RU96120197A - APPLICATION OF THIOCETHENE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF HEPATITIS IN - Google Patents
APPLICATION OF THIOCETHENE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF HEPATITIS INInfo
- Publication number
- RU96120197A RU96120197A RU96120197/14A RU96120197A RU96120197A RU 96120197 A RU96120197 A RU 96120197A RU 96120197/14 A RU96120197/14 A RU 96120197/14A RU 96120197 A RU96120197 A RU 96120197A RU 96120197 A RU96120197 A RU 96120197A
- Authority
- RU
- Russia
- Prior art keywords
- ylidene
- acetate
- isopropyl
- carbamoyl
- dithietan
- Prior art date
Links
- 230000002265 prevention Effects 0.000 title claims 2
- 208000006454 Hepatitis Diseases 0.000 title 1
- 231100000283 hepatitis Toxicity 0.000 title 1
- -1 2-thiazolyl Chemical group 0.000 claims 12
- QTBSBXVTEAMEQO-UHFFFAOYSA-M acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000004432 carbon atoms Chemical group C* 0.000 claims 2
- CWMKZYCJCZVSHO-UHFFFAOYSA-N ethenethione Chemical class C=C=S CWMKZYCJCZVSHO-UHFFFAOYSA-N 0.000 claims 2
- 125000004521 1,3,4-thiadiazol-2-yl group Chemical group S1C(=NN=C1)* 0.000 claims 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 208000002672 Hepatitis B Diseases 0.000 claims 1
- YPIQVCUJEKAZCP-UHFFFAOYSA-N Malotilate Chemical compound CC(C)OC(=O)C(C(=O)OC(C)C)=C1SC=CS1 YPIQVCUJEKAZCP-UHFFFAOYSA-N 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
Claims (2)
где Y является -CH2 - или -CH=CH-;
A является NH или O;
R1 является неразветвленной или разветвленной алкильной группой, имеющей 1 - 4 атомов углерода; и
когда A является O, R2 является неразветвленной или разветвленной алкильной группой, имеющей 1 - 4 атомов углерода, и когда A является NH, R2 является бензилом, 2-пиридилом, 2-тиазолилом, 4-метилтиазол-2-илом, 4-карбокситиазол-2-илом или 1,3,4-тиадиазол-2-илом.1. The use of a thioketene derivative of the formula (1) or a pharmaceutically acceptable salt thereof for the prevention or treatment of hepatitis B:
where Y is —CH 2 - or —CH = CH—;
A is NH or O;
R 1 is an unbranched or branched alkyl group having 1 to 4 carbon atoms; and
when A is O, R 2 is a straight or branched alkyl group having 1 to 4 carbon atoms, and when A is NH, R 2 is benzyl, 2-pyridyl, 2-thiazolyl, 4-methylthiazol-2-yl, 4- carboxythiazol-2-yl or 1,3,4-thiadiazol-2-yl.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR95-10214 | 1995-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU96120197A true RU96120197A (en) | 1998-12-27 |
Family
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