RU94038043A - Применение замещенных производных аденина для лечения множественного склероза - Google Patents

Применение замещенных производных аденина для лечения множественного склероза

Info

Publication number
RU94038043A
RU94038043A RU94038043/14A RU94038043A RU94038043A RU 94038043 A RU94038043 A RU 94038043A RU 94038043/14 A RU94038043/14 A RU 94038043/14A RU 94038043 A RU94038043 A RU 94038043A RU 94038043 A RU94038043 A RU 94038043A
Authority
RU
Russia
Prior art keywords
multiple sclerosis
adenine derivatives
treatment
substituted adenine
sclerosis treatment
Prior art date
Application number
RU94038043/14A
Other languages
English (en)
Other versions
RU2130308C1 (ru
Inventor
Беутлер Эрнст
Us]
Original Assignee
Дзе Скриппс Ресеч Инститьют (Us)
Дзе Скриппс Ресеч Инститьют
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Дзе Скриппс Ресеч Инститьют (Us), Дзе Скриппс Ресеч Инститьют filed Critical Дзе Скриппс Ресеч Инститьют (Us)
Publication of RU94038043A publication Critical patent/RU94038043A/ru
Application granted granted Critical
Publication of RU2130308C1 publication Critical patent/RU2130308C1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Изобретение относится к лечению пациентов, страдающих рассеянным склерозом, с помощью терапевтических средств, содержащих производные аденина, такие как 2-хлор-2'-дезоксиаденозин, что значительно улучшает состояние больного.

Claims (1)

  1. Изобретение относится к лечению пациентов, страдающих рассеянным склерозом, с помощью терапевтических средств, содержащих производные аденина, такие как 2-хлор-2'-дезоксиаденозин, что значительно улучшает состояние больного.
RU94038043A 1992-02-19 1993-02-18 Применение замещенных производных аденина для лечения рассеянного склероза RU2130308C1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/838,546 1992-02-19
US07/838,546 US5310732A (en) 1986-02-03 1992-02-19 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis
US07/838.546 1992-02-19
PCT/US1993/001467 WO1993016706A1 (en) 1992-02-19 1993-02-18 Use of substituted adenine derivatives for treating multiple sclerosis

Publications (2)

Publication Number Publication Date
RU94038043A true RU94038043A (ru) 1996-11-20
RU2130308C1 RU2130308C1 (ru) 1999-05-20

Family

ID=25277387

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94038043A RU2130308C1 (ru) 1992-02-19 1993-02-18 Применение замещенных производных аденина для лечения рассеянного склероза

Country Status (15)

Country Link
US (4) US5310732A (ru)
EP (1) EP0626853B1 (ru)
JP (1) JP2688113B2 (ru)
AT (1) ATE192045T1 (ru)
AU (1) AU682818B2 (ru)
BR (1) BR9305907A (ru)
CA (1) CA2130275C (ru)
CH (1) CH684310A5 (ru)
DE (1) DE69328474T2 (ru)
DK (1) DK0626853T3 (ru)
FI (1) FI943805A (ru)
HU (1) HU218656B (ru)
NO (2) NO309025B1 (ru)
RU (1) RU2130308C1 (ru)
WO (1) WO1993016706A1 (ru)

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Also Published As

Publication number Publication date
NO20000762L (no) 1994-09-13
HU9402392D0 (en) 1994-10-28
US5506213A (en) 1996-04-09
WO1993016706A1 (en) 1993-09-02
HU218656B (hu) 2000-10-28
BR9305907A (pt) 1997-10-21
FI943805A (fi) 1994-10-19
US5541164A (en) 1996-07-30
JPH07507540A (ja) 1995-08-24
JP2688113B2 (ja) 1997-12-08
DE69328474T2 (de) 2000-09-28
DE69328474D1 (de) 2000-05-31
EP0626853B1 (en) 2000-04-26
AU3724993A (en) 1993-09-13
HUT68030A (en) 1995-05-29
DK0626853T3 (da) 2000-08-07
FI943805A0 (fi) 1994-08-18
NO309025B1 (no) 2000-12-04
NO942765D0 (no) 1994-07-25
CH684310A5 (de) 1994-08-31
AU682818B2 (en) 1997-10-23
RU2130308C1 (ru) 1999-05-20
CA2130275A1 (en) 1993-09-02
NO20000762D0 (no) 2000-02-16
US5310732A (en) 1994-05-10
EP0626853A1 (en) 1994-12-07
US5506214A (en) 1996-04-09
CA2130275C (en) 1999-06-29
NO322328B1 (no) 2006-09-18
ATE192045T1 (de) 2000-05-15
NO942765L (no) 1994-09-13

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