RU97100179A - MONOCLONAL ANTIBODY AGAINST CD44V6 - Google Patents
MONOCLONAL ANTIBODY AGAINST CD44V6Info
- Publication number
- RU97100179A RU97100179A RU97100179/04A RU97100179A RU97100179A RU 97100179 A RU97100179 A RU 97100179A RU 97100179/04 A RU97100179/04 A RU 97100179/04A RU 97100179 A RU97100179 A RU 97100179A RU 97100179 A RU97100179 A RU 97100179A
- Authority
- RU
- Russia
- Prior art keywords
- antibody
- antibody molecule
- molecule
- molecule according
- paragraphs
- Prior art date
Links
- 102000005614 monoclonal antibodies Human genes 0.000 title 1
- 108010045030 monoclonal antibodies Proteins 0.000 title 1
- 102000004965 antibodies Human genes 0.000 claims 24
- 108090001123 antibodies Proteins 0.000 claims 24
- 210000004408 Hybridomas Anatomy 0.000 claims 2
- 238000004166 bioassay Methods 0.000 claims 2
- 230000002285 radioactive Effects 0.000 claims 2
- 102100003735 CD44 Human genes 0.000 claims 1
- 101700078950 CD44 Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 230000035693 Fab Effects 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 108091006028 chimera Proteins 0.000 claims 1
- 239000000032 diagnostic agent Substances 0.000 claims 1
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 230000002255 enzymatic Effects 0.000 claims 1
- 230000002055 immunohistochemical Effects 0.000 claims 1
- 239000003547 immunosorbent Substances 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000006011 modification reaction Methods 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Claims (17)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEP4419913.9 | 1994-06-08 | ||
DE4419913 | 1994-06-08 | ||
DE19944431297 DE4431297A1 (en) | 1994-09-02 | 1994-09-02 | Antibody VFF-18 specific for epitope encoded by exon v6 of CD44 |
DEP4431297.0 | 1994-09-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU97100179A true RU97100179A (en) | 1999-03-20 |
RU2204606C2 RU2204606C2 (en) | 2003-05-20 |
Family
ID=25937246
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU97100179/13A RU2204606C2 (en) | 1994-06-08 | 1995-06-02 | Antibody vff-18 and its analogues |
Country Status (28)
Country | Link |
---|---|
US (1) | US5916561A (en) |
EP (1) | EP0765343B1 (en) |
JP (2) | JP3387929B2 (en) |
KR (2) | KR100379217B1 (en) |
CN (1) | CN1125083C (en) |
AT (1) | ATE197592T1 (en) |
BG (1) | BG64181B1 (en) |
BR (1) | BR9507964A (en) |
CA (1) | CA2192370A1 (en) |
CO (1) | CO4410258A1 (en) |
CZ (1) | CZ291274B6 (en) |
DE (1) | DE59508864D1 (en) |
DK (1) | DK0765343T3 (en) |
ES (1) | ES2151603T3 (en) |
FI (1) | FI964845A (en) |
GR (1) | GR3035388T3 (en) |
HK (1) | HK1011697A1 (en) |
HU (1) | HU220168B (en) |
NO (1) | NO317948B1 (en) |
NZ (1) | NZ288224A (en) |
PL (1) | PL190897B1 (en) |
PT (1) | PT765343E (en) |
RO (1) | RO118753B1 (en) |
RU (1) | RU2204606C2 (en) |
SI (1) | SI0765343T1 (en) |
SK (1) | SK282649B6 (en) |
UA (1) | UA58482C2 (en) |
WO (1) | WO1995033771A1 (en) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UY24389A1 (en) * | 1995-12-06 | 2001-10-25 | Karlsruhe Forschzent | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF FLAT EPITHELIUM CARCINOMA |
US6440733B1 (en) * | 1996-02-15 | 2002-08-27 | Chugai Seiyaku Kabushiki Kaisha | Monoclonal antibodies recognizing antigens on the surface of endothelial cells of tumor vessel |
DE19648209A1 (en) * | 1996-11-21 | 1998-05-28 | Boehringer Ingelheim Int | Procedure for tumor cell depletion of CD34-positive cells |
DE19708713C2 (en) * | 1997-03-04 | 2002-11-28 | Boehringer Ingelheim Int | Use of preparations containing anti-CD44 antibodies for the treatment of certain tumors and for the suppression of immune reactions |
WO1999064591A1 (en) * | 1998-06-08 | 1999-12-16 | Fuso Pharmaceutical Industries, Ltd. | Antibody against lar phosphatase subunit |
EP1097944B1 (en) * | 1998-07-10 | 2008-10-15 | Fuso Pharmaceutical Industries Ltd. | Antibody against protein tyrosine phosphatase intracellular domains |
US7947496B2 (en) | 1999-10-08 | 2011-05-24 | Hoffmann-La Roche Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US8048416B2 (en) * | 1999-10-08 | 2011-11-01 | Hoffmann-La Roche Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US20080124327A1 (en) * | 1999-10-08 | 2008-05-29 | Arius Research, Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US20050100542A1 (en) * | 1999-10-08 | 2005-05-12 | Young David S. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US7189397B2 (en) * | 1999-10-08 | 2007-03-13 | Arius Research Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US8071072B2 (en) * | 1999-10-08 | 2011-12-06 | Hoffmann-La Roche Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US20090004103A1 (en) * | 1999-10-08 | 2009-01-01 | Young David S F | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
