RU93058614A - Мутант вируса герпеса, композиции, диагностические наборы, способы определения инфекции - Google Patents
Мутант вируса герпеса, композиции, диагностические наборы, способы определения инфекцииInfo
- Publication number
- RU93058614A RU93058614A RU93058614/13A RU93058614A RU93058614A RU 93058614 A RU93058614 A RU 93058614A RU 93058614/13 A RU93058614/13 A RU 93058614/13A RU 93058614 A RU93058614 A RU 93058614A RU 93058614 A RU93058614 A RU 93058614A
- Authority
- RU
- Russia
- Prior art keywords
- bhv
- mutant
- herpes virus
- diagnostic kits
- compositions
- Prior art date
Links
- 241001529453 unidentified herpesvirus Species 0.000 title claims 3
- 238000009007 Diagnostic Kit Methods 0.000 title claims 2
- 201000009910 diseases by infectious agent Diseases 0.000 title claims 2
- 239000000203 mixture Substances 0.000 title 1
- 241001465754 Metazoa Species 0.000 claims 2
- 229960005486 vaccines Drugs 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 102000003886 Glycoproteins Human genes 0.000 claims 1
- 108090000288 Glycoproteins Proteins 0.000 claims 1
- 102000004965 antibodies Human genes 0.000 claims 1
- 108090001123 antibodies Proteins 0.000 claims 1
- 230000002238 attenuated Effects 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 230000001717 pathogenic Effects 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 238000002255 vaccination Methods 0.000 claims 1
Claims (1)
- Изобретение относится к области вакцинации и диагностики в отношении заболеваний, вызываемых патогенными бактериями, в частности к живым ослабленным и инактивированным вакцинам для защиты животных против вируса герпеса типа I. Вакцина создана на основе мутанта вируса герпеса BHV-1, имеющего делецию в дЕ-гене гликопротеида, с геном, имеющим соответствующее местоположение в геноме BHV-1, причем указанная делеция позволяет мутанту отличаться серологически от BHV-1 дикого типа. Изобретение касается также диагностических наборов для обнаружения нуклеиновой кислоты BHV-1, антител, специфичных для BHV-1, белка BHV-1 и способа определения инфекции BHV-1 у животных. Разработанные препараты и способ отличаются высокой эффективностью и безопасностью.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL9100989A NL9100989A (nl) | 1991-06-07 | 1991-06-07 | Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1. |
NL9100989 | 1991-06-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU93058614A true RU93058614A (ru) | 1997-02-10 |
RU2170254C2 RU2170254C2 (ru) | 2001-07-10 |
Family
ID=19859344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU93058614/13A RU2170254C2 (ru) | 1991-06-07 | 1992-06-05 | Штамм коровьего вируса герпеса типа 1 (внv-1) сncm №1-1213, вакцина, диагностический серологический реактив, способ вакцинации, способ серологического отличия |
Country Status (20)
Country | Link |
---|---|
US (3) | US5676951A (ru) |
EP (1) | EP0587805B2 (ru) |
JP (3) | JPH06508032A (ru) |
KR (1) | KR100293761B1 (ru) |
AT (1) | ATE143412T1 (ru) |
AU (1) | AU671802B2 (ru) |
CA (1) | CA2110519C (ru) |
CZ (1) | CZ283283B6 (ru) |
DE (1) | DE69214146T3 (ru) |
DK (1) | DK0587805T4 (ru) |
ES (1) | ES2097340T5 (ru) |
FI (1) | FI110060B (ru) |
GR (1) | GR3022138T3 (ru) |
HU (1) | HU219602B (ru) |
NL (1) | NL9100989A (ru) |
NO (2) | NO934431L (ru) |
RU (1) | RU2170254C2 (ru) |
