RU97108960A - METHOD AND DEVICE FOR ASEPTIC AND AUTOMATIC TRANSFER OF NON-SEALED PHARMACEUTICAL CONTAINERS - Google Patents

METHOD AND DEVICE FOR ASEPTIC AND AUTOMATIC TRANSFER OF NON-SEALED PHARMACEUTICAL CONTAINERS

Info

Publication number
RU97108960A
RU97108960A RU97108960/14A RU97108960A RU97108960A RU 97108960 A RU97108960 A RU 97108960A RU 97108960/14 A RU97108960/14 A RU 97108960/14A RU 97108960 A RU97108960 A RU 97108960A RU 97108960 A RU97108960 A RU 97108960A
Authority
RU
Russia
Prior art keywords
chamber
pharmaceutical
pharmaceutical containers
transfer
containers
Prior art date
Application number
RU97108960/14A
Other languages
Russian (ru)
Other versions
RU2179011C2 (en
Inventor
Ольссон Берт-Оке
Original Assignee
Астра Актиеболаг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9503102A external-priority patent/SE9503102D0/en
Application filed by Астра Актиеболаг filed Critical Астра Актиеболаг
Publication of RU97108960A publication Critical patent/RU97108960A/en
Application granted granted Critical
Publication of RU2179011C2 publication Critical patent/RU2179011C2/en

Links

Claims (11)

1. Способ для асептического и автоматического переноса незагерметизированных фармацевтических контейнеров (2), асептически загруженных фармацевтическим препаратом (5), от загрузочного устройства (6) к последующему участку (4), отличающийся тем, что включает следующие стадии:
а) введения стерильного инертного защитного газа (3) в переносную камеру (1),
b) вставки камеры (1) в загрузочное устройство (6),
с) введения фармацевтических контейнеров (2) в камеру (1) и закрывания камеры (1), и
d) транспортировки камеры (1) к последующему участку (4), на котором фармацевтические контейнеры (2) удаляют из камеры (1), причем защитный газ (3) непрерывно и равномерно распределяется в стадиях b)-d) над незакрытыми фармацевтическими контейнерами (2).1. A method for aseptic and automatic transfer of unsealed pharmaceutical containers (2), aseptically loaded with a pharmaceutical preparation (5), from a loading device (6) to a subsequent section (4), characterized in that it includes the following steps:
a) introducing a sterile inert protective gas (3) into a portable chamber (1),
b) inserting the camera (1) into the loading device (6),
c) introducing the pharmaceutical containers (2) into the chamber (1) and closing the chamber (1), and
d) transporting the chamber (1) to a subsequent section (4) in which the pharmaceutical containers (2) are removed from the chamber (1), the protective gas (3) being continuously and evenly distributed in steps b) to d) over the unclosed pharmaceutical containers ( 2). 2. Способ по п. 1, отличающийся тем, что азот, инертный газ или их смесь вводят в качестве защитного газа (3) в камеру (1). 2. The method according to p. 1, characterized in that nitrogen, an inert gas or a mixture thereof is introduced as a protective gas (3) into the chamber (1). 3. Способ по п. 1, отличающийся тем, что фармацевтические пузырьки, ампулы или бутылки (2), наполненные фармацевтическими препаратами (5), асептически переносят к последующему участку (4). 3. The method according to p. 1, characterized in that the pharmaceutical vials, ampoules or bottles (2) filled with pharmaceutical preparations (5) are aseptically transferred to the subsequent site (4). 4. Способ по п. 3, отличающийся тем, что фармацевтические пузырьки (2), содержащие раствор омепразола (5), асептически переносят к последующему участку (4). 4. The method according to p. 3, characterized in that the pharmaceutical vials (2) containing the omeprazole solution (5) are aseptically transferred to the subsequent site (4). 5. Способ по п. 1, отличающийся тем, что фармацевтические контейнеры (2) асептически переносят по меньшей мере к одному лиофилизатору (4). 5. The method according to p. 1, characterized in that the pharmaceutical containers (2) are aseptically transferred to at least one lyophilizer (4). 6. Способ по п. 1, отличающийся тем, что камеру (1) стерилизуют посредством фильтрации перед использованием. 6. The method according to p. 1, characterized in that the chamber (1) is sterilized by filtration before use. 7. Устройство переноса для асептического и автоматического переноса незагерметизированных фармацевтических контейнеров (2), асептически наполненных фармацевтическим препаратом (5), от загрузочного устройства (6) к последующему участку (4), причем это устройство переноса содержит транспортирующее средство (11), вертикально регулируемую платформу (12), расположенную на нем, и переносную и герметизируемую камеру (1), размещенную на платформе (12) и поддерживающую фармацевтические контейнеры (2) во время переноса, отличающееся тем, что камера (1) содержит
а) верхнюю часть (8), снабженную впускным отверстием (7) для защитного газа,
b) нижнюю часть (9), снабженную рамой (13) для поддерживания фармацевтических контейнеров (2) во время переноса и с закрываемым отверстием (14) для введения и удаления фармацевтических контейнеров (2), причем верхняя часть (8) и нижняя часть (9) разделены промежуточным, по существу горизонтальным распределителем потока (10) для равномерного распределения защитного газа (3) из верхней части (8) над фармацевтическими контейнерами (2) в нижнюю часть (9).7. A transfer device for aseptic and automatic transfer of unsealed pharmaceutical containers (2), aseptically filled with a pharmaceutical preparation (5), from a loading device (6) to a subsequent section (4), moreover, this transfer device contains a transporting means (11), vertically adjustable a platform (12) located on it, and a portable and pressurized chamber (1) placed on the platform (12) and supporting pharmaceutical containers (2) during transfer, characterized in that the chamber (1) contains INH
a) the upper part (8), equipped with an inlet (7) for the protective gas,
b) a lower part (9) provided with a frame (13) for supporting the pharmaceutical containers (2) during transfer and with a lockable hole (14) for introducing and removing the pharmaceutical containers (2), the upper part (8) and the lower part ( 9) are separated by an intermediate, essentially horizontal flow distributor (10) for uniform distribution of the protective gas (3) from the upper part (8) over the pharmaceutical containers (2) to the lower part (9). 8. Устройство переноса по п. 7, отличающееся тем, что распределитель потока (10) камеры (1) содержит перфорированные пластины и фильтр, выполненный из спекшихся пластиковых шариков, заключенный в виде слоя между ними. 8. The transfer device according to claim 7, characterized in that the flow distributor (10) of the chamber (1) contains perforated plates and a filter made of sintered plastic balls, enclosed as a layer between them. 9. Устройство переноса по п. 7, отличающееся тем, что рама (13) камеры (1) выполнена с возможностью поддержки около 400 фармацевтических контейнеров (2) во время переноса. 9. The transfer device according to claim 7, characterized in that the frame (13) of the chamber (1) is configured to support about 400 pharmaceutical containers (2) during transfer. 10. Устройство переноса по п. 7, отличающееся тем, что перенос фармацевтических контейнеров (2) в камере (1) управляется лазерно-направляющей системой управления для транспортировки средства (11). 10. The transfer device according to claim 7, characterized in that the transfer of the pharmaceutical containers (2) in the chamber (1) is controlled by a laser-guiding control system for transporting the means (11). 11. Асептический фармацевтический контейнер, обрабатываемый согласно способу по п. 1. 11. Aseptic pharmaceutical container processed according to the method of claim 1.
RU97108960/14A 1995-09-08 1996-09-06 Method and device for aseptic and automatic transfer of unsealed pharmaceutical containers RU2179011C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9503102-7 1995-09-08
SE9503102A SE9503102D0 (en) 1995-09-08 1995-09-08 Aseptic transfer

