SE0400021D0 - Non-nucleoside reverse transcriptase inhibitors - Google Patents
Non-nucleoside reverse transcriptase inhibitorsInfo
- Publication number
- SE0400021D0 SE0400021D0 SE0400021A SE0400021A SE0400021D0 SE 0400021 D0 SE0400021 D0 SE 0400021D0 SE 0400021 A SE0400021 A SE 0400021A SE 0400021 A SE0400021 A SE 0400021A SE 0400021 D0 SE0400021 D0 SE 0400021D0
- Authority
- SE
- Sweden
- Prior art keywords
- alkyl
- orx
- nrxrx
- reverse transcriptase
- transcriptase inhibitors
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compounds of the formula Z: where; A is CH or N; R1 is a substituent to a carbon atom in the ring containing A selected from -S(=O)pRa, where Ra is -C1-C4 alkyl, -ORx, -NRxRx, -NHNRxRx, - NHNHC(=O)ORx, -NRxOH; -C(=O)-Rb, where Rb is -CT-C4-alkyl, ORx, -NRxRx, -NHNRxRx, -NHC1-C3-alkyl-C(=O)Orx -NRxRc, where Rc is H, C1-C4 alkyl, -NRxRx; -C(=0)Rd, -CN, S(=O)pRx where Rd is Rd is C1-C4-alkyl, -ORx, -NRxRx C1-C3-alkyl-O-Cl-C3alkylC(=O)ORx, -C1-C3-alkyl-COORx; -C1-C3alkyl-OH or C1-C4 alkyl ethers or esters thereof (O-Cl-C3alkyl)q-O-Rx a 5 or 6 membered aromatic ring having 1-3 hetero atoms p is 1 or 2; Rx is independently selected from H, C1-C4 alkyl or acetyl; or a pair of Rx can together with the adjacent N atom form a ring; L is -0-, -S(=O),- or -CH2-, where r is 0, 1 or 2; R3-R7 are substituents as defined in the specification; X is -(CR8R8')n-D-(CR8R8')m-; D is a bond, -NR9-, -0-, -S-, -S(=0)- or -S(=0)2-; and pharmaceutically acceptable salts and prodrugs thereof, have utility as HIVantivirals.
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0400021A SE0400021D0 (en) | 2004-01-08 | 2004-01-08 | Non-nucleoside reverse transcriptase inhibitors |
AU2004312284A AU2004312284B2 (en) | 2004-01-08 | 2004-12-30 | Non-nucleotide reverse transcriptase inhibitors |
EA200601289A EA009700B1 (en) | 2004-01-08 | 2004-12-30 | Non-nucleotide reverse transcriptase inhibitors |
SG200809639-8A SG149070A1 (en) | 2004-01-08 | 2004-12-30 | Non-nucleotide reverse transcriptase inhibitors |
EP04809207A EP1701942B1 (en) | 2004-01-08 | 2004-12-30 | Non-nucleotide reverse transcriptase inhibitors |
CN2004800423227A CN1926108B (en) | 2004-01-08 | 2004-12-30 | Non-nucleotide reverse transcriptase inhibitors |
CA2550187A CA2550187C (en) | 2004-01-08 | 2004-12-30 | Non-nucleoside reverse transcriptase inhibitors |
DK04809207.6T DK1701942T3 (en) | 2004-01-08 | 2004-12-30 | Non-nucleotide reverse transcriptase inhibitors |
US10/584,933 US7915295B2 (en) | 2004-01-08 | 2004-12-30 | Non-nucleotide reverse transcriptase inhibitors |
PCT/SE2004/002034 WO2005066131A1 (en) | 2004-01-08 | 2004-12-30 | Non-nucleotide reverse transcriptase inhibitors |
NZ548367A NZ548367A (en) | 2004-01-08 | 2004-12-30 | Non-nucleoside reverse transcriptase inhibitors |
JP2006549182A JP4762917B2 (en) | 2004-01-08 | 2004-12-30 | Non-nucleoside reverse transcriptase inhibitors |
BRPI0418306A BRPI0418306B8 (en) | 2004-01-08 | 2004-12-30 | compound n-[(1s,1ar,7br)-4,7-difluoro-1,1a,2,7b-tetrahydrocyclopropa[c]chromen-1-yl]-n-[5-(4-(sulfonamido)phenoxy )-2-pyridinyl]urea, pharmaceutical composition and use of said compound for prophylaxis or treatment of HIV-1 infections |
ES04809207T ES2337794T3 (en) | 2004-01-08 | 2004-12-30 | NON-NUCLEOSIDE INHIBITORS OF THE REVERSE TRANSCRIPT. |
AT04809207T ATE451357T1 (en) | 2004-01-08 | 2004-12-30 | NON-NUCLEOTIDE REVERSE TRANSCRIPTASE INHIBITORS |
DE602004024584T DE602004024584D1 (en) | 2004-01-08 | 2004-12-30 | INHIBITORS OF THE NON-NUCLEOTIDIC REVERSE TRANSCRIPTASE |
ZA200605395A ZA200605395B (en) | 2004-01-08 | 2006-06-29 | Non-nucleotide reverse transcriptase inhibitors |
