583227A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041376A patent/CH582698A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041576A patent/CH583231A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041076A patent/CH583230A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041276A patent/CH589648A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041476A patent/CH589649A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1040976A patent/CH583229A5/xx not_active IP Right Cessation
- 1973-06-18 JP JP6863473A patent/JPS5711908B2/ja not_active Expired
- 1973-06-18 BE BE132406A patent/BE801079A/xx unknown
- 1973-06-18 NO NO2518/73A patent/NO137694C/no unknown
- 1973-06-18 ES ES416037A patent/ES416037A1/es not_active Expired
- 1973-06-18 SE SE7308564A patent/SE405121B/xx unknown
- 1973-06-18 DK DK336173A patent/DK136904C/da active
- 1973-06-18 GB GB2886973A patent/GB1433817A/en not_active Expired
- 1973-06-19 FR FR7322249A patent/FR2189056B1/fr not_active Expired
- 1973-06-19 NL NL7308483A patent/NL7308483A/xx not_active Application Discontinuation
1974
- 1974-10-30 ES ES431511A patent/ES431511A1/es not_active Expired
- 1974-10-30 ES ES431514A patent/ES431514A1/es not_active Expired
- 1974-10-30 ES ES431513A patent/ES431513A1/es not_active Expired
- 1974-10-30 ES ES0431516A patent/ES431516A1/es not_active Expired
- 1974-10-30 ES ES431510A patent/ES431510A1/es not_active Expired
- 1974-10-30 ES ES431515A patent/ES431515A1/es not_active Expired
- 1974-10-30 ES ES431512A patent/ES431512A1/es not_active Expired

Also Published As

Publication number	Publication date
AT329199B (de)	1976-04-26
CH582698A5 (da)	1976-12-15
NO137694C (no)	1978-04-05
CH583231A5 (da)	1976-12-31
ES431516A1 (es)	1976-11-16
AU5704673A (en)	1974-12-19
ES431515A1 (es)	1976-11-01
BE801079A (fr)	1973-12-18
NO137694B (no)	1977-12-27
AT329200B (de)	1976-04-26
ES431511A1 (es)	1976-11-01
ES431512A1 (es)	1976-11-01
CH583229A5 (da)	1976-12-31
ES431510A1 (es)	1976-11-01
CH582697A5 (da)	1976-12-15
AT328628B (de)	1976-03-25
CH583227A5 (da)	1976-12-31
CH583228A5 (da)	1976-12-31
ATA489774A (de)	1975-06-15
DE2229695A1 (de)	1974-01-31
US3931194A (en)	1976-01-06
AT325218B (de)	1975-10-10
DK136904B (da)	1977-12-12
GB1433817A (en)	1976-04-28
JPS4961170A (da)	1974-06-13
ATA489874A (de)	1975-07-15
ES431513A1 (es)	1976-11-01
FR2189056B1 (da)	1976-10-22
ATA490074A (de)	1975-06-15
DK136904C (da)	1978-06-26
NL7308483A (da)	1973-12-21
FR2189056A1 (da)	1974-01-25
AT328627B (de)	1976-03-25
ES431514A1 (es)	1976-11-01
JPS5711908B2 (da)	1982-03-08
ES416037A1 (es)	1976-02-16
ATA489974A (de)	1975-07-15
CH589648A5 (da)	1977-07-15
AT328629B (de)	1976-03-25
CH589649A5 (da)	1977-07-15
ATA489474A (de)	1975-06-15
CH583230A5 (da)	1976-12-31

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