SE385904B - Forfarande for framstellning av 21-adamantoaterna av berametason och dess 9alfa-klor-analog - Google Patents

Forfarande for framstellning av 21-adamantoaterna av berametason och dess 9alfa-klor-analog

Info

Publication number
SE385904B
SE385904B SE7208817A SE881772A SE385904B SE 385904 B SE385904 B SE 385904B SE 7208817 A SE7208817 A SE 7208817A SE 881772 A SE881772 A SE 881772A SE 385904 B SE385904 B SE 385904B
Authority
SE
Sweden
Prior art keywords
berametason
adamantoats
9alfa
procedure
preparation
Prior art date
Application number
SE7208817A
Other languages
English (en)
Inventor
G H Phillipps
A F English
Original Assignee
Gloxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gloxo Lab Ltd filed Critical Gloxo Lab Ltd
Publication of SE385904B publication Critical patent/SE385904B/sv

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7208817A 1971-07-05 1972-07-04 Forfarande for framstellning av 21-adamantoaterna av berametason och dess 9alfa-klor-analog SE385904B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3134971A GB1391443A (en) 1971-07-05 1971-07-05 Ester of betamethasone and its 9alpha-chloro analogue

Publications (1)

Publication Number Publication Date
SE385904B true SE385904B (sv) 1976-07-26

Family

ID=10321802

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7208817A SE385904B (sv) 1971-07-05 1972-07-04 Forfarande for framstellning av 21-adamantoaterna av berametason och dess 9alfa-klor-analog

Country Status (17)

Country Link
JP (1) JPS5644079B1 (sv)
AR (2) AR194120A1 (sv)
AU (1) AU464251B2 (sv)
BE (1) BE785812A (sv)
CA (1) CA983919A (sv)
CH (1) CH609065A5 (sv)
DE (1) DE2232827A1 (sv)
DK (1) DK131474B (sv)
FR (1) FR2144761B1 (sv)
GB (1) GB1391443A (sv)
IE (1) IE36529B1 (sv)
IL (1) IL39821A (sv)
NL (1) NL169882C (sv)
NO (1) NO137754C (sv)
PH (1) PH13195A (sv)
SE (1) SE385904B (sv)
ZA (1) ZA724598B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5024427A (sv) * 1973-01-03 1975-03-15
SE418294B (sv) * 1974-03-27 1981-05-18 Plurichemie Anstalt Sett att framstella en 16alfa- eller 16beta-9alfa-klor eller -fluorsteroidester
JPS6163976U (sv) * 1984-10-01 1986-05-01
DK2444092T3 (en) 2008-05-28 2015-09-28 Reveragen Biopharma Inc Non-hormonal steroidmodulatorer of NF-? B for the treatment of disease
WO2011127048A2 (en) 2010-04-05 2011-10-13 Validus Biopharma NON-HORMONAL STEROID MODULATORS OF NF-ĸB FOR TREATMENT OF DISEASE
US10799514B2 (en) 2015-06-29 2020-10-13 Reveragen Biopharma, Inc. Non-hormonal steroid modulators of NF-kappa beta for treatment of disease
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Also Published As

Publication number Publication date
IL39821A (en) 1976-02-29
JPS5644079B1 (sv) 1981-10-16
CA983919A (en) 1976-02-17
NL169882C (nl) 1982-09-01
AU464251B2 (en) 1975-08-21
AR194553A1 (es) 1973-07-23
NL169882B (nl) 1982-04-01
ZA724598B (en) 1973-03-28
DK131474C (sv) 1975-12-08
NL7209345A (sv) 1973-01-09
FR2144761B1 (sv) 1976-03-05
BE785812A (fr) 1973-01-04
DK131474B (da) 1975-07-21
CH609065A5 (en) 1979-02-15
IL39821A0 (en) 1972-09-28
GB1391443A (en) 1975-04-23
AR194120A1 (es) 1973-06-22
AU4420572A (en) 1974-01-10
NO137754B (no) 1978-01-09
IE36529B1 (en) 1976-11-24
PH13195A (en) 1980-01-18
IE36529L (en) 1973-01-05
NO137754C (no) 1978-04-19
DE2232827A1 (de) 1973-01-18
FR2144761A1 (sv) 1973-02-16

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