PT90321A - Processo para a preparacao de polipeptideos de veneno de vibora - Google Patents

Processo para a preparacao de polipeptideos de veneno de vibora

Info

Publication number: PT90321A
Authority: PT; Portugal
Prior art keywords: amino acid; polipeptidees; viene; vibe; preparation
Prior art date: 1988-04-22

Application number

PT90321A

Other languages

English (en)

Other versions

PT90321B (pt

Inventor

John A Friedman

John W Jacobs

Mark A Polokoff

Robert J Gould

Gerard H Bencen

Victor M Garsky

Zhong-Ru Gan

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-04-22

Filing date

1989-04-20

Publication date

1989-11-10

1989-04-20 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1989-11-10 Publication of PT90321A publication Critical patent/PT90321A/pt

1994-08-31 Publication of PT90321B publication Critical patent/PT90321B/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Hematology (AREA)
Zoology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PT90321A 1988-04-22 1989-04-20 Processo para a preparacao de polipeptideos de veneno de vibora PT90321B (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US18464988A	1988-04-22	1988-04-22
US18465388A	1988-04-22	1988-04-22
US30375789A	1989-02-01	1989-02-01

Publications (2)

Publication Number	Publication Date
PT90321A true PT90321A (pt)	1989-11-10
PT90321B PT90321B (pt)	1994-08-31

Family

ID=27391870

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT90321A PT90321B (pt)	1988-04-22	1989-04-20	Processo para a preparacao de polipeptideos de veneno de vibora

Country Status (14)

Country	Link
EP (1)	EP0338634B1 (pt)
JP (1)	JPH02138298A (pt)
KR (1)	KR900016261A (pt)
CN (1)	CN1039441A (pt)
AT (1)	ATE103931T1 (pt)
AU (1)	AU627724B2 (pt)
DE (1)	DE68914316T2 (pt)
DK (1)	DK192189A (pt)
ES (1)	ES2063113T3 (pt)
FI (1)	FI891916A (pt)
IL (1)	IL89938A0 (pt)
NO (1)	NO891662L (pt)
NZ (1)	NZ228710A (pt)
PT (1)	PT90321B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5827821A (en) *	1987-12-10	1998-10-27	The Burnham Institute	Conformationally stabilized cell adhesion peptides
WO1989005150A1 (en) *	1987-12-10	1989-06-15	La Jolla Cancer Research Foundation	Conformationally stabilized cell adhesion peptides
US5196403A (en) *	1989-01-27	1993-03-23	Biogen, Inc.	Method of inhibiting platelet activation
US5182260A (en) *	1989-01-27	1993-01-26	Biogen, Inc.	Dna sequences encoding snake venom inhibitors of platelet activation processes for producing those inhibitors and compositions using them
EP0382451A3 (en) *	1989-02-07	1991-05-29	Merck & Co. Inc.	Viper venom polypeptides and variants
EP0382538A3 (en) *	1989-02-09	1991-10-23	Merck & Co. Inc.	A process for the preparation of cysteine-rich polypeptides, including echistatin
US5384309A (en) *	1989-07-17	1995-01-24	Genentech, Inc.	Cyclized peptides and their use as platelet aggregation inhibitors
WO1991011458A1 (en) *	1990-02-02	1991-08-08	Genentech, Inc.	CYCLIC PEPTIDES CONTAINING Arg-Gly-Asp FLANKED BY PROLINE
US5227469A (en) *	1990-02-14	1993-07-13	Genentech, Inc.	Platelet aggregation inhibitors from the leech
US5612311A (en) *	1990-04-06	1997-03-18	La Jolla Cancer Research Foundation	Method and composition for treating thrombosis
US5780303A (en) *	1990-04-06	1998-07-14	La Jolla Cancer Research Foundation	Method and composition for treating thrombosis
AU660926B2 (en) *	1990-04-06	1995-07-13	La Jolla Cancer Research Foundation	Method and composition for treating thrombosis
US5648330A (en) *	1990-04-06	1997-07-15	La Jolla Cancer Research Foundation	Method and composition for treating vascular graft occlusion
US6521594B1 (en)	1990-04-06	2003-02-18	La Jolla Cancer Research Foundation	Method and composition for treating thrombosis
US5179082A (en) *	1990-11-13	1993-01-12	Merck & Co., Inc.	Method for blocking platelet adhesion to collagen
US5342830A (en) *	1990-11-16	1994-08-30	Cor Therapeutics, Inc.	Antithrombosis agents
US5242810A (en) *	1990-12-07	1993-09-07	Biogen, Inc.	Bifunctional inhibitors of thrombin and platelet activation
JPH06509551A (ja) *	1991-04-05	1994-10-27	ジェネンテク，インコーポレイテッド	Ｇｐ　ＩＩ↓ｂＩＩＩ↓ａに対する高い特異性を有する血小板凝集阻害剤
US5380646A (en) *	1992-10-19	1995-01-10	Temple University Of The Commonwealth System Of Higher Education	Thrombus detection using radiolabelled disintegrins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4683291A (en) *	1985-10-28	1987-07-28	Scripps Clinic And Research Foundation	Platelet binding inhibitors
DE3886175T2 (de) *	1987-11-18	1994-04-07	Univ Temple	Trigramin, ein Polypeptid, das die Aggregation der Blutplättchen hemmt.

