PT915841E - Derivados anilinopeptidos - Google Patents

Derivados anilinopeptidos

Info

Publication number
PT915841E
PT915841E PT97934472T PT97934472T PT915841E PT 915841 E PT915841 E PT 915841E PT 97934472 T PT97934472 T PT 97934472T PT 97934472 T PT97934472 T PT 97934472T PT 915841 E PT915841 E PT 915841E
Authority
PT
Portugal
Prior art keywords
lower alkyl
independently
triazol
salt
compounds
Prior art date
Application number
PT97934472T
Other languages
English (en)
Inventor
Hans-Georg Capraro
Guido Bold
Alexander Fassler
Marc Lang
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT915841E publication Critical patent/PT915841E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
PT97934472T 1996-07-17 1997-07-16 Derivados anilinopeptidos PT915841E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH178896 1996-07-17

Publications (1)

Publication Number Publication Date
PT915841E true PT915841E (pt) 2002-08-30

Family

ID=4218620

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97934472T PT915841E (pt) 1996-07-17 1997-07-16 Derivados anilinopeptidos

Country Status (10)

Country Link
US (1) US6451973B1 (pt)
EP (1) EP0915841B1 (pt)
JP (1) JP4100710B2 (pt)
AT (1) ATE213725T1 (pt)
AU (1) AU3767797A (pt)
DE (1) DE69710731T2 (pt)
DK (1) DK0915841T3 (pt)
ES (1) ES2173466T3 (pt)
PT (1) PT915841E (pt)
WO (1) WO1998003476A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4100710B2 (ja) * 1996-07-17 2008-06-11 ノバルティス アクチエンゲゼルシャフト アニリノペプチド誘導体
RU2004117082A (ru) 2001-12-05 2005-04-10 Орто-Макнейл Фармасьютикал, Инк. (Us) Кетолидные 6-0-ацил-производные эритромицина в качестве антибактериальных средств
WO2005061487A1 (en) * 2003-12-11 2005-07-07 Abbott Laboratories Hiv protease inhibiting compounds
ATE539074T1 (de) * 2003-12-11 2012-01-15 Abbott Lab Die hiv-protease hemmende verbindungen
PT2069303E (pt) 2006-07-21 2016-06-08 Gilead Sciences Inc Inibidores de protease antiviral
WO2011080562A1 (en) 2009-12-29 2011-07-07 Hetero Research Foundation Novel aza-peptides containing 2,2-disubstituted cyclobutyl and/or substituted alkoxy benzyl derivatives as antivirals
JOP20180009A1 (ar) 2017-02-06 2019-01-30 Gilead Sciences Inc مركبات مثبط فيروس hiv
TWI766172B (zh) 2018-07-30 2022-06-01 美商基利科學股份有限公司 抗hiv化合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556654A (en) 1983-06-28 1985-12-03 Warner-Lambert Company Antimicrobial substituted anthra[1,9-cd]pyrazol-6(2H)-ones
IE20010533A1 (en) 1990-11-20 2003-03-05 Abbott Lab Intermediates for preparing retroviral protease inhibiting compounds
US5753652A (en) * 1991-07-03 1998-05-19 Novartis Corporation Antiretroviral hydrazine derivatives
WO1993018006A1 (en) 1992-03-11 1993-09-16 Narhex Limited Amine derivatives of oxo- and hydroxy-substitued hydrocarbons
DE59303870D1 (de) 1992-12-23 1996-10-24 Ciba Geigy Ag Antiretrovirale hydrazinderivate
KR100360964B1 (ko) 1992-12-29 2002-11-22 아보트 러보러터리즈 레트로바이러스성 프로테아제 억제 화합물의 중간체의제조방법
US5461067A (en) 1993-02-25 1995-10-24 Abbott Laboratories Retroviral protease inhibiting compounds
EP0708085B1 (en) 1994-10-19 2002-07-17 Novartis AG Antiviral ethers of aspartate protease substrate isosteres
US5849911A (en) * 1996-04-22 1998-12-15 Novartis Finance Corporation Antivirally active heterocyclic azahexane derivatives
JP4100710B2 (ja) * 1996-07-17 2008-06-11 ノバルティス アクチエンゲゼルシャフト アニリノペプチド誘導体

Also Published As

Publication number Publication date
JP4100710B2 (ja) 2008-06-11
EP0915841B1 (en) 2002-02-27
AU3767797A (en) 1998-02-10
DE69710731D1 (de) 2002-04-04
ATE213725T1 (de) 2002-03-15
DK0915841T3 (da) 2002-06-10
EP0915841A1 (en) 1999-05-19
DE69710731T2 (de) 2002-10-24
WO1998003476A1 (en) 1998-01-29
US6451973B1 (en) 2002-09-17
ES2173466T3 (es) 2002-10-16
JP2000515147A (ja) 2000-11-14

Similar Documents

Publication Publication Date Title
DE69402173T2 (de) Hemmung von Thrombin
DK0558673T3 (da) Retrovirale proteaseinhibitorer
FI942252A (fi) Piperatsiinijohdannaisia
DE69420564D1 (de) Immunsuppressive und antiallergische verbindungen; z.b. n-(3-oxohexanoyl)-homoserinlacton
UA26930C2 (uk) Засіб для іhгібуваhhя еhдометріозу
DK0554400T3 (da) Retrovirale proteaseinhibitorer
MX9701325A (es) Metodos para inhibir la mucositis ulcerativa.
DE69402165T2 (de) Hemmung von Seborrhoe und Akne
DE69433578D1 (de) Hemmung der Endprodukte fortgeschrittener Glykolisierung
NO943874D0 (no) Behandling av resistant neoplasma
ATE213725T1 (de) Anilinopeptid-derivate
UA26459C2 (uk) Іhгібітор впливу амілоїдhих білків
ATE203406T1 (de) Hemmung von hirsutismus und alopecia bei frauen
NO942668L (no) Alkylderivater av trazodon med CNS-aktivitet