SK (1) | SK280862B6 (ru) |
UA (1) | UA40571C2 (ru) |
WO (1) | WO1992021751A1 (ru) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5783195A (en) * | 1991-07-18 | 1998-07-21 | Syntro Corporation | Recombinant infectious bovine rhinotracheitis virus S-IBR-052 and uses thereof |
US6410033B1 (en) | 1987-07-27 | 2002-06-25 | Syntro Corporation | Recombinant infectious bovine rhinotracheitis virus |
FR2693472B1 (fr) * | 1992-06-26 | 1994-12-23 | Rhone Merieux | Mutants du virus de la rhinotrachéite infectieuse bovine, délétés dans l'un des gènes des glycoprotéines mineures, vaccins préparés à partir de ces souches, méthodes de production et méthodes d'utilisation. |
DE69132404T2 (de) * | 1990-10-04 | 2001-02-15 | Research Corp. Technologies, Inc. | Varicella-zoster virusantigen |
NL9100989A (nl) * | 1991-06-07 | 1993-01-04 | Stichting Centr Diergeneeskund | Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1. |
CA2113641A1 (en) * | 1991-07-18 | 1993-02-04 | Mark D. Cochran | Recombinant infectious bovine rhinotracheitis virus |
DE4141400A1 (de) * | 1991-12-16 | 1993-06-17 | Bayer Ag | Impfstoffe auf basis geaenderter boviner herpesviren typ 1 |
DE69333333T2 (de) * | 1992-03-20 | 2004-09-23 | Max Planck Gesellschaft zur Förderung der Wissenschaften e.V. | Auf fungus reagierendes chimaeres gen |
WO1994024296A2 (en) * | 1993-04-19 | 1994-10-27 | University Of Saskatchewan | Recombinant bovine herpesvirus type 1 vaccines |
CA2136381A1 (en) * | 1993-11-23 | 1995-05-24 | Gunther Keil | Vector vaccines of bovine herpesvirus 1 |
ES2074965B1 (es) * | 1994-01-31 | 1996-05-01 | Hipra Lab Sa | Virus mutante recombinante de rinotraqueitis infecciosa bovina y vacunas que lo contienen. |
ES2088371B1 (es) * | 1995-02-01 | 1997-04-16 | Hipra Lab Sa | Procedimiento para la produccion en forma recombinante de antigenos de la glicoproteina ge de herpesvirus bovino tipo 1 y su uso en la diferenciacion serologica entre animales infectados y animales vacunados. |
US6221360B1 (en) * | 1996-02-26 | 2001-04-24 | Kansas State University Research Foundation | Infectious bovine rhinotracheitis vaccines and methods |
US6284251B1 (en) * | 1996-02-26 | 2001-09-04 | Kansas State University Research Foundation | BHV-1 gene-deleted virus vaccine |
EP2365082A1 (en) | 2000-06-27 | 2011-09-14 | Pfizer Animal Health S.A. | BVDV virus-like particles |
US6935866B2 (en) * | 2002-04-02 | 2005-08-30 | Adc Telecommunications, Inc. | Card edge coaxial connector |
EP1594537B1 (en) | 2003-02-19 | 2012-10-24 | Merial | Vaccination or immunization using a prime-boost regimen against brsv, bhv-1, bvdv, bpi-3 |
CA2693137C (en) * | 2007-07-19 | 2014-04-08 | Azad Kumar Kaushik | Engineered scfv against bovine herpes virus type i |
EP2108375A1 (de) * | 2008-04-10 | 2009-10-14 | Riemser Arzneimittel AG | Lebendimpfstoffzusammensetzung |
CN102649948B (zh) * | 2011-02-23 | 2016-05-25 | 华中农业大学 | 牛传染性鼻气管炎ΔTK/ΔgE基因缺失标志活疫苗及制备方法 |
US8877211B2 (en) | 2011-06-27 | 2014-11-04 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Bovine herpes virus vaccine with multiple mutations |
CA2839941C (en) * | 2011-07-05 | 2019-12-31 | The State Of Queensland Acting Through The Department Of Agriculture, Fisheries And Forestry | Recombinant low virulence bovine herpesvirus 1 (bohv-1) vaccine vectors |