1989
- 1989-04-12 NZ NZ228710A patent/NZ228710A/xx unknown
- 1989-04-13 IL IL89938A patent/IL89938A0/xx unknown
- 1989-04-17 ES ES89200967T patent/ES2063113T3/es not_active Expired - Lifetime
- 1989-04-17 EP EP89200967A patent/EP0338634B1/en not_active Expired - Lifetime
- 1989-04-17 AT AT89200967T patent/ATE103931T1/de not_active IP Right Cessation
- 1989-04-17 DE DE68914316T patent/DE68914316T2/de not_active Expired - Fee Related
- 1989-04-20 DK DK192189A patent/DK192189A/da unknown
- 1989-04-20 PT PT90321A patent/PT90321B/pt not_active IP Right Cessation
- 1989-04-21 AU AU33299/89A patent/AU627724B2/en not_active Ceased
- 1989-04-21 KR KR1019890005261A patent/KR900016261A/ko not_active Application Discontinuation
- 1989-04-21 JP JP1100330A patent/JPH02138298A/ja active Pending
- 1989-04-21 NO NO89891662A patent/NO891662L/no unknown
- 1989-04-21 FI FI891916A patent/FI891916A/fi not_active Application Discontinuation
- 1989-04-22 CN CN89104408A patent/CN1039441A/zh active Pending

Also Published As

Publication number	Publication date
PT90321B (pt)	1994-08-31
NZ228710A (en)	1992-10-28
ATE103931T1 (de)	1994-04-15
NO891662L (no)	1989-10-23
DE68914316D1 (de)	1994-05-11
NO891662D0 (no)	1989-04-21
JPH02138298A (ja)	1990-05-28
AU3329989A (en)	1990-02-15
FI891916A (fi)	1989-10-23
FI891916A0 (fi)	1989-04-21
KR900016261A (ko)	1990-11-13
EP0338634A2 (en)	1989-10-25
ES2063113T3 (es)	1995-01-01
EP0338634A3 (en)	1991-05-29
IL89938A0 (en)	1989-12-15
CN1039441A (zh)	1990-02-07
DK192189A (da)	1989-10-23
EP0338634B1 (en)	1994-04-06
DE68914316T2 (de)	1994-09-08
DK192189D0 (da)	1989-04-20
AU627724B2 (en)	1992-09-03

Legal Events

Date

Code

Title

Description

1994-08-31

FG3A

Patent granted, date of granting

Effective date: 19940202

2002-11-29

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20020831

Publication	Publication Date	Title
PT90321A (pt)	1989-11-10	Processo para a preparacao de polipeptideos de veneno de vibora
WO1989009787A3 (en)	1990-02-08	Osteogenic devices
CA2168429A1 (en)	1995-02-09	Expression of fusion polypeptides transported out of cytoplasm without leader sequences
EP0324647A3 (en)	1990-02-28	Vector for the expression of fusion proteins and protein immunogens
DK564989A (da)	1990-05-12	Bindingsproteiner
EP0433371A4 (en)	1991-10-30	Fusion protein of paramyxovirus, method of production using recombinant baculovirus expression vector, vaccine comprising such protein and use thereof
ATE62252T1 (de)	1991-04-15	Herstellung von peptiden und deren verwendung.
ZA877911B (en)	1988-04-25	Human apolipoprotein ai,and variant form of the same expressed in escherichia coli
ATE501254T1 (de)	2011-03-15	P- selectin ligandenprotein
DE3686579D1 (en)	1992-10-01	Prokaryotisches expressionssystem.
ATE102994T1 (de)	1994-04-15	Verfahren zur herstellung von proteinen.
ATE109827T1 (de)	1994-08-15	Verfahren zur herstellung von peptiden, dazu zu verwendendes rekombinantes plasmid und mit diesem plasmid transformierte myelomzellen.
SE8801723D0 (sv)	1988-05-06	Fibronectin binding protein as well as its preparation
DE59109235D1 (de)	2002-05-29	Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
DE69534738D1 (de)	2006-04-06	Leukocyten-aktivierender Faktor
CA2088478A1 (en)	1992-02-03	Cloning and expression of a rhoptry associated protein of p. falciparum
DE68917520D1 (de)	1994-09-22	Verfahren und Systeme zur Herstellung von HIV-Antigenen.
ATE76081T1 (de)	1992-05-15	Verfahren zur herstellung von dipeptiden mit nterminalen nichtproteinogenen aminosaeuren.
TH14583EX (th)	1994-08-26	จีนที่มีรหัสของเมกะคาริโอไซท์โพเทนชิเอเตอร์
ATE91303T1 (de)	1993-07-15	Verfahren zur herstellung von peptiden durch spezifische spaltung von gentechnisch gewonnenen fusionsproteinen mit collagenasen.