Publications (2)

Publication Number Publication Date
RU97108960A true RU97108960A (en) 1999-05-27
RU2179011C2 RU2179011C2 (en) 2002-02-10

Family

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Family Applications (1)

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RU97108960/14A RU2179011C2 (en) 1995-09-08 1996-09-06 Method and device for aseptic and automatic transfer of unsealed pharmaceutical containers

Country Status (26)

Country Link
US (2) US5799464A (en)
EP (1) EP0812177B1 (en)
JP (1) JP4087901B2 (en)
KR (1) KR100431230B1 (en)
CN (1) CN1121198C (en)
AT (1) ATE266993T1 (en)
AU (1) AU700700B2 (en)
BR (1) BR9606632A (en)
CA (1) CA2203252C (en)
CZ (1) CZ131797A3 (en)
DE (1) DE69632528T2 (en)
DK (1) DK0812177T3 (en)
EE (1) EE9700111A (en)
ES (1) ES2219695T3 (en)
HU (1) HUP9801286A3 (en)
IL (3) IL120692A (en)
IS (1) IS4465A (en)
NO (1) NO313321B1 (en)
NZ (1) NZ318109A (en)
PL (1) PL320349A1 (en)
PT (1) PT812177E (en)
RU (1) RU2179011C2 (en)
SE (1) SE9503102D0 (en)
SK (1) SK53497A3 (en)
TR (1) TR199700335T1 (en)
WO (1) WO1997009026A1 (en)

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