CN103923884B (zh) * | 2014-02-21 | 2017-03-29 | 普莱柯生物工程股份有限公司 | 一种猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用 |
DE202015009507U1 (de) | 2014-05-08 | 2018-01-11 | In3Diagnostic S.R.L. | Kit und in-vitro-Methode zur Identifizierung Bovine Herpes Virus 1-Infektionen |
EP3779445A1 (en) | 2014-08-01 | 2021-02-17 | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College | Bovine herpesvirus detection and treatment |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4703011A (en) * | 1985-11-12 | 1987-10-27 | Novagene, Inc. | Thymidine kinase deletion mutants of bovine herpesvirus-1 |
US5593873A (en) * | 1986-01-27 | 1997-01-14 | Syntro Corporation | Recombinant infectious bovine rhinotracheitis virus |
US4992051A (en) * | 1987-11-03 | 1991-02-12 | Novagene, Inc. | Infectious bovine rhinotracheitis virus mutants, methods for the production of same and methods for the use of same |
AU2888089A (en) * | 1988-01-26 | 1989-07-27 | Baylor College Of Medicine | Infectious bovine rhinotracheitis virus insertion mutants, vaccines containing same, and methods for the production and use of same |
AU3579089A (en) * | 1988-05-03 | 1989-11-29 | Upjohn Company, The | Glycoprotein h of herpes viruses |
NL9100989A (nl) * | 1991-06-07 | 1993-01-04 | Stichting Centr Diergeneeskund | Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1. |
DE4141400A1 (de) * | 1991-12-16 | 1993-06-17 | Bayer Ag | Impfstoffe auf basis geaenderter boviner herpesviren typ 1 |
-
1991
- 1991-06-07 NL NL9100989A patent/NL9100989A/nl not_active Application Discontinuation
-
1992
- 1992-06-05 UA UA93004426A patent/UA40571C2/ru unknown
- 1992-06-05 CA CA002110519A patent/CA2110519C/en not_active Expired - Lifetime
- 1992-06-05 AT AT92914642T patent/ATE143412T1/de active
- 1992-06-05 WO PCT/NL1992/000097 patent/WO1992021751A1/en active IP Right Grant
- 1992-06-05 SK SK1375-93A patent/SK280862B6/sk not_active IP Right Cessation
- 1992-06-05 RU RU93058614/13A patent/RU2170254C2/ru active
- 1992-06-05 EP EP92914642A patent/EP0587805B2/en not_active Expired - Lifetime
- 1992-06-05 KR KR1019930703773A patent/KR100293761B1/ko not_active IP Right Cessation
- 1992-06-05 DK DK92914642T patent/DK0587805T4/da active
- 1992-06-05 DE DE69214146T patent/DE69214146T3/de not_active Expired - Lifetime
- 1992-06-05 JP JP5500368A patent/JPH06508032A/ja active Pending
- 1992-06-05 AU AU22750/92A patent/AU671802B2/en not_active Expired
- 1992-06-05 HU HU9303470A patent/HU219602B/hu unknown
- 1992-06-05 ES ES92914642T patent/ES2097340T5/es not_active Expired - Lifetime
- 1992-06-05 US US08/150,203 patent/US5676951A/en not_active Expired - Lifetime
- 1992-06-05 CZ CS932646A patent/CZ283283B6/cs not_active IP Right Cessation
-
1993
- 1993-12-06 NO NO934431A patent/NO934431L/no unknown
- 1993-12-06 NO NO934431D patent/NO934431D0/no unknown
- 1993-12-07 FI FI935459A patent/FI110060B/fi not_active IP Right Cessation
-
1995
- 1995-05-31 US US08/454,730 patent/US5789177A/en not_active Expired - Lifetime
-
1996
- 1996-12-23 GR GR960403580T patent/GR3022138T3/el unknown
-
1997
- 1997-10-14 US US08/949,788 patent/US6403097B1/en not_active Expired - Lifetime
-
2006
- 2006-04-11 JP JP2006109215A patent/JP4486055B2/ja not_active Expired - Lifetime
-
2009
- 2009-11-26 JP JP2009268316A patent/JP2010104367A/ja active Pending
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