SE0003429L - Komposition och metod för framställning av mikropartiklar av vattenolösliga ämnen. - Google Patents
Komposition och metod för framställning av mikropartiklar av vattenolösliga ämnen.Info
- Publication number
- SE0003429L SE0003429L SE0003429A SE0003429A SE0003429L SE 0003429 L SE0003429 L SE 0003429L SE 0003429 A SE0003429 A SE 0003429A SE 0003429 A SE0003429 A SE 0003429A SE 0003429 L SE0003429 L SE 0003429L
- Authority
- SE
- Sweden
- Prior art keywords
- micron
- water
- block copolymer
- particles
- stabilization
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/926—Topical chemical, e.g. cosmetic or sunscreen
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7980998P | 1998-03-30 | 1998-03-30 | |
PCT/US1999/006746 WO1999049846A2 (en) | 1998-03-30 | 1999-03-29 | Compositions containing microparticles of water-insoluble substances and method for their preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
SE0003429D0 SE0003429D0 (sv) | 2000-09-26 |
SE0003429L true SE0003429L (sv) | 2000-11-23 |
Family
ID=22152962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0003429A SE0003429L (sv) | 1998-03-30 | 2000-09-26 | Komposition och metod för framställning av mikropartiklar av vattenolösliga ämnen. |
Country Status (14)
Country | Link |
---|---|
US (1) | US6387409B1 (de) |
EP (1) | EP1067914B1 (de) |
JP (2) | JP4709378B2 (de) |
KR (1) | KR100628341B1 (de) |
CN (1) | CN1303278B (de) |
AT (1) | ATE318132T1 (de) |
AU (1) | AU761205B2 (de) |
CA (1) | CA2326456C (de) |
DE (1) | DE69929959T2 (de) |
ES (1) | ES2257041T3 (de) |
IL (3) | IL162023A0 (de) |
SE (1) | SE0003429L (de) |
TW (1) | TWI267383B (de) |
WO (1) | WO1999049846A2 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6465016B2 (en) | 1996-08-22 | 2002-10-15 | Research Triangle Pharmaceuticals | Cyclosporiine particles |
AU761205B2 (en) * | 1998-03-30 | 2003-05-29 | Skyepharma Canada Inc. | Composition and method of preparing microparticles of water-insoluble substances |
DK1079808T3 (da) | 1998-05-29 | 2004-06-07 | Skyepharma Canada Inc | Præparater med termisk beskyttede mikropartikler og fremgangsmåde til slutdampsterilisering deraf |
KR20010075713A (ko) * | 1998-11-20 | 2001-08-09 | 추후제출 | 불용성 마이크로입자의 안정된 현탁액의 제조방법 |
US7939105B2 (en) | 1998-11-20 | 2011-05-10 | Jagotec Ag | Process for preparing a rapidly dispersing solid drug dosage form |
CA2383233C (en) * | 1999-09-21 | 2010-06-08 | Rtp Pharma Inc. | Surface modified particulate compositions of biologically active substances |
US7276249B2 (en) * | 2002-05-24 | 2007-10-02 | Elan Pharma International, Ltd. | Nanoparticulate fibrate formulations |
US20080241070A1 (en) * | 2000-09-21 | 2008-10-02 | Elan Pharma International Ltd. | Fenofibrate dosage forms |
US20030224058A1 (en) * | 2002-05-24 | 2003-12-04 | Elan Pharma International, Ltd. | Nanoparticulate fibrate formulations |
US9700866B2 (en) | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
US20030054042A1 (en) * | 2001-09-14 | 2003-03-20 | Elaine Liversidge | Stabilization of chemical compounds using nanoparticulate formulations |
US20060003012A9 (en) | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
CA2461349C (en) | 2001-09-26 | 2011-11-29 | Baxter International Inc. | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
US7112340B2 (en) * | 2001-10-19 | 2006-09-26 | Baxter International Inc. | Compositions of and method for preparing stable particles in a frozen aqueous matrix |
DE60325709D1 (de) | 2002-04-09 | 2009-02-26 | Flamel Tech Sa | Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen |
US20070264348A1 (en) * | 2002-05-24 | 2007-11-15 | Elan Pharma International, Ltd. | Nanoparticulate fibrate formulations |
FR2842736B1 (fr) | 2002-07-26 | 2005-07-22 | Flamel Tech Sa | Formulation pharmaceutique orale sous forme d'une pluralite de microcapsules permettant la liberation prolongee de principe(s) actif(s) peu soluble(s) |
