PT97905A - Processo para a preparacao de composicoes farmaceuticas contendo derivados da cistina - Google Patents

Processo para a preparacao de composicoes farmaceuticas contendo derivados da cistina

Info

Publication number: PT97905A
Authority: PT; Portugal
Prior art keywords: cistine; derivatives; pharmaceutical compositions; compositions containing; preparing pharmaceutical
Prior art date: 1990-06-08

Application number

PT97905A

Other languages

English (en)

Other versions

PT97905B (pt

Inventor

Carl-Magnus Alexande Andersson

Sten Hakan Axel Bergstrand

Anders Rudolf Hallberg

Bengt Olof Sarnstrand

Per Anders Sigvard Tunek

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-08

Filing date

1991-06-07

Publication date

1992-03-31

1990-06-08 Priority claimed from SE9002067A external-priority patent/SE9002067D0/xx

1990-06-28 Priority claimed from SE9002275A external-priority patent/SE9002275D0/xx

1991-06-07 Application filed by Astra Ab filed Critical Astra Ab

1992-03-31 Publication of PT97905A publication Critical patent/PT97905A/pt

1998-10-30 Publication of PT97905B publication Critical patent/PT97905B/pt

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
239000004480 active ingredient Substances 0.000 abstract 1
LEVWYRKDKASIDU-IMJSIDKUSA-N cystine group Chemical class C([C@@H](C(=O)O)N)SSC[C@@H](C(=O)O)N LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 abstract 1
210000000987 immune system Anatomy 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
230000000638 stimulation Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Immunology (AREA)
Emergency Medicine (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Obesity (AREA)
Hematology (AREA)
Virology (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Communicable Diseases (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Oncology (AREA)
AIDS & HIV (AREA)
Pain & Pain Management (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Heart & Thoracic Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Otolaryngology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PT97905A 1990-06-08 1991-06-07 Processo para a preparacao de composicoes farmaceuticas contendo derivados da cistina PT97905B (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9002067A SE9002067D0 (sv)	1990-06-08	1990-06-08	The pharmacological use of certain cystine derivatives
SE9002275A SE9002275D0 (sv)	1990-06-28	1990-06-28	Novel 3,3'-dithiobis(propionic acids)

Publications (2)

Publication Number	Publication Date
PT97905A true PT97905A (pt)	1992-03-31
PT97905B PT97905B (pt)	1998-10-30

Family

ID=26660796

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97905A PT97905B (pt)	1990-06-08	1991-06-07	Processo para a preparacao de composicoes farmaceuticas contendo derivados da cistina

Country Status (20)

