PT888293E - N-acilaminoalquilhidrazinocarboximidamidas - Google Patents

N-acilaminoalquilhidrazinocarboximidamidas

Info

Publication number
PT888293E
PT888293E PT96945113T PT96945113T PT888293E PT 888293 E PT888293 E PT 888293E PT 96945113 T PT96945113 T PT 96945113T PT 96945113 T PT96945113 T PT 96945113T PT 888293 E PT888293 E PT 888293E
Authority
PT
Portugal
Prior art keywords
carbon atoms
composition
group containing
inhibiting
protein
Prior art date
Application number
PT96945113T
Other languages
English (en)
Inventor
Peter C Ulrich
Dilip R Wagle
Original Assignee
Alteon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/771,959 external-priority patent/US5877217A/en
Application filed by Alteon Inc filed Critical Alteon Inc
Publication of PT888293E publication Critical patent/PT888293E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
PT96945113T 1995-12-26 1996-12-26 N-acilaminoalquilhidrazinocarboximidamidas PT888293E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US922095P 1995-12-26 1995-12-26
US61840796A 1996-03-19 1996-03-19
US08/771,959 US5877217A (en) 1995-12-26 1996-12-23 N-acylaminoalkyl-hydrazinecarboximidamides

Publications (1)

Publication Number Publication Date
PT888293E true PT888293E (pt) 2002-07-31

Family

ID=27358809

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96945113T PT888293E (pt) 1995-12-26 1996-12-26 N-acilaminoalquilhidrazinocarboximidamidas

Country Status (15)

Country Link
EP (1) EP0888293B1 (pt)
JP (1) JP2000502684A (pt)
CN (1) CN1209117A (pt)
AT (1) ATE215068T1 (pt)
AU (1) AU720796B2 (pt)
BR (1) BR9612304A (pt)
CA (1) CA2241746A1 (pt)
DE (1) DE69620253T2 (pt)
DK (1) DK0888293T3 (pt)
ES (1) ES2174132T3 (pt)
NO (1) NO982976L (pt)
NZ (1) NZ326238A (pt)
PT (1) PT888293E (pt)
TW (1) TW502012B (pt)
WO (1) WO1997023447A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
MX2008014024A (es) 2006-05-04 2008-11-14 Boehringer Ingelheim Int Formas poliformas.
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
BRPI0916997A2 (pt) 2008-08-06 2020-12-15 Boehringer Ingelheim International Gmbh Inibidor de dpp-4 e seu uso
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
US8513264B2 (en) 2008-09-10 2013-08-20 Boehringer Ingelheim International Gmbh Combination therapy for the treatment of diabetes and related conditions
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
CN107011345A (zh) 2008-12-23 2017-08-04 勃林格殷格翰国际有限公司 有机化合物的盐形式
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
EP3646859A1 (en) 2009-11-27 2020-05-06 Boehringer Ingelheim International GmbH Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
AU2011249722B2 (en) 2010-05-05 2015-09-17 Boehringer Ingelheim International Gmbh Combination therapy
BR112012032579B1 (pt) 2010-06-24 2021-05-11 Boehringer Ingelheim International Gmbh uso de linagliptina e composição farmacêutica compreendendo linagliptina e insulina basal de longa duração
US9034883B2 (en) 2010-11-15 2015-05-19 Boehringer Ingelheim International Gmbh Vasoprotective and cardioprotective antidiabetic therapy
HUE043540T2 (hu) 2011-07-15 2019-08-28 Boehringer Ingelheim Int Szubsztituált dimer kinazolin-származék, elõállítása, valamint alkalmazása 1-es és 2-es típusú cukorbetegség kezelésére szolgáló gyógyászati készítményekben
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
EP3685839A1 (en) 2012-05-14 2020-07-29 Boehringer Ingelheim International GmbH Linagliptin for use in the treatment of albuminuria and kidney related diseases
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
ES2950384T3 (es) 2014-02-28 2023-10-09 Boehringer Ingelheim Int Uso médico de un inhibidor de DPP-4
BR112018072401A2 (pt) 2016-06-10 2019-02-19 Boehringer Ingelheim International Gmbh combinações de linagliptina e metformina

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758583A (en) * 1984-03-19 1988-07-19 The Rockefeller University Method and agents for inhibiting protein aging

Also Published As

Publication number Publication date
EP0888293A1 (en) 1999-01-07
WO1997023447A1 (en) 1997-07-03
TW502012B (en) 2002-09-11
NZ326238A (en) 1999-11-29
ATE215068T1 (de) 2002-04-15
AU720796B2 (en) 2000-06-15
AU1356097A (en) 1997-07-17
CN1209117A (zh) 1999-02-24
CA2241746A1 (en) 1997-07-03
DE69620253T2 (de) 2002-09-19
BR9612304A (pt) 1999-07-13
DK0888293T3 (da) 2002-04-22
EP0888293B1 (en) 2002-03-27
JP2000502684A (ja) 2000-03-07
NO982976L (no) 1998-08-26
DE69620253D1 (en) 2002-05-02
ES2174132T3 (es) 2002-11-01
NO982976D0 (no) 1998-06-26

Similar Documents

Publication Publication Date Title
DE69620253T2 (de) N-acylaminoalkylhydrazinecarboximidamide
ATE112165T1 (de) Verfahren und mittel zur hemmung des proteinveraltens.
WO1993014750A3 (en) Amino acids useful as inhibitors of the advanced glycosylation of proteins
NZ312840A (en) Ketoheterocyclic inhibitors of factor Xa
RU94046457A (ru) Производные аспартама, способ их получения и содержащее их подслащивающее средство
HK1039488A1 (en) Tricylic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases.
PT1004578E (pt) Derivados hidroxamida do acido 5-oxo-pirrolidino-2-carboxilico
MY135057A (en) Dolastatin 15 derivatives
EA199800773A1 (ru) Производные пирролопирролона в качестве ингибиторов нейтрофильной эластазы
EA199800378A1 (ru) Новый способ получения фенилимидазолидиновых производных
AU3895689A (en) Cyclic sulfur-containing amino acid derivatives
DE69718775D1 (de) 1,2,4-triazinderivate zur inhibierung der proteinglycosylierung
WO1997042175B1 (en) Substituted imidazolium salts and their use for the inhibition of protein ageing
DE69715218D1 (de) Substituierte imidazoliunsalze und deren verwendung zur hemmung der proteinalterung
AU686104B2 (en) Substituted amidinonaphthyl ester derivatives
BR8303032A (pt) Sililoxialcano-azois, processo para sua preparacao, composicoes praguicidas, processo para o combate ou protecao de uma infestacao por microorganismo e processo para a preparacao de uma composicao
DK0835265T3 (da) Blodpladeaggregeringsinhibitorer indeholdende C-terminale aminosyrerester med aminerge sidekæder
DE69622393D1 (de) Neue verwendung von pyrazolopyridinverbindungen
RU94035756A (ru) Производные имидазола, являющиеся ингибиторами питокинов, способы их получения, фармацевтическая композиция