FR2842735B1 (fr) | 2002-07-26 | 2006-01-06 | Flamel Tech Sa | Microcapsules a liberation modifiee de principes actifs peu solubles pour l'administration per os |
CN1243538C (zh) * | 2002-11-21 | 2006-03-01 | 武汉利元亨药物技术有限公司 | 熊果酸豆磷脂纳米粒冻干粉针及制备方法 |
GB0302672D0 (en) * | 2003-02-06 | 2003-03-12 | Astrazeneca Ab | Pharmaceutical formulations |
US6931888B2 (en) * | 2003-02-07 | 2005-08-23 | Ferro Corporation | Lyophilization method and apparatus for producing particles |
US20040178135A1 (en) * | 2003-03-13 | 2004-09-16 | Beplate Douglas K. | Filtering device incorporating nanoparticles |
AU2004240640A1 (en) * | 2003-05-19 | 2004-12-02 | Baxter International Inc. | Solid particles comprising an anticonvulsant or an immunosuppressive coated with one or more surface modifiers |
NZ546379A (en) * | 2003-10-31 | 2010-04-30 | Teva Pharma | Nanoparticles for drug delivery |
US20060141049A1 (en) * | 2003-11-12 | 2006-06-29 | Allergan, Inc. | Triamcinolone compositions for intravitreal administration to treat ocular conditions |
US20050101582A1 (en) | 2003-11-12 | 2005-05-12 | Allergan, Inc. | Compositions and methods for treating a posterior segment of an eye |
US20070224278A1 (en) * | 2003-11-12 | 2007-09-27 | Lyons Robert T | Low immunogenicity corticosteroid compositions |
WO2005072701A1 (en) | 2004-01-20 | 2005-08-11 | Allergan, Inc. | Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid |
US20050170063A1 (en) * | 2004-01-29 | 2005-08-04 | Lalit Chordia | Production of powder and viscous material |
US8119154B2 (en) * | 2004-04-30 | 2012-02-21 | Allergan, Inc. | Sustained release intraocular implants and related methods |
US8147865B2 (en) * | 2004-04-30 | 2012-04-03 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
AU2005271700B2 (en) * | 2004-07-12 | 2010-11-11 | Allergan, Inc. | Opthalmic compositions and methods for treating ophthalmic conditions |
WO2006043965A1 (en) * | 2004-10-14 | 2006-04-27 | Allergan, Inc. | Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods |
JPWO2006057429A1 (ja) * | 2004-11-24 | 2008-06-05 | ナノキャリア株式会社 | ブロックコポリマーのモーフォロジーの変化方法 |
WO2006138202A2 (en) * | 2005-06-14 | 2006-12-28 | Baxter International Inc. | Pharmaceutical formulations for minimizing drug-drug interactions |
WO2007008697A2 (en) * | 2005-07-08 | 2007-01-18 | University Of Chicago | Compositions and methods for refolding of denatured proteins |
BRPI0618661A2 (pt) * | 2005-11-15 | 2011-09-06 | Baxter Int | composições de inibidores de lipoxigenase |
WO2008080047A2 (en) * | 2006-12-23 | 2008-07-03 | Baxter International Inc. | Magnetic separation of fine particles from compositions |
US20080293814A1 (en) * | 2007-05-22 | 2008-11-27 | Deepak Tiwari | Concentrate esmolol |
US8426467B2 (en) * | 2007-05-22 | 2013-04-23 | Baxter International Inc. | Colored esmolol concentrate |
US8722736B2 (en) * | 2007-05-22 | 2014-05-13 | Baxter International Inc. | Multi-dose concentrate esmolol with benzyl alcohol |
CA2695178C (en) * | 2007-07-31 | 2015-06-23 | Otsuka Pharmaceutical Co., Ltd. | Methods for producing aripiprazole suspension and freeze-dried formulation |
WO2009042114A2 (en) | 2007-09-21 | 2009-04-02 | The Johns Hopkins University | Phenazine derivatives and uses thereof |
CN103228266B (zh) | 2010-10-29 | 2017-11-14 | 健康科学西部大学 | 三元混合物制剂 |
WO2014004507A1 (en) * | 2012-06-27 | 2014-01-03 | Shell Oil Company | Fuel and engine oil composition and its use |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5091187A (en) | 1990-04-26 | 1992-02-25 | Haynes Duncan H | Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs |
US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
MX9201782A (es) | 1991-04-19 | 1992-10-01 | Sandoz Ag | Particulas de sustancias biologicamente activas, sustancialmente insolubles en agua, proceso para su produccion y composicion farmaceutica que las contiene. |
US5298262A (en) | 1992-12-04 | 1994-03-29 | Sterling Winthrop Inc. | Use of ionic cloud point modifiers to prevent particle aggregation during sterilization |
