PT994119E - Processo estereosselectivo para a preparacao do epimero 22r de budesonide - Google Patents

Processo estereosselectivo para a preparacao do epimero 22r de budesonide

Info

Publication number
PT994119E
PT994119E PT99120330T PT99120330T PT994119E PT 994119 E PT994119 E PT 994119E PT 99120330 T PT99120330 T PT 99120330T PT 99120330 T PT99120330 T PT 99120330T PT 994119 E PT994119 E PT 994119E
Authority
PT
Portugal
Prior art keywords
budesonide
alpha
preparation
epimero
iodo
Prior art date
Application number
PT99120330T
Other languages
English (en)
Inventor
Filippo La Loggia
Pierfranco Dotti
Original Assignee
Farmabios Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmabios Spa filed Critical Farmabios Spa
Publication of PT994119E publication Critical patent/PT994119E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT99120330T 1998-10-13 1999-10-12 Processo estereosselectivo para a preparacao do epimero 22r de budesonide PT994119E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002196A IT1302657B1 (it) 1998-10-13 1998-10-13 Processo stereoselettivo per la preparazione di budesonide nella formadi epimero 22-r.

Publications (1)

Publication Number Publication Date
PT994119E true PT994119E (pt) 2004-08-31

Family

ID=11380860

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99120330T PT994119E (pt) 1998-10-13 1999-10-12 Processo estereosselectivo para a preparacao do epimero 22r de budesonide

Country Status (8)

Country Link
EP (1) EP0994119B1 (pt)
JP (1) JP2000128897A (pt)
AT (1) ATE263184T1 (pt)
DE (1) DE69915965T2 (pt)
DK (1) DK0994119T3 (pt)
ES (1) ES2218929T3 (pt)
IT (1) IT1302657B1 (pt)
PT (1) PT994119E (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0012260D0 (en) * 2000-05-19 2000-07-12 Astrazeneca Ab Novel composition
JP2011513469A (ja) * 2008-03-13 2011-04-28 ファルマビオス ソシエタ ペル アチオニ プレグナン誘導体の製造法
CN111018932B (zh) * 2019-11-28 2021-07-02 奥锐特药业股份有限公司 一种甾体化合物9-位脱卤的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
SE8604059D0 (sv) * 1986-09-25 1986-09-25 Astra Pharma Prod A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives
FR2675146A1 (fr) * 1991-04-10 1992-10-16 Roussel Uclaf Nouveaux derives sterouides de la pregna-1,4-diene-3,20-dione, leur preparation, leur application a la preparation de derives 16,17-methylene dioxy substitues et nouveaux intermediaires.
IT1291288B1 (it) * 1997-04-30 1999-01-07 Farmabios Srl Processo per la preparazione di 16,17 acetali di derivati pregnanici con controllo della distribuzione epimerica al c-22.

Also Published As

Publication number Publication date
DE69915965D1 (de) 2004-05-06
JP2000128897A (ja) 2000-05-09
ATE263184T1 (de) 2004-04-15
ITMI982196A1 (it) 2000-04-13
IT1302657B1 (it) 2000-09-29
EP0994119A1 (en) 2000-04-19
DE69915965T2 (de) 2005-03-17
DK0994119T3 (da) 2004-08-02
EP0994119B1 (en) 2004-03-31
ES2218929T3 (es) 2004-11-16

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