SA518400042B1 - مترافق من فيناستيريد مع ببتيد - Google Patents
مترافق من فيناستيريد مع ببتيدInfo
- Publication number
- SA518400042B1 SA518400042B1 SA518400042A SA518400042A SA518400042B1 SA 518400042 B1 SA518400042 B1 SA 518400042B1 SA 518400042 A SA518400042 A SA 518400042A SA 518400042 A SA518400042 A SA 518400042A SA 518400042 B1 SA518400042 B1 SA 518400042B1
- Authority
- SA
- Saudi Arabia
- Prior art keywords
- finasteride
- peptide
- hair loss
- composition
- linked
- Prior art date
Links
- DBEPLOCGEIEOCV-WSBQPABSSA-N finasteride Chemical compound N([C@@H]1CC2)C(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)NC(C)(C)C)[C@@]2(C)CC1 DBEPLOCGEIEOCV-WSBQPABSSA-N 0.000 title abstract 3
- 229960004039 finasteride Drugs 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 230000003779 hair growth Effects 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 230000003658 preventing hair loss Effects 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000001737 promoting effect Effects 0.000 abstract 2
- 201000004384 Alopecia Diseases 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 230000003676 hair loss Effects 0.000 abstract 1
- 208000024963 hair loss Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cosmetics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
يتعلق الاختراع الحالي بتركيبة لمنع تساقط الشعر و، بشكل أكثر تحديدا، إلى مركب له بنية حيث يتم ربط فيناستيريد finasteride وببتيد peptide خلال رابط تساهمي covalent bond وتركيبة صيدلانية pharmaceutical composition أو تركيبة تجميلية cosmetic composition لمنع تساقط الشعر أو تعزيز نمو الشعر تحتوي عليها. المركب وفقا للاختراع الحالي له بنية حيث يتم ربط فيناستيريد وببتيد خلال رابط تساهمي ممتاز في الأنشطة الفسيولوجية مثل تحسين تساقط الشعر، تعزيز نمو الشعر، تعزيز نمو الخلية، إلخ.، ممتاز في الثبات في الماء ونفاذية الجلد، وبالتالي يمكن استخدامها بفاعلية كتركيبة لمنع تساقط الشعر وتعزيز نمو الشعر. شكل1
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20160032988 | 2016-03-18 | ||
PCT/KR2016/005405 WO2017159922A1 (ko) | 2016-03-18 | 2016-05-20 | 피나스테라이드와 펩타이드의 결합체 |
Publications (1)
Publication Number | Publication Date |
---|---|
SA518400042B1 true SA518400042B1 (ar) | 2022-02-08 |
Family
ID=59852267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SA518400042A SA518400042B1 (ar) | 2016-03-18 | 2018-09-18 | مترافق من فيناستيريد مع ببتيد |
Country Status (17)
Country | Link |
---|---|
US (1) | US11357783B2 (ar) |
EP (1) | EP3431505B1 (ar) |
JP (2) | JP6835867B2 (ar) |
KR (1) | KR102160565B1 (ar) |
CN (1) | CN107428841B (ar) |
AU (1) | AU2016397332B2 (ar) |
BR (1) | BR112018068886A2 (ar) |
CA (1) | CA3018193C (ar) |
CL (1) | CL2018002629A1 (ar) |
EA (1) | EA039431B1 (ar) |
ES (1) | ES2928882T3 (ar) |
MX (1) | MX2018011209A (ar) |
MY (1) | MY189759A (ar) |
PH (1) | PH12018501993A1 (ar) |
SA (1) | SA518400042B1 (ar) |
WO (1) | WO2017159922A1 (ar) |
ZA (1) | ZA201806245B (ar) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111278420B (zh) * | 2017-09-18 | 2023-09-19 | 安尼根有限公司 | 活性物质-六肽复合体及包含其的化妆品组合物 |
KR20190065178A (ko) | 2017-12-01 | 2019-06-11 | 주식회사 굳티셀 | 탈모의 예방 또는 치료용 조성물 |
KR102221365B1 (ko) * | 2019-05-07 | 2021-03-02 | (주)케어젠 | 트롤록스-펩타이드 결합체 및 그의 용도 |
KR102157124B1 (ko) * | 2019-12-23 | 2020-09-18 | (주)인벤티지랩 | 피나스테라이드를 포함하는 서방성 주사용 조성물 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3596835B2 (ja) | 1996-08-13 | 2004-12-02 | 株式会社ノエビア | 養毛剤 |
US7060708B2 (en) | 1999-03-10 | 2006-06-13 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
EP2316468A1 (en) * | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
EP1660017A4 (en) | 2003-07-29 | 2011-03-09 | Signature R & D Holdings Llc | Amino acid PRODRUGS |
US8173840B2 (en) | 2003-07-29 | 2012-05-08 | Signature R&D Holdings, Llc | Compounds with high therapeutic index |
