RS51261B - Derivati purina kao agonisti receptora adenozina a1 i postupci za njihovu upotrebu - Google Patents
Derivati purina kao agonisti receptora adenozina a1 i postupci za njihovu upotrebuInfo
- Publication number
- RS51261B RS51261B RSP-2010/0241A RSP20100241A RS51261B RS 51261 B RS51261 B RS 51261B RS P20100241 A RSP20100241 A RS P20100241A RS 51261 B RS51261 B RS 51261B
- Authority
- RS
- Serbia
- Prior art keywords
- methods
- animal
- adenosine
- purine derivatives
- receptor agonists
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/167—Purine radicals with ribosyl as the saccharide radical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/12—Triazine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57480504P | 2004-05-26 | 2004-05-26 | |
US58826304P | 2004-07-15 | 2004-07-15 | |
PCT/US2005/018381 WO2005117910A2 (en) | 2004-05-26 | 2005-05-25 | Purine derivatives as adenosine a1 receptor agonists and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
RS51261B true RS51261B (sr) | 2010-12-31 |
Family
ID=35463332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RSP-2010/0241A RS51261B (sr) | 2004-05-26 | 2005-05-25 | Derivati purina kao agonisti receptora adenozina a1 i postupci za njihovu upotrebu |
Country Status (25)
Country | Link |
---|---|
US (3) | US7423144B2 (sr) |
EP (2) | EP2221307A1 (sr) |
JP (3) | JP4484928B2 (sr) |
KR (2) | KR101267202B1 (sr) |
CN (1) | CN103087133B (sr) |
AT (1) | ATE462704T1 (sr) |
AU (1) | AU2005249430B2 (sr) |
BR (1) | BRPI0510406A (sr) |
CA (1) | CA2567289C (sr) |
CY (1) | CY1110159T1 (sr) |
DE (1) | DE602005020286D1 (sr) |
DK (1) | DK1758596T3 (sr) |
EA (1) | EA011826B1 (sr) |
ES (1) | ES2343421T3 (sr) |
HK (1) | HK1104457A1 (sr) |
HR (1) | HRP20100344T2 (sr) |
IL (1) | IL179400A (sr) |
ME (1) | ME01072B (sr) |
MX (1) | MXPA06013560A (sr) |
NO (1) | NO339450B1 (sr) |
NZ (1) | NZ551951A (sr) |
PL (1) | PL1758596T3 (sr) |
PT (1) | PT1758596E (sr) |
RS (1) | RS51261B (sr) |
WO (1) | WO2005117910A2 (sr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4484928B2 (ja) * | 2004-05-26 | 2010-06-16 | イノテック ファーマシューティカルズ コーポレイション | アデノシンa1レセプター・アゴニストとしてのプリン誘導体およびその使用方法 |
MX2007003271A (es) * | 2004-09-20 | 2007-06-05 | Inotek Pharmaceuticals Corp | Derivados de purina y metodos de uso de los mismos. |
EP1962597A4 (en) * | 2005-11-30 | 2008-12-17 | Inotek Pharmaceuticals Corp | PURINE DERIVATIVES AND METHOD OF USE |
US20070238694A1 (en) * | 2006-03-23 | 2007-10-11 | Inotek Pharmaceuticals Corporation | Purine compounds and methods of use thereof |
SI2001456T1 (sl) * | 2006-04-04 | 2010-04-30 | Emodys Gmbh | Uporaba zmesi, ki vsebuje antagonist na opioidnem kapa receptorju za zdravljenje disocialnih bolezni |
HUE028068T2 (en) | 2009-05-01 | 2016-11-28 | Inotek Pharmaceuticals Corp | A method for reducing the pressure in a human patient |
US8263762B2 (en) | 2009-06-30 | 2012-09-11 | Dogwood Pharmaceuticals, Inc. | Alkoxy-carbonyl-amino-alkynyl-adenosine compounds and derivatives thereof as A2AR agonists |
CN102665730A (zh) * | 2009-10-26 | 2012-09-12 | 伊诺泰克制药公司 | 眼用制剂及其制造方法 |
EA025415B1 (ru) | 2010-01-11 | 2016-12-30 | Инотек Фармасьютикалз Корпорейшн | Комбинация, набор и способ снижения внутриглазного давления |
PL2555775T3 (pl) * | 2010-03-19 | 2017-08-31 | Inotek Pharmaceuticals Corporation | Kompozycje połączenia agonistów receptora adenozyny A<sub>1</sub> i inhibitorów anhydrazy węglanowej do obniżania ciśnienia wewnątrzgałkowego |
WO2011116292A1 (en) | 2010-03-19 | 2011-09-22 | Inotek Pharmaceuticals Corporation | Combination compositions of adenosine a1 agonists and non-selective beta-adrenergic receptor blockers for reducing intraocular pressure |
JP2013523738A (ja) | 2010-03-26 | 2013-06-17 | イノテック ファーマシューティカルズ コーポレイション | アデノシン化合物およびそれらの使用 |
EP2569325A4 (en) | 2010-03-26 | 2013-10-09 | Inotek Pharmaceuticals Corp | METHOD FOR REDUCING INTRAOCULAR PRESSURE IN HUMANS USING N6-CYCLOPENTYLADENOSINE (CPA) DERIVATIVES OR CPA PRODRUGS |
JP2015508751A (ja) | 2012-01-26 | 2015-03-23 | イノテック ファーマシューティカルズ コーポレイション | [(2r,3s,4r,5r)−5−(6−(シクロペンチルアミノ)−9h−プリン−9−イル)−3,4−ジヒドロキシテトラヒドロフラン−2−イル]メチルナイトレートの無水多形体及びその製造方法 |
MX2015013234A (es) | 2013-03-15 | 2016-04-15 | Inotek Pharmaceuticals Corp | Formulaciones oftalmicas. |
GB2582361A (en) * | 2019-03-21 | 2020-09-23 | Univ Warwick | Adenosine receptor agonists |
DE102021120112A1 (de) | 2021-08-03 | 2023-02-09 | Bayerische Motoren Werke Aktiengesellschaft | Schnittwerkzeug für ein Metallblech und ein Verfahren zum Betreiben eines Schnittwerkzeugs für ein Metallblech |
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WO1994002497A1 (en) * | 1992-07-15 | 1994-02-03 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Sulfo-derivatives of adenosine |
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CN1164122A (zh) | 1996-03-01 | 1997-11-05 | 株式会社日立制作所 | 等离子处理机及其处理方法 |
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