RU94027680A - Паращитовидный гормон и ралоксифон для увеличения массы кости, фармацевтический состав и способ увеличения костной массы - Google Patents
Паращитовидный гормон и ралоксифон для увеличения массы кости, фармацевтический состав и способ увеличения костной массыInfo
- Publication number
- RU94027680A RU94027680A RU94027680/14A RU94027680A RU94027680A RU 94027680 A RU94027680 A RU 94027680A RU 94027680/14 A RU94027680/14 A RU 94027680/14A RU 94027680 A RU94027680 A RU 94027680A RU 94027680 A RU94027680 A RU 94027680A
- Authority
- RU
- Russia
- Prior art keywords
- mass increase
- parathyroid hormone
- raloxifen
- pharmaceutical composition
- osseous
- Prior art date
Links
- 102000003982 Parathyroid hormone Human genes 0.000 title claims abstract 8
- 108090000445 Parathyroid hormone Proteins 0.000 title claims abstract 8
- 239000000199 parathyroid hormone Substances 0.000 title claims abstract 8
- 229960001319 parathyroid hormone Drugs 0.000 title claims abstract 8
- 238000000034 method Methods 0.000 title claims abstract 5
- 210000000988 bone and bone Anatomy 0.000 title claims 3
- AUYLVPGDOVEOML-UHFFFAOYSA-N [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(piperidin-1-ylmethoxy)phenyl]methanone Chemical compound C1=CC(O)=CC=C1C1=C(C(=O)C=2C=CC(OCN3CCCCC3)=CC=2)C2=CC=C(O)C=C2S1 AUYLVPGDOVEOML-UHFFFAOYSA-N 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000020084 Bone disease Diseases 0.000 claims abstract 4
- GZUITABIAKMVPG-UHFFFAOYSA-N raloxifene Chemical compound C1=CC(O)=CC=C1C1=C(C(=O)C=2C=CC(OCCN3CCCCC3)=CC=2)C2=CC=C(O)C=C2S1 GZUITABIAKMVPG-UHFFFAOYSA-N 0.000 claims 4
- 229960004622 raloxifene Drugs 0.000 claims 4
- 230000000694 effects Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Изобретение включает в себя способ увеличения костной массы у пациента путем ввода паращитовидного гормона и ралоксифена. Другим признаком изобретения является способ лечения заболевания кости путем ввода паращитовидного гормона и ралоксифена. Также изобретение относится к составу из паращитовидного гормона и ралоксифена для увеличения костной массы у пациента. Другим признаком изобретения является композиция из паращитовидного гормона и ралоксифена для печения заболевания кости у пациента.
Claims (1)
- Изобретение включает в себя способ увеличения костной массы у пациента путем ввода паращитовидного гормона и ралоксифена. Другим признаком изобретения является способ лечения заболевания кости путем ввода паращитовидного гормона и ралоксифена. Также изобретение относится к составу из паращитовидного гормона и ралоксифена для увеличения костной массы у пациента. Другим признаком изобретения является композиция из паращитовидного гормона и ралоксифена для печения заболевания кости у пациента.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9648093A | 1993-07-22 | 1993-07-22 | |
US08/096,480 | 1993-07-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU94027680A true RU94027680A (ru) | 1996-11-10 |
RU2155042C2 RU2155042C2 (ru) | 2000-08-27 |
Family
ID=22257534
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU94027680/14A RU2155042C2 (ru) | 1993-07-22 | 1994-07-19 | Паращитовидный гормон и ралоксифен для увеличения массы кости, фармацевтический состав и способ увеличения костной массы |
Country Status (30)
Country | Link |
---|---|
US (1) | US5510370A (ru) |
EP (1) | EP0635270B1 (ru) |
JP (1) | JPH0769920A (ru) |
KR (1) | KR100306852B1 (ru) |
CN (1) | CN1105577C (ru) |
AT (1) | ATE189959T1 (ru) |
AU (1) | AU686628B2 (ru) |
BR (1) | BR9402902A (ru) |
CA (1) | CA2128376A1 (ru) |
CY (1) | CY2192B1 (ru) |
CZ (1) | CZ289648B6 (ru) |
