RS57842B1 - Modifikovana sulfamidaza i njena proizvodnja - Google Patents

Modifikovana sulfamidaza i njena proizvodnja

Info

Publication number
RS57842B1
RS57842B1 RS20181119A RSP20181119A RS57842B1 RS 57842 B1 RS57842 B1 RS 57842B1 RS 20181119 A RS20181119 A RS 20181119A RS P20181119 A RSP20181119 A RS P20181119A RS 57842 B1 RS57842 B1 RS 57842B1
Authority
RS
Serbia
Prior art keywords
production
modified sulfamidase
sulfamidase
modified
Prior art date
Application number
RS20181119A
Other languages
English (en)
Inventor
Charlotta Berghard
Erik Nordling
Gelius Stefan Svensson
Agneta Tjernberg
Original Assignee
Swedish Orphan Biovitrum Ab Publ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Swedish Orphan Biovitrum Ab Publ filed Critical Swedish Orphan Biovitrum Ab Publ
Publication of RS57842B1 publication Critical patent/RS57842B1/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y310/00—Hydrolases acting on sulfur-nitrogen bonds (3.10)
    • C12Y310/01—Hydrolases acting on sulfur-nitrogen bonds (3.10) acting on sulfur-nitrogen bonds (3.10.1)
    • C12Y310/01001—N-Sulfoglucosamine sulfohydrolase (3.10.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RS20181119A 2014-04-01 2015-04-01 Modifikovana sulfamidaza i njena proizvodnja RS57842B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14162996 2014-04-01
PCT/EP2015/057256 WO2015150490A1 (en) 2014-04-01 2015-04-01 Modified sulfamidase and production thereof
EP15713502.1A EP2970413B1 (en) 2014-04-01 2015-04-01 Modified sulfamidase and production thereof

Publications (1)

Publication Number Publication Date
RS57842B1 true RS57842B1 (sr) 2018-12-31

Family

ID=50389999

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20181119A RS57842B1 (sr) 2014-04-01 2015-04-01 Modifikovana sulfamidaza i njena proizvodnja

Country Status (30)