CA2443437A1 (en) * | 2001-05-18 | 2002-11-28 | Boehringer Ingelheim International Gmbh | Antibodies specific for cd44v6 |
US6972324B2 (en) | 2001-05-18 | 2005-12-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Antibodies specific for CD44v6 |
US20030103985A1 (en) * | 2001-05-18 | 2003-06-05 | Boehringer Ingelheim International Gmbh | Cytotoxic CD44 antibody immunoconjugates |
WO2003018044A1 (en) * | 2001-08-24 | 2003-03-06 | Stroemblad Staffan | New drug |
US20040126379A1 (en) * | 2002-08-21 | 2004-07-01 | Boehringer Ingelheim International Gmbh | Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and chemotherapeutic agents |
AU2003272511A1 (en) * | 2002-09-13 | 2004-04-30 | Dyax Corporation | Cd44-binding ligands |
US20040120949A1 (en) * | 2002-11-08 | 2004-06-24 | Boehringer Ingelheim International Gmbh | Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and radiotherapy |
US20060140963A1 (en) * | 2003-04-14 | 2006-06-29 | Arius Research, Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD59 |
EP1806365A1 (en) | 2006-01-05 | 2007-07-11 | Boehringer Ingelheim International GmbH | Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them |
EP2266593A1 (en) | 2009-06-24 | 2010-12-29 | Karlsruher Institut für Technologie | Use of CD44v6 in the treatment of ophthalmic diseases |
BR112012003686B1 (en) * | 2009-08-19 | 2021-09-21 | Merck Patent Gmbh | MONOCLONAL ANTIBODIES, THEIR USE FOR DETECTION OF INTEGRIN COMPLEXES IN FFPE MATERIAL, AND POLYNUCLEOTIDE |
CN102337298B (en) * | 2011-08-19 | 2013-11-06 | 黄开红 | Immune nano-carrier for conveying siRNA (small interfering Ribonucleic Acid) and preparation method and application thereof |
ES2639855T3 (en) | 2013-12-23 | 2017-10-30 | Exchange Imaging Technologies Gmbh | Nanoparticle conjugated to CD44 binding peptides |
AU2018409898A1 (en) * | 2018-02-22 | 2020-09-24 | Multitude Inc. | Therapeutic antibody and uses thereof |
CN109593125A (en) * | 2018-12-12 | 2019-04-09 | 深圳市龙华区人民医院 | Antigen epitope polypeptide CD44-P1 and its application based on prostate cancer stem cells marker CD44 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0672130A1 (en) * | 1992-11-20 | 1995-09-20 | Isis Innovation Limited | Peptide corresponding to cd44 exon 6, antibodies specific for said peptide and use of these antibodies for diagnosis of tumors |
JPH08511419A (en) * | 1993-06-18 | 1996-12-03 | ヤルカネン、シルパ | Composition and diagnostic method using monoclonal antibody against CD44v6 |
EP0767379A1 (en) * | 1993-06-22 | 1997-04-09 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Method for the diagnosis and analysis of colon carcinoma |
-
1995
- 1995-02-06 UA UA97010045A patent/UA58482C2/en unknown
- 1995-06-02 CZ CZ19963591A patent/CZ291274B6/en not_active IP Right Cessation
- 1995-06-02 ES ES95922496T patent/ES2151603T3/en not_active Expired - Lifetime
- 1995-06-02 DE DE59508864T patent/DE59508864D1/en not_active Expired - Lifetime
- 1995-06-02 WO PCT/EP1995/002126 patent/WO1995033771A1/en active IP Right Grant
- 1995-06-02 PL PL317536A patent/PL190897B1/en not_active IP Right Cessation
- 1995-06-02 PT PT95922496T patent/PT765343E/en unknown
- 1995-06-02 SK SK1548-96A patent/SK282649B6/en unknown
- 1995-06-02 AT AT95922496T patent/ATE197592T1/en active
- 1995-06-02 NZ NZ288224A patent/NZ288224A/en unknown
- 1995-06-02 US US08/750,359 patent/US5916561A/en not_active Expired - Lifetime
- 1995-06-02 CA CA002192370A patent/CA2192370A1/en not_active Abandoned
- 1995-06-02 HU HU9603387A patent/HU220168B/en not_active IP Right Cessation
- 1995-06-02 SI SI9530457T patent/SI0765343T1/en unknown
- 1995-06-02 RO RO96-02287A patent/RO118753B1/en unknown
- 1995-06-02 KR KR1019960706939A patent/KR100379217B1/en not_active IP Right Cessation
- 1995-06-02 CN CN95194169A patent/CN1125083C/en not_active Expired - Fee Related
- 1995-06-02 EP EP95922496A patent/EP0765343B1/en not_active Expired - Lifetime
- 1995-06-02 DK DK95922496T patent/DK0765343T3/en active
- 1995-06-02 RU RU97100179/13A patent/RU2204606C2/en not_active IP Right Cessation
- 1995-06-02 JP JP50035496A patent/JP3387929B2/en not_active Expired - Fee Related
- 1995-06-02 BR BR9507964A patent/BR9507964A/en not_active IP Right Cessation
- 1995-06-07 CO CO95024702A patent/CO4410258A1/en unknown
-
1996
- 1996-12-03 BG BG101024A patent/BG64181B1/en unknown
- 1996-12-04 FI FI964845A patent/FI964845A/en not_active IP Right Cessation
- 1996-12-05 KR KR1019967006939A patent/KR970703368A/en unknown
- 1996-12-06 NO NO19965239A patent/NO317948B1/en not_active IP Right Cessation
-
1998
- 1998-12-07 HK HK98112912A patent/HK1011697A1/en not_active IP Right Cessation
-
2001
- 2001-02-07 GR GR20010400215T patent/GR3035388T3/en not_active IP Right Cessation
-
2002
- 2002-06-19 JP JP2002178280A patent/JP2003034700A/en active Pending
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