PT979244E - Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem - Google Patents

Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem

Info

Publication number: PT979244E
Authority: PT; Portugal
Prior art keywords: contain; preparation; pharmaceutical compositions; cyclosporin derivatives; radical
Prior art date: 1997-04-30

Application number

PT98922872T

Other languages

English (en)

Inventor

Serge Mignani

Jean-Claude Barriere

Jean-Christophe Carry

Michel Evers

Bruno Filoche

Georges Bashiardes

Claude Bensoussan

Jean-Christophe Gueguen

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-30

Filing date

1998-04-27

Publication date

2005-06-30

1998-04-27 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2005-06-30 Publication of PT979244E publication Critical patent/PT979244E/pt

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
208000005074 Retroviridae Infections Diseases 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
Molecular Biology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Immunology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

PT98922872T 1997-04-30 1998-04-27 Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem PT979244E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9705351A FR2762843B1 (fr)	1997-04-30	1997-04-30	Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
PT979244E true PT979244E (pt)	2005-06-30

Family

ID=9506467

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT98922872T PT979244E (pt)	1997-04-30	1998-04-27	Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem

Country Status (13)

Country	Link
US (1)	US5977067A (pt)
EP (1)	EP0979244B1 (pt)
JP (1)	JP2001524105A (pt)
AT (1)	ATE290015T1 (pt)
AU (1)	AU7535798A (pt)
DE (1)	DE69829175T2 (pt)
ES (1)	ES2236902T3 (pt)
FR (1)	FR2762843B1 (pt)
MA (1)	MA26488A1 (pt)
PT (1)	PT979244E (pt)
TN (1)	TNSN98057A1 (pt)
WO (1)	WO1998049193A1 (pt)
ZA (1)	ZA983618B (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2002333098B2 (en) *	2001-10-19	2006-03-16	Isotechnika Pharma Inc.	Novel cyclosporin analog microemulsion preconcentrates
WO2003033526A2 (en)	2001-10-19	2003-04-24	Isotechnika Inc.	Synthesis of cyclosporin analogs
KR20040039622A (ko) *	2002-11-04	2004-05-12	주식회사 엘지생활건강	모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
CN102268094A (zh) *	2002-08-30	2011-12-07	比奥雷克西斯药物公司	被修饰的转铁蛋白抗体的融合蛋白
US20050123514A1 (en) *	2003-05-05	2005-06-09	Brian Davis	Increased transduction using ABC transporter substrates and/or inhibitors
CA2583494C (en) *	2004-10-01	2014-01-21	Scynexis, Inc.	3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis c infection
US7196161B2 (en) *	2004-10-01	2007-03-27	Scynexis Inc.	3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
EP1931696B1 (en) *	2005-09-30	2011-02-16	Scynexis, Inc.	Arylalkyl and heteroarylalkyl derivatives of cyclosporine a for the treatment and prevention of viral infection
KR20080059270A (ko) *	2005-09-30	2008-06-26	싸이넥시스, 인크.	Ｃ형 간염 감염의 치료 및 예방을 위한 방법 및 제약조성물
US7745400B2 (en) *	2005-10-14	2010-06-29	Gregg Feinerman	Prevention and treatment of ocular side effects with a cyclosporin
