SE0100472D0 - Nya metalloproteaser som har trombospondindomäner och nukleinsyrakompositioner som kodar för dessa - Google Patents
Nya metalloproteaser som har trombospondindomäner och nukleinsyrakompositioner som kodar för dessaInfo
- Publication number
- SE0100472D0 SE0100472D0 SE0100472A SE0100472A SE0100472D0 SE 0100472 D0 SE0100472 D0 SE 0100472D0 SE 0100472 A SE0100472 A SE 0100472A SE 0100472 A SE0100472 A SE 0100472A SE 0100472 D0 SE0100472 D0 SE 0100472D0
- Authority
- SE
- Sweden
- Prior art keywords
- nucleic acid
- acid compositions
- applications
- metalloproteases
- thrombospondome
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000005741 Metalloproteases Human genes 0.000 title abstract 2
- 108010006035 Metalloproteases Proteins 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000016284 Aggrecans Human genes 0.000 abstract 1
- 108010067219 Aggrecans Proteins 0.000 abstract 1
- 102000002938 Thrombospondin Human genes 0.000 abstract 1
- 108060008245 Thrombospondin Proteins 0.000 abstract 1
- 108010003059 aggrecanase Proteins 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- GUGNSJAORJLKGP-UHFFFAOYSA-K sodium 8-methoxypyrene-1,3,6-trisulfonate Chemical compound [Na+].[Na+].[Na+].C1=C2C(OC)=CC(S([O-])(=O)=O)=C(C=C3)C2=C2C3=C(S([O-])(=O)=O)C=C(S([O-])(=O)=O)C2=C1 GUGNSJAORJLKGP-UHFFFAOYSA-K 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18415200P | 2000-02-18 | 2000-02-18 | |
FR0111527A FR2821085A1 (fr) | 2000-02-18 | 2001-09-06 | Nouvelles metalloproteases possedant des domaines thrombospondine et compositions d'acides nucleiques les codant |
Publications (2)
Publication Number | Publication Date |
---|---|
SE0100472D0 true SE0100472D0 (sv) | 2001-02-14 |
SE0100472L SE0100472L (sv) | 2001-08-19 |
Family
ID=26213171
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0100472A SE0100472L (sv) | 2000-02-18 | 2001-02-14 | Nya metalloproteaser som har trombospondindomäner och nukleinsyrakompositioner som kodar för dessa |
Country Status (8)
Country | Link |
---|---|
US (1) | US20020107361A1 (sv) |
JP (1) | JP2001286289A (sv) |
AU (1) | AU2303301A (sv) |
DE (1) | DE10107360A1 (sv) |
FR (2) | FR2806738A1 (sv) |
GB (1) | GB2361702A (sv) |
IT (1) | ITTO20010138A1 (sv) |
SE (1) | SE0100472L (sv) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1290195A2 (en) * | 2000-05-15 | 2003-03-12 | Millennium Pharmaceuticals, Inc. | 33428, a human metalloprotease family member and uses thereof |
NL1022371C2 (nl) * | 2003-01-13 | 2003-11-18 | Hoffmann La Roche | Nieuwe metallo-proteasen met trombospondine domeinen en daarvoor coderende nucle´nezuur samenstellingen. |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6451575B1 (en) * | 1997-07-25 | 2002-09-17 | Bristol-Myers Squibb Pharma Company | Aggrecan degrading metallo proteases |
WO2000053774A2 (en) * | 1999-03-08 | 2000-09-14 | Neurocrine Biosciences, Inc. | Metalloproteinases and methods of use therefor |
JP2004507202A (ja) * | 1999-03-31 | 2004-03-11 | キュラジェン コーポレイション | ポリペプチドをコードするオープンリーディングフレームを含む核酸;「orfx」 |
JP2001008687A (ja) * | 1999-06-25 | 2001-01-16 | Yamanouchi Pharmaceut Co Ltd | 新規金属プロテアーゼ及び該金属プロテアーゼ遺伝子 |
US6391610B1 (en) * | 1999-08-06 | 2002-05-21 | The Cleveland Clinic Foundation | Nucleic acids encoding zinc metalloproteases |
US6649399B2 (en) * | 1999-12-09 | 2003-11-18 | Lexicon Genetics Incorporated | Human proteases and polynucleotides encoding the same |
EP1136547A3 (en) * | 2000-03-22 | 2002-09-25 | Pfizer Products Inc. | Adamts polypeptides, nucleic acids encoding them, and uses thereof |
-
2001
- 2001-02-14 SE SE0100472A patent/SE0100472L/sv unknown
- 2001-02-16 IT IT2001TO000138A patent/ITTO20010138A1/it unknown
- 2001-02-16 FR FR0102142A patent/FR2806738A1/fr active Pending
- 2001-02-16 AU AU23033/01A patent/AU2303301A/en not_active Abandoned
- 2001-02-16 DE DE10107360A patent/DE10107360A1/de not_active Withdrawn
- 2001-02-16 GB GB0103914A patent/GB2361702A/en not_active Withdrawn
- 2001-02-16 US US09/788,043 patent/US20020107361A1/en not_active Abandoned
- 2001-02-19 JP JP2001042598A patent/JP2001286289A/ja active Pending
- 2001-09-06 FR FR0111527A patent/FR2821085A1/fr active Pending
Also Published As
Publication number | Publication date |
---|---|
DE10107360A1 (de) | 2001-09-06 |
ITTO20010138A0 (it) | 2001-02-16 |
GB2361702A (en) | 2001-10-31 |
JP2001286289A (ja) | 2001-10-16 |
FR2821085A1 (fr) | 2002-08-23 |
AU2303301A (en) | 2001-08-23 |
US20020107361A1 (en) | 2002-08-08 |
GB0103914D0 (en) | 2001-04-04 |
FR2806738A1 (fr) | 2001-09-28 |
SE0100472L (sv) | 2001-08-19 |
ITTO20010138A1 (it) | 2002-08-16 |
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