RU93004806A - ARYLACETAMIDES, METHOD FOR THEIR PRODUCTION AND APPLICATION, PHARMACEUTICAL COMPOSITION - Google Patents

ARYLACETAMIDES, METHOD FOR THEIR PRODUCTION AND APPLICATION, PHARMACEUTICAL COMPOSITION

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Publication number
RU93004806A
RU93004806A RU93004806/04A RU93004806A RU93004806A RU 93004806 A RU93004806 A RU 93004806A RU 93004806/04 A RU93004806/04 A RU 93004806/04A RU 93004806 A RU93004806 A RU 93004806A RU 93004806 A RU93004806 A RU 93004806A
Authority
RU
Russia
Prior art keywords
arylacetamides
production
application
pharmaceutical composition
arylacetamide
Prior art date
Application number
RU93004806/04A
Other languages
Russian (ru)
Other versions
RU2125041C1 (en
Inventor
Готтшлих Рудольф
Аккерманн Карл-Аугуст
Прюхер Хельмут
Зейфрид Христоф
Грайнер Хартмут
Бартошик Герд
Маулер Франк
Шторер Манфред
Барбер Эндрю
Original Assignee
Мерк Патент Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4215213A external-priority patent/DE4215213A1/en
Application filed by Мерк Патент Гмбх filed Critical Мерк Патент Гмбх
Publication of RU93004806A publication Critical patent/RU93004806A/en
Application granted granted Critical
Publication of RU2125041C1 publication Critical patent/RU2125041C1/en

Links

Claims (1)

Новые арилацетамиды формулы:
Figure 00000001

где Q, R1, R2 и R3 имеют указанное в п.1 формулы изобретения значение, обладают анальгетическими и нейрозащитными свойствами и с высоким сродством связывают каппа-рецепторы.New arylacetamide formula:
Figure 00000001

where Q, R 1 , R 2 and R 3 have the meaning specified in claim 1, have analgesic and neuroprotective properties and bind to kappa receptors with high affinity.
RU93004806/04A 1992-05-09 1993-05-06 Arylacetamides, method of preparing same, pharmaceutical composition and method of preparing thereof RU2125041C1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4215213A DE4215213A1 (en) 1992-05-09 1992-05-09 Arylacetamide
DEP4215213.5 1992-05-09

Publications (2)

Publication Number Publication Date
RU93004806A true RU93004806A (en) 1996-04-27
RU2125041C1 RU2125041C1 (en) 1999-01-20

Family

ID=6458428

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93004806/04A RU2125041C1 (en) 1992-05-09 1993-05-06 Arylacetamides, method of preparing same, pharmaceutical composition and method of preparing thereof

Country Status (22)

Country Link
US (1) US5532266A (en)
EP (1) EP0569802B1 (en)
JP (1) JP3210771B2 (en)
KR (1) KR100241637B1 (en)
CN (1) CN1041087C (en)
AT (1) ATE168368T1 (en)
AU (1) AU662051B2 (en)
BR (1) BR1100581A (en)
CA (1) CA2095797C (en)
CZ (1) CZ289961B6 (en)
DE (2) DE4215213A1 (en)
DK (1) DK0569802T3 (en)
ES (1) ES2121030T3 (en)
HK (1) HK1011990A1 (en)
HU (1) HU214578B (en)
NO (1) NO179789C (en)
PL (1) PL173779B1 (en)
RU (1) RU2125041C1 (en)
SK (1) SK282646B6 (en)
TW (1) TW372961B (en)
UA (1) UA32543C2 (en)
ZA (1) ZA933222B (en)

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BR0309969A (en) 2002-05-17 2005-04-26 Merck Patent Gmbh Use of compounds that are effective as selective opioid receptor modulators
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US6852713B2 (en) * 2003-04-16 2005-02-08 Adolor Corporation Lactam derivatives and methods of their use
US6992193B2 (en) 2003-06-10 2006-01-31 Adolor Corporation Sulfonylamino phenylacetamide derivatives and methods of their use
US7034051B2 (en) * 2003-08-28 2006-04-25 Adolor Corporation Fused bicyclic carboxamide derivatives and methods of their use
WO2005046687A1 (en) * 2003-10-30 2005-05-26 Tioga Pharmaceuticals, Inc. Use of selective opiate receptor modulators in the treatment of neuropathy
US7160902B2 (en) * 2003-11-14 2007-01-09 Adolor Corporation Amide derivatives and methods of their use
JP2007528898A (en) * 2004-03-12 2007-10-18 イーライ リリー アンド カンパニー Opioid receptor antagonist
CN101677997B (en) 2007-03-30 2012-05-09 泰奥加制药公司 Kappa-opiate agonists for the treatment of diarrhea-predominant and alternating irritable bowel syndrome
JP5776554B2 (en) * 2009-11-18 2015-09-09 日本ゼオン株式会社 Fluorene compound, synthetic polymer stabilizer containing the fluorene compound, and composition containing the fluorene compound
CN103664727A (en) * 2013-12-19 2014-03-26 无锡万全医药技术有限公司 Technology for preparing 1-[(3s)-3-hydroxypyrrolidine-1-base]-(2s)-2-methylamino-2-phenylethane with one-pot method
CN103772257A (en) * 2013-12-31 2014-05-07 无锡万全医药技术有限公司 Method for preparing 2-((3s)-3-hydroxy pyrrolidine-1-yl)-(1s)-1-phenethyl carbamate
AU2017311691B2 (en) 2016-08-18 2021-12-02 Vidac Pharma Ltd. Piperazine derivatives, pharmaceutical compositions and methods of use thereof
EP3558300B1 (en) 2016-12-21 2021-11-24 Tioga Pharmaceuticals, Inc. Solid pharmaceutical formulations of asimadoline
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