IL176740A IL176740A (en) | 2004-01-08 | 2006-07-06 | Non-nucleotide reverse transcriptase inhibitors, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for the prophylaxis or treatment of hiv-1 infections |
HK07109407.1A HK1101400A1 (en) | 2004-01-08 | 2007-08-29 | Non-nucleotide reverse transcriptase inhibitors |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0400021A SE0400021D0 (en) | 2004-01-08 | 2004-01-08 | Non-nucleoside reverse transcriptase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0400021D0 true SE0400021D0 (en) | 2004-01-08 |
Family
ID=31493006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0400021A SE0400021D0 (en) | 2004-01-08 | 2004-01-08 | Non-nucleoside reverse transcriptase inhibitors |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN1926108B (en) |
SE (1) | SE0400021D0 (en) |
ZA (1) | ZA200605395B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105693725A (en) * | 2016-03-22 | 2016-06-22 | 河南师范大学 | Method for synthesizing chiral ternary purine carbocyclic nucleoside analogue through intramolecular asymmetric cycloaddition |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0100733D0 (en) * | 2001-03-05 | 2001-03-05 | Medivir Ab | Non-nucleoside reverse transcriptase inhibitors |
-
2004
- 2004-01-08 SE SE0400021A patent/SE0400021D0/en unknown
- 2004-12-30 CN CN2004800423227A patent/CN1926108B/en not_active Expired - Fee Related
-
2006
- 2006-06-29 ZA ZA200605395A patent/ZA200605395B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200605395B (en) | 2007-04-25 |
CN1926108A (en) | 2007-03-07 |
CN1926108B (en) | 2010-06-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA200602060A1 (en) | DERIVATIVES PYRROLIDIN-2-SHE AND PIPERIDIN-2-SHE USED AS INHIBITORS 11-BETA-HYDROXYSTEROID-DEGYDROGENASE | |
HK1101400A1 (en) | Non-nucleotide reverse transcriptase inhibitors | |
NO20080738L (en) | Methods of neuroprotection | |
ZA200708159B (en) | 1-Acetic acid-indole derivatives with PDG2 antagonist activity | |
BRPI0518068A (en) | compound or a pharmaceutically acceptable salt or ester thereof, pharmaceutical composition, aurora a selective inhibitor, anti-tumor agent, and combined preparation | |
ME01421B (en) | 5-substituted quinazolinone derivatives as antitumor agents | |
JP2008525416A5 (en) | ||
JP2012522729A5 (en) | ||
RS52999B (en) | Bis(thio-hydrazide amide) salts for treatment of cancers | |
NO20071921L (en) | Methods for treating epileptogenesis and epilepsy | |
TW200607808A (en) | Pyrido-pyrimidine derivatives, preparation thereof and application thereof | |
MX360667B (en) | Ethynyl derivatives as mglur5 allosteric modulators. | |
TW200744575A (en) | Methods of treating epileptogenesis | |
EA200801536A1 (en) | NEW TIENOPYRESULPHONE DERIVATIVES | |
TW200745104A (en) | Multikinase inhibitor | |
HRP20040230B1 (en) | Muscarinic agonists | |
WO2009007536A3 (en) | Derivatives of 7-alkynyl-1,8-naphthyridones, preparation method thereof and use of same in therapeutics | |
MY140666A (en) | Biotinylated hexadecasaccharides, preparation and use thereof | |
BRPI0516112A (en) | methods for neuroprotection | |
EP1655291A4 (en) | Compounds having thrombopoietin receptor agonism | |
EA201101298A1 (en) | ADDITIVE SOLOMETAMINE SALTS WITH DERIVATIVES OF ABABYPHENYLAMINOBENZOIC ACID AS DHODH INHIBITORS | |
WO2008060787A3 (en) | Methods for treatment of cochlear and vestibular disorders | |
SE0400021D0 (en) | Non-nucleoside reverse transcriptase inhibitors | |
CO5170535A1 (en) | DERIVATIVES OF N- [2- (4-AMINOPHENYL) ETHYL] 2,3-DIHIDRO-1,4- BENZODIOXIN-2-METHANAMINE, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS | |
TW200504086A (en) | Novel bismuth compound, process of producing the same, and process of producing a film |