US5340564A (en) | 1992-12-10 | 1994-08-23 | Sterling Winthrop Inc. | Formulations comprising olin 10-G to prevent particle aggregation and increase stability |
US5336507A (en) | 1992-12-11 | 1994-08-09 | Sterling Winthrop Inc. | Use of charged phospholipids to reduce nanoparticle aggregation |
US5326552A (en) | 1992-12-17 | 1994-07-05 | Sterling Winthrop Inc. | Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants |
DE4440337A1 (de) | 1994-11-11 | 1996-05-15 | Dds Drug Delivery Services Ges | Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit |
US5569448A (en) | 1995-01-24 | 1996-10-29 | Nano Systems L.L.C. | Sulfated nonionic block copolymer surfactants as stabilizer coatings for nanoparticle compositions |
ATE198148T1 (de) * | 1995-02-06 | 2001-01-15 | Elan Pharma Int Ltd | Formulierungen von verbindungen als nanopartikel dispergiert in verdaubaren ölen oder fettsäuren |
US5510118A (en) | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
ES2306452T3 (es) * | 1995-10-17 | 2008-11-01 | Jagotec Ag | Aporte de farmacos insolubles. |
US5686133A (en) | 1996-01-31 | 1997-11-11 | Port Systems, L.L.C. | Water soluble pharmaceutical coating and method for producing coated pharmaceuticals |
IL128632A (en) * | 1996-08-22 | 2003-03-12 | Rtp Pharma Corp | Compositions comprising microparticles of water-insoluble substances and method for preparing same |
AU1809499A (en) * | 1997-12-10 | 1999-06-28 | Awadhesh K. Mishra | Self-emulsifying fenofibrate formulations |
AU761205B2 (en) * | 1998-03-30 | 2003-05-29 | Skyepharma Canada Inc. | Composition and method of preparing microparticles of water-insoluble substances |
JPWO2013047199A1 (ja) * | 2011-09-30 | 2015-03-26 | Jx日鉱日石金属株式会社 | スパッタリングターゲット及びその製造方法 |
-
1999
- 1999-03-29 AU AU31185/99A patent/AU761205B2/en not_active Ceased
- 1999-03-29 AT AT99912926T patent/ATE318132T1/de not_active IP Right Cessation
- 1999-03-29 CN CN998067113A patent/CN1303278B/zh not_active Expired - Fee Related
- 1999-03-29 ES ES99912926T patent/ES2257041T3/es not_active Expired - Lifetime
- 1999-03-29 EP EP99912926A patent/EP1067914B1/de not_active Expired - Lifetime
- 1999-03-29 DE DE69929959T patent/DE69929959T2/de not_active Expired - Lifetime
- 1999-03-29 KR KR1020007010469A patent/KR100628341B1/ko not_active IP Right Cessation
- 1999-03-29 IL IL16202399A patent/IL162023A0/xx unknown
- 1999-03-29 IL IL13876599A patent/IL138765A0/xx active IP Right Grant
- 1999-03-29 WO PCT/US1999/006746 patent/WO1999049846A2/en not_active Application Discontinuation
- 1999-03-29 JP JP2000540812A patent/JP4709378B2/ja not_active Expired - Fee Related
- 1999-03-29 CA CA002326456A patent/CA2326456C/en not_active Expired - Fee Related
- 1999-05-14 TW TW088105042A patent/TWI267383B/zh not_active IP Right Cessation
-
2000
- 2000-01-04 US US09/477,351 patent/US6387409B1/en not_active Expired - Lifetime
- 2000-09-26 SE SE0003429A patent/SE0003429L/xx not_active Application Discontinuation
- 2000-09-28 IL IL138765A patent/IL138765A/en not_active IP Right Cessation
-
2010
- 2010-10-15 JP JP2010232130A patent/JP5539839B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU761205B2 (en) | 2003-05-29 |
WO1999049846A2 (en) | 1999-10-07 |
JP2011037889A (ja) | 2011-02-24 |
ES2257041T3 (es) | 2006-07-16 |
JP5539839B2 (ja) | 2014-07-02 |
ATE318132T1 (de) | 2006-03-15 |
CN1303278A (zh) | 2001-07-11 |
TWI267383B (en) | 2006-12-01 |
IL138765A0 (en) | 2001-10-31 |
EP1067914B1 (de) | 2006-02-22 |
IL138765A (en) | 2007-09-20 |
CA2326456C (en) | 2008-12-23 |
SE0003429D0 (sv) | 2000-09-26 |
DE69929959T2 (de) | 2006-11-02 |
CA2326456A1 (en) | 1999-10-07 |
US6387409B1 (en) | 2002-05-14 |
KR20010042103A (ko) | 2001-05-25 |
IL162023A0 (en) | 2005-11-20 |
KR100628341B1 (ko) | 2006-09-27 |
AU3118599A (en) | 1999-10-18 |
EP1067914A2 (de) | 2001-01-17 |
JP2002509876A (ja) | 2002-04-02 |
DE69929959D1 (de) | 2006-04-27 |
CN1303278B (zh) | 2010-06-23 |
WO1999049846A3 (en) | 1999-11-18 |
JP4709378B2 (ja) | 2011-06-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAV | Patent application has lapsed |