PT979244E - Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem - Google Patents

Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem

Info

Publication number: PT979244E
Authority: PT; Portugal
Prior art keywords: contain; preparation; pharmaceutical compositions; cyclosporin derivatives; radical
Prior art date: 1997-04-30

Application number

PT98922872T

Other languages

English (en)

Inventor

Serge Mignani

Jean-Claude Barriere

Jean-Christophe Carry

Michel Evers

Bruno Filoche

Georges Bashiardes

Claude Bensoussan

Jean-Christophe Gueguen

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-30

Filing date

1998-04-27

Publication date

2005-06-30

1998-04-27 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2005-06-30 Publication of PT979244E publication Critical patent/PT979244E/pt

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
208000005074 Retroviridae Infections Diseases 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Virology (AREA)
Veterinary Medicine (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

PT98922872T 1997-04-30 1998-04-27 Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem PT979244E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9705351A FR2762843B1 (fr)	1997-04-30	1997-04-30	Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
PT979244E true PT979244E (pt)	2005-06-30

Family

ID=9506467

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT98922872T PT979244E (pt)	1997-04-30	1998-04-27	Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem

Country Status (13)

Country	Link
US (1)	US5977067A (pt)
EP (1)	EP0979244B1 (pt)
JP (1)	JP2001524105A (pt)
AT (1)	ATE290015T1 (pt)
AU (1)	AU7535798A (pt)
DE (1)	DE69829175T2 (pt)
ES (1)	ES2236902T3 (pt)
FR (1)	FR2762843B1 (pt)
MA (1)	MA26488A1 (pt)
PT (1)	PT979244E (pt)
TN (1)	TNSN98057A1 (pt)
WO (1)	WO1998049193A1 (pt)
ZA (1)	ZA983618B (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2461740C (en)	2001-10-19	2013-02-12	Isotechnika Inc.	Synthesis of cyclosporin analogs
DK1435910T3 (da) *	2001-10-19	2009-11-09	Isotechnika Inc	Nye cyclosporinanaloge mikroemulsionsprækoncentrater
KR20040039622A (ko) *	2002-11-04	2004-05-12	주식회사 엘지생활건강	모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
US20060130158A1 (en) *	2002-08-30	2006-06-15	Turner Andrew J	Modified transferrin fusion proteins comprising duplicate transferrin amino or carboxy terminal domains
ATE488252T1 (de) *	2003-05-05	2010-12-15	Virxsys Corp	Erhöhte transduktion mit abc- transportersubstratenhemmern
US7196161B2 (en) *	2004-10-01	2007-03-27	Scynexis Inc.	3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
PT1802650E (pt) *	2004-10-01	2011-12-30	Scynexis Inc	Derivados da ciclosporina 3-éter e 3-tioéter substituída para o tratamento e prevenção da infecção de hepatite c
KR20080059270A (ko) *	2005-09-30	2008-06-26	싸이넥시스, 인크.	Ｃ형 간염 감염의 치료 및 예방을 위한 방법 및 제약조성물
WO2007041631A1 (en) *	2005-09-30	2007-04-12	Scynexis, Inc.	ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION
AU2006304143A1 (en) *	2005-10-14	2007-04-26	Allergan, Inc.	Prevention and treatment of drug-associated ocular side effects with a cyclosporin
US7745400B2 (en) *	2005-10-14	2010-06-29	Gregg Feinerman	Prevention and treatment of ocular side effects with a cyclosporin
US9839667B2 (en)	2005-10-14	2017-12-12	Allergan, Inc.	Prevention and treatment of ocular side effects with a cyclosporin
ATE502633T1 (de)	2006-05-19	2011-04-15	Scynexis Inc	Cyclosporins zur behandlung und vorbeugung von augenerkrankungen
WO2007141395A1 (fr) *	2006-06-02	2007-12-13	Claude Annie Perrichon	Gestion des electrons actifs
US7576057B2 (en)	2006-11-20	2009-08-18	Scynexis, Inc.	Cyclic peptides
US20080255038A1 (en) *	2007-04-11	2008-10-16	Samuel Earl Hopkins	Pharmaceutical compositions
US20090306033A1 (en) *	2008-06-06	2009-12-10	Keqiang Li	Novel cyclic peptides
CN102083852A (zh)	2008-06-06	2011-06-01	西尼克斯公司	环孢菌素类似物及其在治疗hcv感染中的应用
MX2011001152A (es) *	2008-07-30	2011-06-09	Isotechnika Pharma Inc	Moleculas de analogo de ciclosporina no-inmunesupresoras.
DE102008060549A1 (de)	2008-12-04	2010-06-10	MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.	Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung
US8536114B2 (en)	2008-12-31	2013-09-17	Scynexis, Inc.	Macrocycles
CA2751210C (en)	2009-01-30	2015-04-21	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues for preventing or treating hepatitis c infection
US8481483B2 (en) *	2009-02-19	2013-07-09	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
US20100305047A1 (en) *	2009-05-27	2010-12-02	Allergan, Inc.	Cyclosporin derivatives for enhancing the growth of hair
CA2763207A1 (en) *	2009-05-27	2010-12-02	Allergan, Inc.	Cyclosporin derivatives for treating inflammatory diseases and conditions
US8685917B2 (en) *	2009-07-09	2014-04-01	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
CA2785978A1 (en)	2009-12-30	2011-07-07	Scynexis, Inc.	Cyclosporine analogues
WO2012051193A1 (en)	2010-10-12	2012-04-19	Allergan, Inc.	Cyclosporin analogs
US20120088734A1 (en)	2010-10-12	2012-04-12	Allergan, Inc.	Cyclosporin Analogs
PL2651965T3 (pl)	2010-12-15	2019-04-30	Contravir Pharmaceuticals Inc	Cząsteczki analogów cyklosporyny modyfikowane w aminokwasach 1 i 3
DE102011111991A1 (de) *	2011-08-30	2013-02-28	Lead Discovery Center Gmbh	Neue Cyclosporin-Derivate
EP2705856A1 (en)	2012-09-07	2014-03-12	Deutsches Zentrum für Neurodegenerative Erkrankungen e.V.	Compounds for the treatment of neurodegenerative disorders
CN104603146B (zh)	2012-09-29	2018-01-02	诺华股份有限公司	环肽类化合物及其作为药物的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0194972B1 (en) *	1985-03-11	1992-07-29	Sandoz Ag	Novel cyclosporins
US4814323A (en) *	1986-03-25	1989-03-21	Andrieu J M	Process for the treatment and the prevention of AIDS and other disorders induced by the LAV/HTLV III virus
US4798823A (en) *	1987-06-03	1989-01-17	Merck & Co., Inc.	New cyclosporin analogs with modified "C-9 amino acids"
US4885276A (en) *	1987-06-03	1989-12-05	Merck & Co., Inc.	Cyclosporin analogs with modified "C-9 amino acids"
DK0484281T4 (da) *	1990-11-02	2001-02-05	Novartis Ag	Cyclosporiner
US5512555A (en) *	1994-07-21	1996-04-30	Merck & Co., Inc.	Method of treating sweat-related conditions using finasteride, epristeride and a cholestan-3-one
CN1141317C (zh) *	1995-07-17	2004-03-10	碳化学公司	有抗人体免疫缺损病毒作用的环孢菌素衍生物