Country Link
US (2) US9982243B2 (sr)
EP (2) EP2970413B1 (sr)
JP (1) JP6594896B2 (sr)
KR (1) KR20160138282A (sr)
CN (1) CN106414727A (sr)
AU (1) AU2015239126B2 (sr)
BR (1) BR112016022333A2 (sr)
CA (1) CA2943140A1 (sr)
CL (1) CL2016002469A1 (sr)
CY (1) CY1120697T1 (sr)
DK (1) DK2970413T3 (sr)
ES (1) ES2687262T3 (sr)
HK (1) HK1231510A1 (sr)
HR (1) HRP20181507T1 (sr)
HU (1) HUE039691T2 (sr)
IL (1) IL247978A0 (sr)
LT (1) LT2970413T (sr)
MA (1) MA38816B1 (sr)
MX (1) MX368947B (sr)
PH (1) PH12016501812A1 (sr)
PL (1) PL2970413T3 (sr)
PT (1) PT2970413T (sr)
RS (1) RS57842B1 (sr)
RU (1) RU2708026C2 (sr)
SA (1) SA516371859B1 (sr)
SG (1) SG11201608025QA (sr)
SI (1) SI2970413T1 (sr)
UA (1) UA120432C2 (sr)
WO (1) WO2015150490A1 (sr)
ZA (1) ZA201606492B (sr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2708026C2 (ru) 2014-04-01 2019-12-03 Свидиш Орфан Биовитрум Аб (Пабл) Модифицированная сульфамидаза и способ её получения
JP2018535654A (ja) * 2015-10-01 2018-12-06 スウェディッシュ オーファン バイオビトラム アクティエボラーグ （ペーウーベーエル） 修飾リソソームタンパク質とその製造
EP3692070A1 (en) 2017-10-02 2020-08-12 Denali Therapeutics Inc. Fusion proteins comprising enzyme replacement therapy enzymes
WO2019145500A1 (en) 2018-01-26 2019-08-01 Swedish Orphan Biovitrum Ab (Publ) Method of treatment
US11708569B2 (en) 2018-08-29 2023-07-25 University Of Copenhagen Modified recombinant lysosomal alpha-galactosidase A and aspartylglucoaminidase having low mannose-6-phosphate and high sialic acid
EP3741867A1 (en) 2019-05-24 2020-11-25 Swedish Orphan Biovitrum AB (Publ) Sulfatase activity assay
EP4229192A1 (en) 2020-10-14 2023-08-23 Denali Therapeutics Inc. Fusion proteins comprising sulfoglucosamine sulfohydrolase enzymes and methods thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863782A (en) 1995-04-19 1999-01-26 Women's And Children's Hospital Synthetic mammalian sulphamidase and genetic sequences encoding same
EP1378525A3 (en) 1996-06-07 2004-01-14 Neorx Corporation Humanized antibodies that bind to the antigen bound by antibody NR-LU-13 and their use in pretargeting methods
US7560424B2 (en) 2001-04-30 2009-07-14 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US8008252B2 (en) 2001-10-10 2011-08-30 Novo Nordisk A/S Factor VII: remodeling and glycoconjugation of Factor VII
IL161352A0 (en) 2001-10-16 2004-09-27 Symbiontics Inc Methods and compositions for targeting underglycosylated proteins across the blood brain barrier
NZ537306A (en) 2002-07-01 2008-11-28 Kenneth S Warren Inst Inc Compositions comprising mutein recombinant tissue protective cytokines having one or more amino acid substitutions facilitating transport of a molecule via transcytosis across an endothelial cell barrier
CA2680189A1 (en) * 2007-03-06 2008-09-12 Saint Louis University Modified enzyme and treatment method
KR101744142B1 (ko) * 2008-01-18 2017-06-07 바이오마린 파머수티컬 인크. 활성이고 높은 정도로 인산화된 인간 리소좀 술파타아제 효소의 제조 및 그 용도
EP2394667A1 (en) * 2010-06-10 2011-12-14 Laboratorios Del Dr. Esteve, S.A. Vectors and sequences for the treatment of diseases
WO2012085622A1 (en) 2010-12-22 2012-06-28 Fondazione Telethon Therapeutic strategies to treat cns pathology in mucopolysaccharidoses
WO2012177778A1 (en) * 2011-06-20 2012-12-27 Mount Sinai School Of Medicine Anti-tnf- therapy for the mucopolysaccharidoses and other lysosomal disorders
WO2014194427A1 (en) 2013-06-06 2014-12-11 Angiochem Inc. Targeted iduronate-2-sulfatase fusion proteins
US20140377246A1 (en) 2013-06-19 2014-12-25 Carol Ann Foundation and International Morquio Organization Enzyme replacement therapy for treating mps vii related bone lesions using a chemically modified enzyme
RU2708026C2 (ru) 2014-04-01 2019-12-03 Свидиш Орфан Биовитрум Аб (Пабл) Модифицированная сульфамидаза и способ её получения

Also Published As

Publication number Publication date
SG11201608025QA (en) 2016-10-28
RU2016140844A (ru) 2018-05-10
JP2017514462A (ja) 2017-06-08
MA38816A (fr) 2016-01-20
EP3401325A1 (en) 2018-11-14
KR20160138282A (ko) 2016-12-02
SA516371859B1 (ar) 2019-01-17
CN106414727A (zh) 2017-02-15
WO2015150490A1 (en) 2015-10-08
AU2015239126A1 (en) 2016-10-27
MA38816B1 (fr) 2018-10-31
PL2970413T3 (pl) 2018-12-31
HRP20181507T1 (hr) 2018-11-16
US20160230155A1 (en) 2016-08-11
MX368947B (es) 2019-10-22
CA2943140A1 (en) 2015-10-08
PH12016501812A1 (en) 2017-07-24
HUE039691T2 (hu) 2019-01-28
SI2970413T1 (sl) 2018-10-30
AU2015239126B2 (en) 2019-05-02
JP6594896B2 (ja) 2019-10-23
RU2708026C2 (ru) 2019-12-03
BR112016022333A2 (pt) 2017-08-15
MX2016012910A (es) 2017-07-14
PT2970413T (pt) 2018-10-23
HK1231510A1 (zh) 2017-12-22
DK2970413T3 (en) 2018-10-15
LT2970413T (lt) 2018-10-10
EP2970413A1 (en) 2016-01-20
CL2016002469A1 (es) 2017-12-15
UA120432C2 (uk) 2019-12-10
US20180320152A1 (en) 2018-11-08
ES2687262T3 (es) 2018-10-24
RU2016140844A3 (sr) 2018-10-11
US9982243B2 (en) 2018-05-29
IL247978A0 (en) 2016-11-30
CY1120697T1 (el) 2019-12-11
ZA201606492B (en) 2019-02-27
EP2970413B1 (en) 2018-07-04

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