RU93004697A - DERIVATIVES OF INDOBENZOLHINOLINA - Google Patents
DERIVATIVES OF INDOBENZOLHINOLINAInfo
- Publication number
- RU93004697A RU93004697A RU93004697/04A RU93004697A RU93004697A RU 93004697 A RU93004697 A RU 93004697A RU 93004697/04 A RU93004697/04 A RU 93004697/04A RU 93004697 A RU93004697 A RU 93004697A RU 93004697 A RU93004697 A RU 93004697A
- Authority
- RU
- Russia
- Prior art keywords
- hydrogen
- indobenzolhinolina
- derivatives
- alkyl
- hydroxyalkyl
- Prior art date
Links
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 230000003288 anthiarrhythmic Effects 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 230000000707 stereoselective Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 230000002194 synthesizing Effects 0.000 claims 1
Claims (1)
где R1 является водородом или алкилом; Xв и Yв являются водородом или гидроксилом; Z является -NRaRb, где Ra и Rb являются водородом, алкилом или гидроксиалкилом, или циклической аминогруппой; и их фармацевтически приемлемые соли, которые обладают повышенной противоаритмической активностью и могут быть получены стереоспецифическим синтезом.Optically active compounds of the formula are described:
where R 1 is hydrogen or alkyl; X in and Y in are hydrogen or hydroxyl; Z is —NR a R b , where R a and R b are hydrogen, alkyl or hydroxyalkyl, or a cyclic amino group; and their pharmaceutically acceptable salts, which have increased antiarrhythmic activity and can be obtained by stereospecific synthesis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU93004697A RU2051916C1 (en) | 1993-04-02 | 1993-04-02 | Optically active derivatives of indolebenzoquinoline or their pharmaceutically acceptable salts |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1-223959 | 1989-08-30 | ||
| RU93004697A RU2051916C1 (en) | 1993-04-02 | 1993-04-02 | Optically active derivatives of indolebenzoquinoline or their pharmaceutically acceptable salts |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU4831108 Division |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2051916C1 RU2051916C1 (en) | 1996-01-10 |
| RU93004697A true RU93004697A (en) | 1996-03-20 |
Family
ID=20136395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU93004697A RU2051916C1 (en) | 1993-04-02 | 1993-04-02 | Optically active derivatives of indolebenzoquinoline or their pharmaceutically acceptable salts |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2051916C1 (en) |
-
1993
- 1993-04-02 RU RU93004697A patent/RU2051916C1/en active
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