1997
- 1997-04-30 FR FR9705351A patent/FR2762843B1/fr not_active Expired - Fee Related
1998
- 1998-04-27 AU AU75357/98A patent/AU7535798A/en not_active Abandoned
- 1998-04-27 JP JP54666498A patent/JP2001524105A/ja active Pending
- 1998-04-27 EP EP98922872A patent/EP0979244B1/fr not_active Expired - Lifetime
- 1998-04-27 WO PCT/FR1998/000838 patent/WO1998049193A1/fr active IP Right Grant
- 1998-04-27 ES ES98922872T patent/ES2236902T3/es not_active Expired - Lifetime
- 1998-04-27 AT AT98922872T patent/ATE290015T1/de active
- 1998-04-27 DE DE69829175T patent/DE69829175T2/de not_active Expired - Lifetime
- 1998-04-27 PT PT98922872T patent/PT979244E/pt unknown
- 1998-04-27 MA MA25048A patent/MA26488A1/fr unknown
- 1998-04-29 TN TNTNSN98057A patent/TNSN98057A1/fr unknown
- 1998-04-29 ZA ZA983618A patent/ZA983618B/xx unknown
- 1998-04-30 US US09/069,959 patent/US5977067A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69829175D1 (de)	2005-04-07
FR2762843B1 (fr)	1999-12-10
MA26488A1 (fr)	2004-12-20
EP0979244A1 (fr)	2000-02-16
US5977067A (en)	1999-11-02
WO1998049193A1 (fr)	1998-11-05
DE69829175T2 (de)	2006-02-16
ES2236902T3 (es)	2005-07-16
AU7535798A (en)	1998-11-24
FR2762843A1 (fr)	1998-11-06
JP2001524105A (ja)	2001-11-27
EP0979244B1 (fr)	2005-03-02
ZA983618B (en)	1998-11-04
TNSN98057A1 (fr)	2005-03-15
ATE290015T1 (de)	2005-03-15

Publication	Publication Date	Title
PT979244E (pt)	2005-06-30	Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem
PT948527E (pt)	2002-11-29	Novos derivados de ciclosporina sua preparacao e composicoes farmaceuticas que os contem
PT951474E (pt)	2002-11-29	Novos derivados da ciclosporina sua preparacao e composicoes farmaceuticas que os contem
TR200200579T2 (tr)	2002-12-23	Amino-tirazolpiridin türevleri.
BR0215240A (pt)	2004-10-26	Derivados de calcona e seu uso no tratamento de doenças
SE9504661D0 (sv)	1995-12-22	New compounds
KR0141913B1 (en)	1998-06-01	Anti-virus agents
ATE108437T1 (de)	1994-07-15	Substituierte diaminophthalimide und analoga.
FI972434A (fi)	1997-06-09	Lamotrigiiniä sisältävä farmaseuttinen koostumus
MD1560F2 (en)	2000-11-30	Cyclic compounds, pharmaceutical compositions on base thereof and methods of treatment of infections or diseases provoked by retroviruses.
DK0387821T3 (da)	1994-09-19	2-Alkyl-4-arylmethylchinoliner, deres anvendelse og lægemidler fremstillet hermed
PH27446A (en)	1993-07-02	Compound with gastric acid inhibitory effect
SE9504662D0 (sv)	1995-12-22	New compounds
MY121604A (en)	2006-02-28	Combination therapy for hiv infection using the hiv protease inhibitor indinavir and the reverse transcriptase inhibitor 3tc together with azt
BR0011845A (pt)	2002-03-05	Complexo farmacêutico
EP1411956B8 (en)	2005-10-05	Use of oversulfated polysaccharides as inhibitors of hiv
IL112110A0 (en)	1995-03-15	Octahydro-1h-isoindoles and pharmaceutical compositions containing them
BR0213463A (pt)	2004-11-09	Composições farmacêuticas contendo macrólidos
KR960700053A (ko)	1996-01-19	방사선회복제로서 리루졸의 이용(application of riluzole as a radiorestorer)