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Postupak za sintetisanje deoksibiotinil heksametilendiamin-DOTA koji obuhvata reakciju biotinil heksametilendiamina sa tri-f-butil-DOTA u prisustvu benzotriazol-1-il-oksitripirolidinofosfonijum heksafluorofosfata, kao kondenzujućeg sredstva i trietilamina, kao baze.Prijava sadrži još 3 patentna zahteva.A process for the synthesis of deoxybiotinyl hexamethylenediamine-DOTA comprising the reaction of biotinyl hexamethylenediamine with tri-t-butyl-DOTA in the presence of benzotriazol-1-yl-oxytri pyrrolidinophosphonium hexafluorophosphate as a condensing agent and a further triethylamine.
RSP-2009/0250A2005-06-302006-05-31Synthesis of deoxybiotinyl hexamethylenediamine-dota
RS50816B
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