DE (1) | DE69423146T2 (ru) |
DK (1) | DK0635270T3 (ru) |
ES (1) | ES2142380T3 (ru) |
GR (1) | GR3033492T3 (ru) |
HK (1) | HK1013800A1 (ru) |
HU (1) | HU219382B (ru) |
IL (1) | IL110350A (ru) |
MY (1) | MY124311A (ru) |
NO (1) | NO942708L (ru) |
NZ (2) | NZ264027A (ru) |
PE (1) | PE14595A1 (ru) |
PH (1) | PH30686A (ru) |
PL (1) | PL304348A1 (ru) |
PT (1) | PT635270E (ru) |
RU (1) | RU2155042C2 (ru) |
SI (1) | SI0635270T1 (ru) |
TW (1) | TW303299B (ru) |
YU (1) | YU49170B (ru) |
ZA (1) | ZA945249B (ru) |
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US5770609A (en) | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6395494B1 (en) | 1993-05-13 | 2002-05-28 | Neorx Corporation | Method to determine TGF-β |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
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US5554601A (en) * | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
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US20040186185A1 (en) * | 1998-05-07 | 2004-09-23 | Steiner Mitchell S. | Method for treatment and chemoprevention of prostate cancer |
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US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
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-
1993
- 1993-08-02 TW TW082106163A patent/TW303299B/zh active
-
1994
- 1994-07-18 AT AT94305238T patent/ATE189959T1/de not_active IP Right Cessation
- 1994-07-18 PT PT94305238T patent/PT635270E/pt unknown
- 1994-07-18 IL IL11035094A patent/IL110350A/en not_active IP Right Cessation
- 1994-07-18 ES ES94305238T patent/ES2142380T3/es not_active Expired - Lifetime
- 1994-07-18 DK DK94305238T patent/DK0635270T3/da active
- 1994-07-18 SI SI9430323T patent/SI0635270T1/xx unknown
- 1994-07-18 DE DE69423146T patent/DE69423146T2/de not_active Expired - Fee Related
- 1994-07-18 NZ NZ264027A patent/NZ264027A/en unknown
- 1994-07-18 NZ NZ280040A patent/NZ280040A/en unknown
- 1994-07-18 ZA ZA945249A patent/ZA945249B/xx unknown
- 1994-07-18 PE PE1994246921A patent/PE14595A1/es not_active Application Discontinuation
- 1994-07-18 EP EP94305238A patent/EP0635270B1/en not_active Expired - Lifetime
- 1994-07-18 CZ CZ19941733A patent/CZ289648B6/cs not_active IP Right Cessation
- 1994-07-19 AU AU67577/94A patent/AU686628B2/en not_active Ceased
- 1994-07-19 JP JP6166809A patent/JPH0769920A/ja active Pending
- 1994-07-19 PL PL94304348A patent/PL304348A1/xx unknown
- 1994-07-19 NO NO942708A patent/NO942708L/no not_active Application Discontinuation
- 1994-07-19 RU RU94027680/14A patent/RU2155042C2/ru not_active IP Right Cessation
- 1994-07-19 CA CA002128376A patent/CA2128376A1/en not_active Abandoned
- 1994-07-20 KR KR1019940017456A patent/KR100306852B1/ko not_active IP Right Cessation
- 1994-07-20 PH PH48671A patent/PH30686A/en unknown
- 1994-07-21 CN CN94108159A patent/CN1105577C/zh not_active Expired - Fee Related
- 1994-07-21 BR BR9402902A patent/BR9402902A/pt not_active Application Discontinuation
- 1994-07-21 YU YU46794A patent/YU49170B/sh unknown
- 1994-07-21 HU HU9402157A patent/HU219382B/hu not_active IP Right Cessation
- 1994-07-22 MY MYPI94001920A patent/MY124311A/en unknown
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1995
- 1995-03-06 US US08/400,436 patent/US5510370A/en not_active Expired - Fee Related
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1998
- 1998-12-23 HK HK98115198A patent/HK1013800A1/xx not_active IP Right Cessation
-
2000
- 2000-05-24 GR GR20000401189T patent/GR3033492T3/el not_active IP Right Cessation
- 2000-08-02 CY CY0000034A patent/CY2192B1/xx unknown
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