RU2007137396A - Эндопаразитицидное средство - Google Patents

Эндопаразитицидное средство Download PDF

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Publication number
RU2007137396A
RU2007137396A RU2007137396/15A RU2007137396A RU2007137396A RU 2007137396 A RU2007137396 A RU 2007137396A RU 2007137396/15 A RU2007137396/15 A RU 2007137396/15A RU 2007137396 A RU2007137396 A RU 2007137396A RU 2007137396 A RU2007137396 A RU 2007137396A
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RU
Russia
Prior art keywords
agent according
endoparasiticidal
solvent
endoparasiticidal agent
emodepside
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RU2007137396/15A
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English (en)
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RU2417101C2 (ru
Inventor
Венката-Рангарао КАНИКАНТИ (DE)
Венката-Рангарао КАНИКАНТИ
Михаэль ТРОЙБЕЛЬ (DE)
Михаэль Тройбель
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Байер ХельсКер АГ (DE)
Байер ХельсКер АГ
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Application filed by Байер ХельсКер АГ (DE), Байер ХельсКер АГ filed Critical Байер ХельсКер АГ (DE)
Publication of RU2007137396A publication Critical patent/RU2007137396A/ru
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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/84—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N2300/00—Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

1. Эндопаразитицидное средство, содержащее в качестве действующих веществ эмодепсид, а также празиквантел или эпсипрантел, и в качестве растворителя 1,2-изопропилиденглицерин, причем содержание воды в средстве составляет не более 1 вес.%. ! 2. Эндопаразитицидное средство по п.1, отличающееся тем, что в качестве действующих веществ оно содержит эмодепсид и празиквантел. ! 3. Эндопаразитицидное средство по п.1, отличающееся тем, что используемый растворитель содержит, по меньшей мере, 60 об.% 1,2-изопропилиденглицерина. ! 4. Эндопаразитицидное средство по пп.1-3, отличающееся тем, что оно содержит 1,2-изопропилиденглицерин в качестве единственного растворителя. ! 5. Метод получения эндопаразитицидного средства по пп.1-4, отличающийся тем, что действующие вещества смешивают с растворителями и при необходимости с дополнительными добавками. ! 6. Использование эмодепсида и празиквантела или эпсипрантела для получения эндопаразитицидного средства, которое содержит 1,2-изопропилиденглицерин в качестве растворителя, обнаруживает содержание воды не более 1 вес.% и годится для наружного применения для борьбы с эндопаразитами.

Claims (6)

1. Эндопаразитицидное средство, содержащее в качестве действующих веществ эмодепсид, а также празиквантел или эпсипрантел, и в качестве растворителя 1,2-изопропилиденглицерин, причем содержание воды в средстве составляет не более 1 вес.%.
2. Эндопаразитицидное средство по п.1, отличающееся тем, что в качестве действующих веществ оно содержит эмодепсид и празиквантел.
3. Эндопаразитицидное средство по п.1, отличающееся тем, что используемый растворитель содержит, по меньшей мере, 60 об.% 1,2-изопропилиденглицерина.
4. Эндопаразитицидное средство по пп.1-3, отличающееся тем, что оно содержит 1,2-изопропилиденглицерин в качестве единственного растворителя.
5. Метод получения эндопаразитицидного средства по пп.1-4, отличающийся тем, что действующие вещества смешивают с растворителями и при необходимости с дополнительными добавками.
6. Использование эмодепсида и празиквантела или эпсипрантела для получения эндопаразитицидного средства, которое содержит 1,2-изопропилиденглицерин в качестве растворителя, обнаруживает содержание воды не более 1 вес.% и годится для наружного применения для борьбы с эндопаразитами.
RU2007137396/15A 2005-03-11 2006-02-27 Эндопаразитицидное средство RU2417101C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005011779A DE102005011779A1 (de) 2005-03-11 2005-03-11 Endoparasitizide Mittel
DE102005011779.1 2005-03-11

Publications (2)

Publication Number Publication Date
RU2007137396A true RU2007137396A (ru) 2009-04-20
RU2417101C2 RU2417101C2 (ru) 2011-04-27

Family

ID=36216785

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2007137396/15A RU2417101C2 (ru) 2005-03-11 2006-02-27 Эндопаразитицидное средство

Country Status (31)