CN100415239C (zh) | 2005-05-16 | 2008-09-03 | 济南百诺医药科技开发有限公司 | 非那雄胺高浓度溶液及用途 |
KR100804494B1 (ko) | 2006-07-18 | 2008-02-20 | 김준현 | 악취 제거 장치 |
KR20080077762A (ko) | 2007-02-21 | 2008-08-26 | 주식회사 웰코스 | 탈모방지 및 모발생장 촉진 효과를 가지는 생약화장료조성물 |
KR101386570B1 (ko) | 2007-07-24 | 2014-04-21 | 엘지디스플레이 주식회사 | 액정표시장치 |
KR101021197B1 (ko) | 2008-04-11 | 2011-03-11 | (주)케어젠 | 성장인자―미미킹 펩타이드 및 그의 용도 |
WO2010072228A1 (en) | 2008-12-22 | 2010-07-01 | Xigen S.A. | Novel transporter constructs and transporter cargo conjugate molecules |
KR101163171B1 (ko) | 2009-01-20 | 2012-07-19 | (주)케어젠 | 노긴?유래 펩타이드 및 그의 용도 |
KR101198918B1 (ko) | 2009-09-01 | 2012-11-07 | (주)케어젠 | Wnt10?유래 펩타이드 및 그의 용도 |
HUE035584T2 (en) | 2011-01-21 | 2018-05-28 | Igisu Co Ltd | A therapeutic agent for the treatment of allopathy |
CN103596550A (zh) * | 2011-04-25 | 2014-02-19 | 朴俊炯 | 用于预防脱发和促进毛发生长的局部施用的组合物 |
KR101205209B1 (ko) | 2011-04-25 | 2012-11-27 | 박준형 | 탈모방지 및 발모촉진용 외용제 조성물 |
BR102012022034B1 (pt) | 2012-08-31 | 2020-02-18 | Biolab Sanus Farmacêutica Ltda. | Nanopartícula polimérica de finasterida, suspensão aquosa contendo a mesma, composição para tratamento de alopecia, processo de preparação de dita composição, e seu uso |
US9700633B2 (en) * | 2013-01-28 | 2017-07-11 | Jenkem Technology Co., Ltd., Tianjin Branch | Conjugates of water soluble polymer-amino acid oligopeptide-drug, preparation method and use thereof |
US20150118292A1 (en) * | 2013-10-24 | 2015-04-30 | Daniel Khesin | Compositions and methods for treatment of hair loss |
-
2016
- 2016-05-20 ES ES16894653T patent/ES2928882T3/es active Active
- 2016-05-20 KR KR1020187026417A patent/KR102160565B1/ko active IP Right Grant
- 2016-05-20 CN CN201680000881.4A patent/CN107428841B/zh active Active
- 2016-05-20 AU AU2016397332A patent/AU2016397332B2/en active Active
- 2016-05-20 MX MX2018011209A patent/MX2018011209A/es unknown
- 2016-05-20 MY MYPI2018703271A patent/MY189759A/en unknown
- 2016-05-20 EP EP16894653.1A patent/EP3431505B1/en active Active
- 2016-05-20 US US16/086,256 patent/US11357783B2/en active Active
- 2016-05-20 JP JP2018548657A patent/JP6835867B2/ja active Active
- 2016-05-20 WO PCT/KR2016/005405 patent/WO2017159922A1/ko active Application Filing
- 2016-05-20 EA EA201892112A patent/EA039431B1/ru unknown
- 2016-05-20 BR BR112018068886A patent/BR112018068886A2/pt active Search and Examination
- 2016-05-20 CA CA3018193A patent/CA3018193C/en active Active
-
2018
- 2018-09-13 CL CL2018002629A patent/CL2018002629A1/es unknown
- 2018-09-14 PH PH12018501993A patent/PH12018501993A1/en unknown
- 2018-09-17 ZA ZA2018/06245A patent/ZA201806245B/en unknown
- 2018-09-18 SA SA518400042A patent/SA518400042B1/ar unknown
-
2020
- 2020-11-06 JP JP2020186148A patent/JP2021011507A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3431505B1 (en) | 2022-09-07 |
EP3431505A4 (en) | 2019-01-23 |
ES2928882T3 (es) | 2022-11-23 |
CL2018002629A1 (es) | 2019-03-22 |
CA3018193A1 (en) | 2017-09-21 |
MX2018011209A (es) | 2019-05-16 |
US11357783B2 (en) | 2022-06-14 |
BR112018068886A2 (pt) | 2019-01-22 |
JP6835867B2 (ja) | 2021-02-24 |
PH12018501993A1 (en) | 2019-06-17 |
AU2016397332B2 (en) | 2020-04-30 |
JP2019512502A (ja) | 2019-05-16 |
US20200289526A1 (en) | 2020-09-17 |
AU2016397332A1 (en) | 2018-10-18 |
JP2021011507A (ja) | 2021-02-04 |
CA3018193C (en) | 2023-04-04 |
KR102160565B1 (ko) | 2020-09-28 |
EP3431505A1 (en) | 2019-01-23 |
CN107428841B (zh) | 2021-06-11 |
EA039431B1 (ru) | 2022-01-26 |
ZA201806245B (en) | 2019-07-31 |
KR20180112003A (ko) | 2018-10-11 |
WO2017159922A1 (ko) | 2017-09-21 |
MY189759A (en) | 2022-03-02 |
EA201892112A1 (ru) | 2019-03-29 |
CN107428841A (zh) | 2017-12-01 |
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