EP1937290A1 (en) *	2005-10-14	2008-07-02	Allergan, Inc.	Prevention and treatment of drug-associated ocular side effects with a cyclosporin
US9839667B2 (en)	2005-10-14	2017-12-12	Allergan, Inc.	Prevention and treatment of ocular side effects with a cyclosporin
DE602007013391D1 (de)	2006-05-19	2011-05-05	Scynexis Inc	Cyclosporins zur behandlung und vorbeugung von augenerkrankungen
JP2009539292A (ja) *	2006-06-02	2009-11-12	ぺリション、クロード、アニー	活性電子の管理
WO2008069917A2 (en)	2006-11-20	2008-06-12	Scynexis, Inc.	Novel cyclic peptides
US20080255038A1 (en) *	2007-04-11	2008-10-16	Samuel Earl Hopkins	Pharmaceutical compositions
CN102083852A (zh)	2008-06-06	2011-06-01	西尼克斯公司	环孢菌素类似物及其在治疗hcv感染中的应用
WO2009148615A1 (en) *	2008-06-06	2009-12-10	Scynexis, Inc.	Cyclosporin analogs and their use in the treatment of hcv infections
NZ590517A (en) *	2008-07-30	2012-12-21	Isotechnika Pharma Inc	Nonimmunosuppressive cyclosporine analogue molecules
DE102008060549A1 (de)	2008-12-04	2010-06-10	MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.	Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung
CA2748389A1 (en)	2008-12-31	2010-07-08	Scynexis, Inc.	Derivatives of cyclosporin a
EP2391376A4 (en)	2009-01-30	2012-08-01	Enanta Pharm Inc	ANALOGUES OF CYCLOSPORIN FOR PREVENTING OR TREATING HEPATITIS C INFECTION
US8481483B2 (en) *	2009-02-19	2013-07-09	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
JP2012528163A (ja) *	2009-05-27	2012-11-12	アラーガン、インコーポレイテッド	炎症性疾患および状態を処置するためのシクロスポリン誘導体
US20100305047A1 (en) *	2009-05-27	2010-12-02	Allergan, Inc.	Cyclosporin derivatives for enhancing the growth of hair
US8685917B2 (en) *	2009-07-09	2014-04-01	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
KR20120125610A (ko)	2009-12-30	2012-11-16	싸이넥시스, 인크.	시클로스포린 유사체
US9175042B2 (en)	2010-10-12	2015-11-03	Allergan, Inc.	Cyclosporin analogs
SG189880A1 (en)	2010-10-12	2013-06-28	Allergan Inc	Cyclosporin analogs
AU2011342284C1 (en)	2010-12-15	2017-07-13	Contravir Pharmaceuticals, Inc.	Cyclosporine analogue molecules modified at amino acid 1 and 3
DE102011111991A1 (de) *	2011-08-30	2013-02-28	Lead Discovery Center Gmbh	Neue Cyclosporin-Derivate
EP2705856A1 (en)	2012-09-07	2014-03-12	Deutsches Zentrum für Neurodegenerative Erkrankungen e.V.	Compounds for the treatment of neurodegenerative disorders
WO2014049540A2 (en)	2012-09-29	2014-04-03	Novartis Ag	Cyclic peptides and use as medicines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0194972B1 (en) *	1985-03-11	1992-07-29	Sandoz Ag	Novel cyclosporins
US4814323A (en) *	1986-03-25	1989-03-21	Andrieu J M	Process for the treatment and the prevention of AIDS and other disorders induced by the LAV/HTLV III virus
US4798823A (en) *	1987-06-03	1989-01-17	Merck & Co., Inc.	New cyclosporin analogs with modified "C-9 amino acids"
US4885276A (en) *	1987-06-03	1989-12-05	Merck & Co., Inc.	Cyclosporin analogs with modified "C-9 amino acids"
DK0484281T4 (da) *	1990-11-02	2001-02-05	Novartis Ag	Cyclosporiner
US5512555A (en) *	1994-07-21	1996-04-30	Merck & Co., Inc.	Method of treating sweat-related conditions using finasteride, epristeride and a cholestan-3-one
KR100441220B1 (ko) *	1995-07-17	2005-02-24	체-헴 아게	항-hiv효과를갖는사이클로스포린유도체

