RU2211221C2 - Способ получения соединения авермектина - Google Patents

Способ получения соединения авермектина Download PDF

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Publication number
RU2211221C2
RU2211221C2 RU2000101832/04A RU2000101832A RU2211221C2 RU 2211221 C2 RU2211221 C2 RU 2211221C2 RU 2000101832/04 A RU2000101832/04 A RU 2000101832/04A RU 2000101832 A RU2000101832 A RU 2000101832A RU 2211221 C2 RU2211221 C2 RU 2211221C2
Authority
RU
Russia
Prior art keywords
compound
alkyl
palladium
carried out
agent
Prior art date
Application number
RU2000101832/04A
Other languages
English (en)
Russian (ru)
Other versions
RU2000101832A (ru
Inventor
Масанори ХОНДА
Хироси КАДОИ
Хиромаса МОРИТА
Исао НАГАКУРА
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of RU2000101832A publication Critical patent/RU2000101832A/ru
Application granted granted Critical
Publication of RU2211221C2 publication Critical patent/RU2211221C2/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2000101832/04A 1997-07-23 1998-06-25 Способ получения соединения авермектина RU2211221C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9700916 1997-07-23
WOPCT/IB97/00916 1997-07-23

Publications (2)

Publication Number Publication Date
RU2000101832A RU2000101832A (ru) 2001-10-27
RU2211221C2 true RU2211221C2 (ru) 2003-08-27

Family

ID=11004591

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2000101832/04A RU2211221C2 (ru) 1997-07-23 1998-06-25 Способ получения соединения авермектина

Country Status (22)

Country Link
EP (1) EP1001962B8 (id)
JP (1) JP3267634B2 (id)
KR (1) KR100339191B1 (id)
CN (1) CN1184227C (id)
AR (1) AR016522A1 (id)
AT (1) ATE227733T1 (id)
AU (1) AU725506B2 (id)
CA (1) CA2294928C (id)
CZ (1) CZ296326B6 (id)
DE (1) DE69809433T2 (id)
DK (1) DK1001962T3 (id)
ES (1) ES2182317T3 (id)
HK (1) HK1027110A1 (id)
HU (1) HUP0004631A3 (id)
ID (1) ID24327A (id)
IL (1) IL133558A0 (id)
PL (1) PL188159B1 (id)
PT (1) PT1001962E (id)
RU (1) RU2211221C2 (id)
TR (1) TR200000196T2 (id)
WO (1) WO1999005156A1 (id)
YU (1) YU71699A (id)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009126310A2 (en) 2008-04-10 2009-10-15 Massachusetts Institute Of Technology Methods for identification and use of agents targeting cancer stem cells
WO2014074805A1 (en) 2012-11-08 2014-05-15 Whitehead Institute For Biomedical Research Selective targeting of cancer stem cells
WO2015168255A1 (en) 2014-04-29 2015-11-05 Whitehead Institute For Biomedical Research Methods and compositions for targeting cancer stem cells
CN104430397B (zh) * 2014-11-06 2016-08-24 山东永泰化工有限公司 一种用于防治红蜘蛛的水分散粒剂
CN107118247B (zh) * 2017-06-14 2019-07-26 博瑞生物医药（苏州）股份有限公司 塞拉菌素的制备方法
CN107021990B (zh) * 2017-06-14 2019-07-12 博瑞生物医药（苏州）股份有限公司 高纯度塞拉菌素的制备方法
CN107188915B (zh) * 2017-07-19 2019-08-02 苏州正永生物医药有限公司 一种塞拉菌素中间体的制备方法
CN107723325B (zh) * 2017-11-28 2021-03-30 山东齐发药业有限公司 基于pH控制的多拉菌素发酵生产方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9402916D0 (en) * 1994-02-16 1994-04-06 Pfizer Ltd Antiparasitic agents
EP0676236A1 (en) * 1994-04-05 1995-10-11 Pfizer Inc. Process for removal of allyl group or allyloxycarbonyl group

Also Published As

Publication number Publication date
CZ200097A3 (cs) 2000-05-17
KR20010014066A (ko) 2001-02-26
JP2000513385A (ja) 2000-10-10
EP1001962B1 (en) 2002-11-13
CA2294928C (en) 2003-01-14
PL338354A1 (en) 2000-10-23
TR200000196T2 (tr) 2000-07-21
EP1001962B8 (en) 2003-03-05
ATE227733T1 (de) 2002-11-15
CN1184227C (zh) 2005-01-12
HUP0004631A2 (hu) 2001-05-28
DK1001962T3 (da) 2002-12-16
HUP0004631A3 (en) 2002-11-28
AU7671498A (en) 1999-02-16
DE69809433T2 (de) 2003-05-08
JP3267634B2 (ja) 2002-03-18
AR016522A1 (es) 2001-07-25
WO1999005156A1 (en) 1999-02-04
HK1027110A1 (en) 2001-01-05
ES2182317T3 (es) 2003-03-01
CZ296326B6 (cs) 2006-02-15
IL133558A0 (en) 2001-04-30
KR100339191B1 (ko) 2002-06-01
ID24327A (id) 2000-07-13
PT1001962E (pt) 2003-01-31
CN1265113A (zh) 2000-08-30
PL188159B1 (pl) 2004-12-31
CA2294928A1 (en) 1999-02-04
AU725506B2 (en) 2000-10-12
YU71699A (sh) 2002-06-19
EP1001962A1 (en) 2000-05-24
DE69809433D1 (de) 2002-12-19

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Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20070626