Country	Link
US (2)	US5441976A (pt)
EP (1)	EP0532595B1 (pt)
JP (1)	JP3204320B2 (pt)
KR (1)	KR100236253B1 (pt)
AT (1)	ATE144705T1 (pt)
AU (1)	AU652946B2 (pt)
CA (1)	CA2083274C (pt)
DE (1)	DE69122961T2 (pt)
DK (1)	DK0532595T3 (pt)
HK (1)	HK62597A (pt)
HU (1)	HU215920B (pt)
IE (1)	IE80754B1 (pt)
IL (1)	IL98310A (pt)
LV (2)	LV10186B (pt)
NO (1)	NO924723D0 (pt)
NZ (1)	NZ247658A (pt)
PT (1)	PT97905B (pt)
RU (1)	RU2119793C1 (pt)
SG (1)	SG49736A1 (pt)
WO (1)	WO1991018594A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9018994D0 (en) *	1990-08-31	1990-10-17	Secr Defence	Toxic agent protective compounds
US5889050A (en) *	1991-06-21	1999-03-30	Astra Aktiebolag	3,3'-dithiobis (propionic acids) and esters thereof
SE9103572D0 (sv) *	1991-11-29	1991-11-29	Astra Ab	Organic salts of n,n'-diacetyl cystine
JP2947044B2 (ja) *	1993-01-27	1999-09-13	味の素株式会社	免疫不全症候群治療の補助療法剤
DE4329857C2 (de) *	1993-09-03	1995-08-24	Deutsches Krebsforsch	Verbindung zur Stärkung des Immunsystems und von Immunreaktionen
SE9500897D0 (sv) *	1995-03-14	1995-03-14	Astra Ab	The pharmacological use of certain cystine derivatives
SE9501067D0 (sv) *	1995-03-24	1995-03-24	Astra Ab	New peptides
SE9602262D0 (sv) *	1996-06-06	1996-06-06	Astra Ab	New use of derivatives of cystine
US20030203006A1 (en) *	1997-10-29	2003-10-30	Ajinomoto Co. Inc.	Immunomodulator
US6197749B1 (en)	1997-10-29	2001-03-06	Ajinomoto Co., Inc.	Method of suppressing immune responses by reducing intracellular content of glutathione in macrophages and monocytes
EP1120407B1 (en)	1998-10-09	2013-02-20	Ajinomoto Co., Inc.	Cystine derivatives
EP1004302A3 (en) *	1998-10-29	2003-06-04	Ajinomoto Co., Inc.	Immunomodulator
SE9900438D0 (sv) *	1999-02-10	1999-02-10	Astra Ab	The pharmacological use of certian cystine derivatives
JP3988014B2 (ja) *	2000-02-02	2007-10-10	味の素株式会社	ウイルス感染症予防剤
PT2283817T (pt)	2000-11-30	2016-08-22	Vectura Ltd	Método de fabrico de partículas para utilização numa composição farmacêutica
SE518784C2 (sv) *	2000-12-27	2002-11-19	Nactilus Ab	"N-Acetyl-L-cystein med kompositioner för behandling av neoplasier"
US8530509B2 (en)	2003-06-20	2013-09-10	Siga Technologies, Inc.	Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases
DE102004043055B4 (de)	2004-09-06	2009-04-02	Siemens Ag	Führungsvorrichtung zur Führung eines bewegbaren Maschinenelementes einer Maschine
WO2008066603A2 (en) *	2006-10-03	2008-06-05	Galleon Pharmaceuticals, Inc.	S-nitrosothiol compounds and related derivatives
MX348481B (es) *	2007-04-23	2017-06-15	Siga Tech Inc	Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.
US7829709B1 (en)	2007-08-10	2010-11-09	Marquette University	Cysteine prodrugs to treat schizophrenia and drug addiction
JP5796881B2 (ja) *	2008-02-07	2015-10-21	マーケットユニバーシティー	統合失調症を治療するため及び薬物渇望を低減するためのシステイン及びシスチンプロドラッグ
JP6458809B2 (ja)	2014-04-25	2019-01-30	味の素株式会社	免疫賦活剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR8205M (pt) *	1968-12-20	1970-09-14
US3878305A (en) *	1972-05-25	1975-04-15	Procter & Gamble	Fortification of foodstuffs with n-acyl derivatives of sulphur-containing l-amino acids
US3952115A (en) *	1975-04-02	1976-04-20	The Procter & Gamble Company	Fortification of foodstuffs with N-acyl derivatives of sulfur-containing L-amino acid esters
FR2503151A1 (fr) *	1981-04-02	1982-10-08	Morelle Jean	Butyryminoacides soufres. mode de preparation. emploi comme element keratogenique chez l'homme et l'animal et comme agent de fertilisation chez les vegetaux
GB2097256B (en) *	1981-04-02	1985-05-30	Morelle Jean V	Compositions containing n-butyryl alphaaminoacids
US4827016A (en) *	1985-09-16	1989-05-02	Morgan Lee R	Method and compounds for reducing dermal inflammations
US4724239A (en) *	1985-09-16	1988-02-09	Morgan Lee R	Method of treating chemical ulcers with N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine
US4708965A (en) *	1985-09-16	1987-11-24	Morgan Lee R	Method of treating herpes virus infections with N,N'-diacetylcystine and derivatives
IT1249650B (it) *	1991-05-29	1995-03-09	Poli Ind Chimica Spa	N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico

1991
- 1991-05-30 IL IL9831091A patent/IL98310A/en not_active IP Right Cessation
- 1991-06-03 KR KR1019920703125A patent/KR100236253B1/ko not_active IP Right Cessation
- 1991-06-03 EP EP91910813A patent/EP0532595B1/en not_active Expired - Lifetime
- 1991-06-03 AU AU80941/91A patent/AU652946B2/en not_active Ceased
- 1991-06-03 SG SG1996004501A patent/SG49736A1/en unknown
- 1991-06-03 RU RU92016463A patent/RU2119793C1/ru not_active IP Right Cessation
- 1991-06-03 WO PCT/SE1991/000388 patent/WO1991018594A1/en active IP Right Grant
- 1991-06-03 DE DE69122961T patent/DE69122961T2/de not_active Expired - Fee Related
- 1991-06-03 HU HU9203871A patent/HU215920B/hu not_active IP Right Cessation
- 1991-06-03 JP JP51096391A patent/JP3204320B2/ja not_active Expired - Fee Related
- 1991-06-03 AT AT91910813T patent/ATE144705T1/de not_active IP Right Cessation
- 1991-06-03 CA CA002083274A patent/CA2083274C/en not_active Expired - Fee Related
- 1991-06-03 DK DK91910813.4T patent/DK0532595T3/da active
- 1991-06-07 IE IE194591A patent/IE80754B1/en not_active IP Right Cessation
- 1991-06-07 PT PT97905A patent/PT97905B/pt not_active IP Right Cessation
1992
- 1992-12-04 US US07/949,648 patent/US5441976A/en not_active Expired - Lifetime
- 1992-12-07 NO NO924723A patent/NO924723D0/no unknown
1993
- 1993-05-20 NZ NZ247658A patent/NZ247658A/en unknown
- 1993-08-06 LV LVP-93-1017A patent/LV10186B/en unknown
1995
- 1995-06-01 US US08/457,004 patent/US5780508A/en not_active Expired - Fee Related
1997
- 1997-05-08 HK HK62597A patent/HK62597A/xx not_active IP Right Cessation
- 1997-10-30 LV LVP-97-219A patent/LV11985B/en unknown

Also Published As

Publication number	Publication date
CA2083274A1 (en)	1991-12-09
LV11985B (en)	1998-06-20
IE80754B1 (en)	1999-01-13
NO924723L (no)	1992-12-07
EP0532595A1 (en)	1993-03-24
CA2083274C (en)	2002-05-28
DE69122961T2 (de)	1997-03-13
LV10186A (lv)	1994-10-20
WO1991018594A1 (en)	1991-12-12
AU8094191A (en)	1991-12-31
AU652946B2 (en)	1994-09-15
RU2119793C1 (ru)	1998-10-10
HU9203871D0 (en)	1993-03-29
NO924723D0 (no)	1992-12-07
US5441976A (en)	1995-08-15
SG49736A1 (en)	1998-06-15
PT97905B (pt)	1998-10-30
LV11985A (lv)	1998-03-20
JPH05507705A (ja)	1993-11-04
IL98310A (en)	1996-08-04
IE911945A1 (en)	1991-12-18
DK0532595T3 (da)	1997-04-07
HK62597A (en)	1997-05-16
LV10186B (en)	1995-08-20
US5780508A (en)	1998-07-14
HUT70055A (en)	1995-09-28
DE69122961D1 (de)	1996-12-05
NZ247658A (en)	2000-07-28
JP3204320B2 (ja)	2001-09-04
EP0532595B1 (en)	1996-10-30
HU215920B (hu)	1999-03-29
IL98310A0 (en)	1992-06-21
KR100236253B1 (ko)	1999-12-15
ATE144705T1 (de)	1996-11-15

Legal Events

Date

Code

Title

Description

1992-03-31

BB1A

Laying open of patent application

Effective date: 19911118

1998-10-30

FG3A

Patent granted, date of granting

Effective date: 19980723

2005-03-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20050124

Publication	Publication Date	Title
PT97905A (pt)	1992-03-31	Processo para a preparacao de composicoes farmaceuticas contendo derivados da cistina
MA22842A1 (fr)	1993-10-01	Procede de preparation de compositions de vaccin.
DE69620877T2 (de)	2002-12-12	Arzneimittelformulierungen für il-12
MX9100990A (es)	1992-05-04	Compuesto monohidrato de furoato de mometasona,al procedimiento para su preparacion y a las composiciones farmaceuticas
MX9202544A (es)	1992-11-01	Compuestos de diaminoftalimidas substituidas y analogas, procedimiento para su preparacion y preparados farmaceuticos que los contienen.
ES2108772T3 (es)	1998-01-01	Derivados de aminofosfonato substituidos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
MX9304793A (es)	1994-05-31	Glicanas de actividad inmunoestimulante.
DK0789590T3 (da)	2002-11-04	Chitosaninduceret immunforstærkning
GR1001597B (el)	1994-06-30	Νέα βιολογικώς δραστικά παράγωγα εμπουρναμενίνης, φαρμακευτικές συν?έσεις οι οποίες περιέχουν αυτά και μέ?οδος δια την παρασκευή αυτών.
GR3017107T3 (en)	1995-11-30	Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them.
DK561089A (da)	1990-05-11	Anvendelse af lactamimider til fremstilling af laegemidler
GR1000467B (el)	1992-07-30	Μεθοδος παρασκευης τρικυκλικων παραγωγων 3-οξο-προπανονιτριλιου.
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