PT923934E - Formulacao de matriz de libertacao modificada de cefaclor e cefalexina - Google Patents
Formulacao de matriz de libertacao modificada de cefaclor e cefalexinaInfo
- Publication number
- PT923934E PT923934E PT98302445T PT98302445T PT923934E PT 923934 E PT923934 E PT 923934E PT 98302445 T PT98302445 T PT 98302445T PT 98302445 T PT98302445 T PT 98302445T PT 923934 E PT923934 E PT 923934E
- Authority
- PT
- Portugal
- Prior art keywords
- hydrophilic polymers
- cefaclor
- active ingredient
- weight
- water soluble
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/992,151 US5948440A (en) | 1997-12-17 | 1997-12-17 | Modified release matrix formulation of cefaclor and cephalexin |
Publications (1)
Publication Number | Publication Date |
---|---|
PT923934E true PT923934E (pt) | 2003-12-31 |
Family
ID=25537971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98302445T PT923934E (pt) | 1997-12-17 | 1998-03-30 | Formulacao de matriz de libertacao modificada de cefaclor e cefalexina |
Country Status (9)
Country | Link |
---|---|
US (1) | US5948440A (es) |
EP (1) | EP0923934B1 (es) |
AT (1) | ATE246505T1 (es) |
AU (1) | AU741361B2 (es) |
DE (1) | DE69816951T2 (es) |
DK (1) | DK0923934T3 (es) |
ES (1) | ES2203885T3 (es) |
NZ (1) | NZ329679A (es) |
PT (1) | PT923934E (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19845358A1 (de) * | 1998-10-02 | 2000-04-06 | Roehm Gmbh | Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe |
IE990406A1 (en) * | 1999-05-20 | 2000-12-27 | Elan Corp Plc | Multiparticulate controlled release selective serotonin reuptake inhibitor formulations. |
KR100647901B1 (ko) * | 1999-07-09 | 2006-11-17 | 보령제약 주식회사 | 세파클러-함유 서방성 약제조성물 및 그의 제조방법 |
US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
IT1318495B1 (it) * | 2000-05-04 | 2003-08-25 | Lisapharma Spa | Formulazioni farmaceutiche, a rilascio modificato, con elevatabiodisponibilita', contenenti principi attivi ad attivita' |
BR0114272A (pt) | 2000-09-29 | 2003-08-26 | Solvay Pharm Bv | Formulação farmacêutica de liberação prolongada independente da força iÈnica |
US20020068078A1 (en) | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
AU2002224011B2 (en) * | 2001-11-19 | 2008-05-01 | Lupin Limited | A pharmaceutical composition for controlled release of a beta-lactam antibiotic |
US20040033262A1 (en) * | 2002-08-19 | 2004-02-19 | Orchid Health Care | Sustained release pharmaceutical composition of a cephalosporin antibiotic |
AU2003255874A1 (en) * | 2002-08-16 | 2004-03-03 | Orchid Health Care, A Division Of Orchid Chemicals And Pharmaceuticals Ltd. | Sustained release pharmaceutical composition of a cephalosporin antibiotic |
US9060941B2 (en) * | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
US7959946B2 (en) | 2002-09-20 | 2011-06-14 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
US7785627B2 (en) | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
US8084058B2 (en) * | 2002-09-20 | 2011-12-27 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
US20050025825A1 (en) | 2003-07-31 | 2005-02-03 | Xanodyne Pharmacal, Inc. | Tranexamic acid formulations with reduced adverse effects |
EP1667661A1 (en) * | 2003-09-30 | 2006-06-14 | Lupin Limited | Extended release formulation of beta-lactam antibiotics |
CA2543324C (en) * | 2003-10-24 | 2011-02-01 | Adhesives Research, Inc. | Rapidly disintegrating films for delivery of pharmaceutical or cosmetic agents |
US20050244495A1 (en) | 2004-03-04 | 2005-11-03 | Xanodyne Pharmaceuticals, Inc. | Tranexamic acid formulations |
US7947739B2 (en) | 2004-03-04 | 2011-05-24 | Ferring B.V. | Tranexamic acid formulations |
US20090215898A1 (en) | 2004-03-04 | 2009-08-27 | Xanodyne Pharmaceuticals, Inc. | Tranexamic acid formulations |
US8022106B2 (en) | 2004-03-04 | 2011-09-20 | Ferring B.V. | Tranexamic acid formulations |
DE102004023069A1 (de) * | 2004-05-11 | 2005-12-08 | Bayer Healthcare Ag | Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil |
US8604222B2 (en) | 2004-07-30 | 2013-12-10 | Forest Laboratories Holdings Limited | Nebivolol and its pharmaceutically acceptable salts, process for preparation and pharmaceutical compositions of nebivolol |
NZ554525A (en) * | 2004-09-30 | 2010-12-24 | Hershey Co | Sealed, edible film strip packets and methods of making and using them |
KR101082774B1 (ko) | 2006-04-12 | 2011-11-11 | 닛뽕소다 가부시키가이샤 | 서방성 정제의 제조 방법 |
