RU92015867A - CHITOZAN LOW-MOLECULAR WATER-SOLUBLE AND METHOD FOR ITS PRODUCTION - Google Patents

CHITOZAN LOW-MOLECULAR WATER-SOLUBLE AND METHOD FOR ITS PRODUCTION

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Publication number
RU92015867A
RU92015867A RU92015867/04A RU92015867A RU92015867A RU 92015867 A RU92015867 A RU 92015867A RU 92015867/04 A RU92015867/04 A RU 92015867/04A RU 92015867 A RU92015867 A RU 92015867A RU 92015867 A RU92015867 A RU 92015867A
Authority
RU
Russia
Prior art keywords
soluble
chitosan
chitozan
production
low
Prior art date
Application number
RU92015867/04A
Other languages
Russian (ru)
Other versions
RU2073016C1 (en
Inventor
В.П. Варламов
И.А. Стояченко
М.В. Буданов
Original Assignee
Центр "Биоинженерия" Ран
Filing date
Publication date
Application filed by Центр "Биоинженерия" Ран filed Critical Центр "Биоинженерия" Ран
Priority to RU92015867A priority Critical patent/RU2073016C1/en
Priority claimed from RU92015867A external-priority patent/RU2073016C1/en
Publication of RU92015867A publication Critical patent/RU92015867A/en
Application granted granted Critical
Publication of RU2073016C1 publication Critical patent/RU2073016C1/en

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Claims (1)

Изобретение относится к олигосахаридным соединениям, конкретно к олигомерам хитозана (олигомерам Д-глюкозамина). Хитозан низкомолекулярный водорастворимый может быть использован в качестве иммуномодулятора и антихолесторолика. Он также является потенциальным протовирусным и противоопухолевым препаратом. Задачей настоящего изобретения явлется получение хитозана низкомолекулярного водорастворимого. Для этого 1%-ный раствор хитозана подвергают ферментативному расщеплению иммобилизованным на силикагеле хитиназным комплексом стрептомицетов. Процесс ведут при ph 4,5-5,0 и 45-50oC в течение 16 ч, а затем при 6,0-6,5 при 37oC в течение 8-12 ч.The invention relates to oligosaccharide compounds, specifically to chitosan oligomers (D-glucosamine oligomers). Chitosan low molecular weight water-soluble can be used as an immunomodulator and anticholesterol. It is also a potential protoviral and antitumor drug. An object of the present invention is to provide low molecular weight water soluble chitosan. For this, a 1% solution of chitosan is subjected to enzymatic digestion with a chitinase complex of streptomycetes immobilized on silica gel. The process is carried out at ph 4.5-5.0 and 45-50 o C for 16 hours, and then at 6.0-6.5 at 37 o C for 8-12 hours
RU92015867A 1992-12-31 1992-12-31 Method of low-molecular water-soluble chitosan preparing RU2073016C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU92015867A RU2073016C1 (en) 1992-12-31 1992-12-31 Method of low-molecular water-soluble chitosan preparing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU92015867A RU2073016C1 (en) 1992-12-31 1992-12-31 Method of low-molecular water-soluble chitosan preparing

Publications (2)

Publication Number Publication Date
RU92015867A true RU92015867A (en) 1996-09-10
RU2073016C1 RU2073016C1 (en) 1997-02-10

Family

ID=20135007

Family Applications (1)

Application Number Title Priority Date Filing Date
RU92015867A RU2073016C1 (en) 1992-12-31 1992-12-31 Method of low-molecular water-soluble chitosan preparing

Country Status (1)

Country Link
RU (1) RU2073016C1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5980166A1 (en) * 2008-09-02 2008-11-28 Nova Praxis Ltda CONJUGATE OF A QUITIN DERIVATIVE WITH NATURAL SWEETENERS FOR THE CONTROL OF FATS INGESTED IN HUMANS AND WITH SWEETENING PROPERTIES
RU2627870C1 (en) * 2016-08-12 2017-08-14 Федеральное государственное учреждение "Федеральный исследовательский центр "Фундаментальные основы биотехнологии" Российской академии наук" (ФИЦ Биотехнологии РАН) Method for producing low-molecular chitosan and chitosan oligomers
US20200101103A1 (en) * 2017-04-07 2020-04-02 Cirqle Biomedical Contraception Ivs Reinforcement of mucus barrier properties

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