1997
- 1997-04-30 FR FR9705351A patent/FR2762843B1/fr not_active Expired - Fee Related
1998
- 1998-04-27 ES ES98922872T patent/ES2236902T3/es not_active Expired - Lifetime
- 1998-04-27 AU AU75357/98A patent/AU7535798A/en not_active Abandoned
- 1998-04-27 EP EP98922872A patent/EP0979244B1/fr not_active Expired - Lifetime
- 1998-04-27 PT PT98922872T patent/PT979244E/pt unknown
- 1998-04-27 DE DE69829175T patent/DE69829175T2/de not_active Expired - Lifetime
- 1998-04-27 WO PCT/FR1998/000838 patent/WO1998049193A1/fr active IP Right Grant
- 1998-04-27 MA MA25048A patent/MA26488A1/fr unknown
- 1998-04-27 AT AT98922872T patent/ATE290015T1/de active
- 1998-04-27 JP JP54666498A patent/JP2001524105A/ja active Pending
- 1998-04-29 ZA ZA983618A patent/ZA983618B/xx unknown
- 1998-04-29 TN TNTNSN98057A patent/TNSN98057A1/fr unknown
- 1998-04-30 US US09/069,959 patent/US5977067A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0979244A1 (fr)	2000-02-16
DE69829175D1 (de)	2005-04-07
EP0979244B1 (fr)	2005-03-02
AU7535798A (en)	1998-11-24
WO1998049193A1 (fr)	1998-11-05
FR2762843B1 (fr)	1999-12-10
DE69829175T2 (de)	2006-02-16
ZA983618B (en)	1998-11-04
FR2762843A1 (fr)	1998-11-06
MA26488A1 (fr)	2004-12-20
JP2001524105A (ja)	2001-11-27
US5977067A (en)	1999-11-02
ES2236902T3 (es)	2005-07-16
ATE290015T1 (de)	2005-03-15
TNSN98057A1 (fr)	2005-03-15

Publication	Publication Date	Title
PT979244E (pt)	2005-06-30	Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem
PT948527E (pt)	2002-11-29	Novos derivados de ciclosporina sua preparacao e composicoes farmaceuticas que os contem
PT951474E (pt)	2002-11-29	Novos derivados da ciclosporina sua preparacao e composicoes farmaceuticas que os contem
TR200200579T2 (tr)	2002-12-23	Amino-tirazolpiridin türevleri.
BR0215240A (pt)	2004-10-26	Derivados de calcona e seu uso no tratamento de doenças
BR0008059A (pt)	2002-03-26	Composições de valdecoxib
SE9504661D0 (sv)	1995-12-22	New compounds
KR0141913B1 (en)	1998-06-01	Anti-virus agents
ATE108437T1 (de)	1994-07-15	Substituierte diaminophthalimide und analoga.
FI972434A (fi)	1997-06-09	Lamotrigiiniä sisältävä farmaseuttinen koostumus
MD1560G2 (ro)	2001-07-31	Compuşi ciclici, compoziţii farmaceutice pe baza lor şi metode de tratament al infecţiilor sau bolilor provocate de retrovirusuri
DK0387821T3 (da)	1994-09-19	2-Alkyl-4-arylmethylchinoliner, deres anvendelse og lægemidler fremstillet hermed
GR3019274T3 (en)	1996-06-30	Substituted 3-piperazinylalkyl-2,3-dihydro-4H-1,3-benzoxazine-4-ones, their preparation and their therapeutical use
PH27446A (en)	1993-07-02	Compound with gastric acid inhibitory effect
SE9504662D0 (sv)	1995-12-22	New compounds
MY121604A (en)	2006-02-28	Combination therapy for hiv infection using the hiv protease inhibitor indinavir and the reverse transcriptase inhibitor 3tc together with azt
BR0011845A (pt)	2002-03-05	Complexo farmacêutico
EP1411956B8 (en)	2005-10-05	Use of oversulfated polysaccharides as inhibitors of hiv
IL112110A0 (en)	1995-03-15	Octahydro-1h-isoindoles and pharmaceutical compositions containing them
BR0213463A (pt)	2004-11-09	Composições farmacêuticas contendo macrólidos
KR960700053A (ko)	1996-01-19	방사선회복제로서 리루졸의 이용(application of riluzole as a radiorestorer)