PT103884A (pt) * | 2006-11-17 | 2008-05-19 | Astrazeneca Ab | Composições de libertação prolongada e métodos para a sua preparação |
LT2395840T (lt) | 2009-02-13 | 2020-07-10 | Romark Laboratories, L.C. | Nitazoksanido kontroliuojamo atpalaidavimo farmacinės kompozicijos |
FR2962550B1 (fr) * | 2010-07-06 | 2013-06-14 | Ethypharm Sa | Methode pour lutter contre la soumission chimique, utilisation d'agent colorant pour lutter contre la soumission chimique et composition pharmaceutique permettant la mise en oeuvre de la methode |
CN101912373B (zh) * | 2010-08-24 | 2012-01-04 | 北京京丰制药有限公司 | 稳定的头孢克洛分散片及其制备方法 |
CN112137984B (zh) * | 2020-10-30 | 2023-02-03 | 四川制药制剂有限公司 | 头孢克洛胶囊及其制备工艺 |
CN113750066B (zh) * | 2021-10-12 | 2022-12-02 | 上海金城素智药业有限公司 | 一种具有临床优势的头孢克洛制剂及其制备方法和应用 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3065143A (en) * | 1960-04-19 | 1962-11-20 | Richardson Merrell Inc | Sustained release tablet |
US4250166A (en) * | 1977-05-27 | 1981-02-10 | Shionogi & Co., Ltd. | Long acting preparation of cefalexin for effective treatments of bacterial infection sensitive to cefalexin |
FR2470599A1 (fr) * | 1979-12-07 | 1981-06-12 | Panoz Donald | Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus |
US4259314A (en) * | 1979-12-10 | 1981-03-31 | Hans Lowey | Method and composition for the preparation of controlled long-acting pharmaceuticals |
JPS6024765B2 (ja) * | 1981-11-27 | 1985-06-14 | 辰巳化学株式会社 | セフアレキシンの持続性製剤の製造方法 |
US4369172A (en) * | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
US4557925A (en) * | 1982-07-08 | 1985-12-10 | Ab Ferrosan | Membrane-coated sustained-release tablets and method |
JPS601128A (ja) * | 1983-06-15 | 1985-01-07 | Shionogi & Co Ltd | 作用持続型セフアクロル製剤 |
US4795327A (en) * | 1984-03-26 | 1989-01-03 | Forest Laboratories, Inc. | Controlled release solid drug dosage forms based on mixtures of water soluble nonionic cellulose ethers and anionic surfactants |
JPS6124516A (ja) * | 1984-07-12 | 1986-02-03 | Fujisawa Pharmaceut Co Ltd | 持続性錠剤 |
US4734285A (en) * | 1985-10-28 | 1988-03-29 | The Dow Chemical Company | Sustained release compositions |
US4704285A (en) * | 1985-11-18 | 1987-11-03 | The Dow Chemical Company | Sustained release compositions comprising hydroxypropyl cellulose ethers |
DE3607946A1 (de) * | 1986-03-11 | 1987-09-17 | Basf Ag | Verfahren zur einengung der molekulargewichtsverteilung von polytetrahydrofuran und von copolymerisaten aus tetrahydrofuran und alkylenoxiden |
US4756911A (en) * | 1986-04-16 | 1988-07-12 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
GB8616669D0 (en) * | 1986-07-09 | 1986-08-13 | Merk Sharpe & Dohme Ltd | Pharmaceutical compositions |
US4968508A (en) * | 1987-02-27 | 1990-11-06 | Eli Lilly And Company | Sustained release matrix |
US4786503A (en) * | 1987-04-06 | 1988-11-22 | Alza Corporation | Dosage form comprising parallel lamine |
AU609234B2 (en) * | 1987-12-21 | 1991-04-26 | Forest Laboratories, Inc. | Sustained release drug dosage forms containing hydroxypropylmethylcellulose and alkali metal carboxylates |
US4983398A (en) * | 1987-12-21 | 1991-01-08 | Forest Laboratories, Inc. | Sustained release drug dosage forms containing hydroxypropylmethylcellulose and alkali metal carboxylates |
BR9707780A (pt) * | 1996-02-29 | 1999-07-27 | Fujisawa Pharmaceutical Co | Comprimido contendo antibíotico de b-lactama e método para produzir comprimidos contendo antibíotico de b-lactama |
-
1997
- 1997-12-17 US US08/992,151 patent/US5948440A/en not_active Expired - Fee Related
-
1998
- 1998-01-28 NZ NZ329679A patent/NZ329679A/en unknown
- 1998-02-03 AU AU52906/98A patent/AU741361B2/en not_active Ceased
- 1998-03-30 PT PT98302445T patent/PT923934E/pt unknown
- 1998-03-30 ES ES98302445T patent/ES2203885T3/es not_active Expired - Lifetime
- 1998-03-30 DE DE69816951T patent/DE69816951T2/de not_active Expired - Fee Related
- 1998-03-30 EP EP98302445A patent/EP0923934B1/en not_active Expired - Lifetime
- 1998-03-30 DK DK98302445T patent/DK0923934T3/da active
- 1998-03-30 AT AT98302445T patent/ATE246505T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0923934A1 (en) | 1999-06-23 |
ATE246505T1 (de) | 2003-08-15 |
AU5290698A (en) | 1999-07-08 |
ES2203885T3 (es) | 2004-04-16 |
US5948440A (en) | 1999-09-07 |
NZ329679A (en) | 1999-10-28 |
DE69816951D1 (de) | 2003-09-11 |
AU741361B2 (en) | 2001-11-29 |
DK0923934T3 (da) | 2003-11-24 |
EP0923934B1 (en) | 2003-08-06 |
DE69816951T2 (de) | 2004-06-17 |
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