RU2011107831A - 2-Alkyl-4,6-dimethyl-5-hydroxypyrimidines with antitumor and immunomodulatory effects - Google Patents

2-Alkyl-4,6-dimethyl-5-hydroxypyrimidines with antitumor and immunomodulatory effects Download PDF

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RU2011107831A
RU2011107831A RU2011107831/04A RU2011107831A RU2011107831A RU 2011107831 A RU2011107831 A RU 2011107831A RU 2011107831/04 A RU2011107831/04 A RU 2011107831/04A RU 2011107831 A RU2011107831 A RU 2011107831A RU 2011107831 A RU2011107831 A RU 2011107831A
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dimethyl
hydroxypyrimidines
antitumor
alkyl
immunomodulatory effects
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RU2011107831/04A
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Russian (ru)
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RU2518889C2 (en
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Сергей Борисович Середенин (RU)
Сергей Борисович Середенин
Сергей Васильевич Никитин (RU)
Сергей Васильевич Никитин
Лариса Петровна Коваленко (RU)
Лариса Петровна Коваленко
Андрей Дмитриевич Дурнев (RU)
Андрей Дмитриевич Дурнев
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Учреждение Российской академии медицинских наук Научно-исследовательский институт фармакологии имени В.В. Закусова РАМН (RU)
Учреждение Российской академии медицинских наук Научно-исследовательский институт фармакологии имени В.В. Закусова РАМН
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Abstract

1. 2-Алкил-4,6-диметил-5-оксипиримидины общей формулы I: ! ! где Iа - R - изобутил, Iб - R- изопентил ! 2. Применение 2-изобутил-4,6-диметил-5-оксипиримидина (Iа) в качестве противоопухолевого и иммуномодулирующего средства 1. 2-Alkyl-4,6-dimethyl-5-hydroxypyrimidines of the general formula I:! ! where Ia - R - isobutyl, Ib - R - isopentyl! 2. The use of 2-isobutyl-4,6-dimethyl-5-hydroxypyrimidine (Ia) as an antitumor and immunomodulating agent

Claims (2)

1. 2-Алкил-4,6-диметил-5-оксипиримидины общей формулы I:1. 2-Alkyl-4,6-dimethyl-5-hydroxypyrimidines of the general formula I:
Figure 00000001
Figure 00000001
 где Iа - R - изобутил, Iб - R- изопентилwhere Ia - R - isobutyl, Ib - R - isopentyl 2. Применение 2-изобутил-4,6-диметил-5-оксипиримидина (Iа) в качестве противоопухолевого и иммуномодулирующего средства 2. The use of 2-isobutyl-4,6-dimethyl-5-hydroxypyrimidine (Ia) as an antitumor and immunomodulating agent
RU2011107831/04A 2011-03-01 2011-03-01 5-oxypyrimidine derivative possessing antineoplastic activity RU2518889C2 (en)

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RU2011107831/04A RU2518889C2 (en) 2011-03-01 2011-03-01 5-oxypyrimidine derivative possessing antineoplastic activity

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RU2011107831/04A RU2518889C2 (en) 2011-03-01 2011-03-01 5-oxypyrimidine derivative possessing antineoplastic activity

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RU2013145422/15A Substitution RU2013145422A (en) 2013-10-10 2013-10-10 5-Oxypyrimidine Derivative with Antitumor Activity
RU2013145423/04A Division RU2566445C2 (en) 2013-10-10 2013-10-10 5-oxypyrimidine derivatives possessing immunomodulatory activity

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RU2686672C1 (en) * 2018-07-20 2019-04-30 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" Agent with antitumour and antimetastatic activity, anti-inflammatory and antiallergic action

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SU1499883A1 (en) * 1987-11-24 1991-10-23 Научно-исследовательский институт фармакологии АМН СССР Dichlorhydrate 2,4-bis-(p-tret-butylanilino)-5-oxi-6-methylpyrimidine possessing analsetyc and antiflammatory activity
US20080221103A1 (en) * 2007-03-09 2008-09-11 Orchid Research Laboratories Ltd. New heterocyclic compounds

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