Country Link
US (1) US20080255037A1 (ru)
EP (1) EP1863535B1 (ru)
JP (2) JP5232635B2 (ru)
KR (3) KR101856817B1 (ru)
CN (2) CN101193657A (ru)
AR (2) AR053691A1 (ru)
AU (1) AU2006222314B2 (ru)
BR (1) BRPI0608287B1 (ru)
CA (1) CA2600638C (ru)
CR (1) CR9364A (ru)
DE (1) DE102005011779A1 (ru)
DK (1) DK1863535T3 (ru)
ES (1) ES2639394T3 (ru)
GT (1) GT200600106A (ru)
HR (1) HRP20171354T1 (ru)
HU (1) HUE036294T2 (ru)
IL (1) IL185856A (ru)
MX (1) MX2007010990A (ru)
MY (1) MY163037A (ru)
NO (1) NO342645B1 (ru)
NZ (1) NZ561754A (ru)
PE (1) PE20061071A1 (ru)
PL (1) PL1863535T3 (ru)
PT (1) PT1863535T (ru)
RU (1) RU2417101C2 (ru)
SI (1) SI1863535T1 (ru)
TW (1) TW200700085A (ru)
UA (1) UA94705C2 (ru)
UY (1) UY29417A1 (ru)
WO (1) WO2006094664A1 (ru)
ZA (1) ZA200707732B (ru)

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DE102004055316A1 (de) * 2004-11-16 2006-05-18 Bayer Healthcare Ag Verhinderung vertikaler Endoparasiten-Infektionen
DE102005011779A1 (de) * 2005-03-11 2006-09-14 Bayer Healthcare Ag Endoparasitizide Mittel
DE102009012423A1 (de) * 2009-03-10 2010-09-16 Bayer Animal Health Gmbh Zubereitung auf Ölbasis
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
KR101979049B1 (ko) * 2011-12-21 2019-05-15 바이엘 파마 악티엔게젤샤프트 무정형 에모뎁시드를 함유하는 제제
EP3480195A1 (en) 2017-11-07 2019-05-08 Bayer Animal Health GmbH Method for the synthesis of cyclic depsipeptides
JP2021501769A (ja) 2017-11-07 2021-01-21 バイエル・アニマル・ヘルス・ゲーエムベーハー 環状デプシペプチドを合成する方法
BR112022002623A2 (pt) 2019-08-14 2022-05-03 Vetoquinol Sa Composição, composição compreendendo praziquantel, emodepsida e um componente solvente, método para produzir uma composição e composição para uso
CN111346046B (zh) * 2020-03-06 2021-07-09 安徽农业大学 一种含莫西菌素注射用缓释凝胶制剂及制备方法

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Also Published As

Publication number Publication date
US20080255037A1 (en) 2008-10-16
KR20160148717A (ko) 2016-12-26
EP1863535B1 (de) 2017-06-07
HRP20171354T1 (hr) 2017-11-03
AU2006222314B2 (en) 2012-04-05
DK1863535T3 (en) 2017-09-25
CA2600638C (en) 2015-10-27
PT1863535T (pt) 2017-09-13
TW200700085A (en) 2007-01-01
MX2007010990A (es) 2007-11-07
NO342645B1 (no) 2018-06-25
NO20075039L (no) 2007-10-05
IL185856A (en) 2016-06-30
HUE036294T2 (hu) 2018-06-28
UA94705C2 (ru) 2011-06-10
AR053691A1 (es) 2007-05-16
DE102005011779A1 (de) 2006-09-14
MY163037A (en) 2017-08-15
NZ561754A (en) 2010-11-26
UY29417A1 (es) 2006-10-31
JP5232635B2 (ja) 2013-07-10
RU2417101C2 (ru) 2011-04-27
ZA200707732B (en) 2009-06-24
KR20140043946A (ko) 2014-04-11
AU2006222314A1 (en) 2006-09-14
KR101856817B1 (ko) 2018-05-10
JP2008532959A (ja) 2008-08-21
AR110174A2 (es) 2019-03-06
KR20070119673A (ko) 2007-12-20
SI1863535T1 (sl) 2017-10-30
GT200600106A (es) 2006-11-07
IL185856A0 (en) 2008-01-06
CN102908609A (zh) 2013-02-06
ES2639394T3 (es) 2017-10-26
BRPI0608287B1 (pt) 2020-03-24
PE20061071A1 (es) 2006-11-30
BRPI0608287A2 (pt) 2009-12-22
CN101193657A (zh) 2008-06-04
WO2006094664A1 (de) 2006-09-14
JP2013079268A (ja) 2013-05-02
CR9364A (es) 2008-02-12
PL1863535T3 (pl) 2017-10-31
EP1863535A1 (de) 2007-12-12
CA2600638A1 (en) 2006-09-14

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