PT84105B - Processo para a preparacao de fenilcarbamidas ou carbamatos susbtituidos possuindo uma cadeia lateral azabiciclica e de composicoes farmaceuticas - Google Patents

Processo para a preparacao de fenilcarbamidas ou carbamatos susbtituidos possuindo uma cadeia lateral azabiciclica e de composicoes farmaceuticas

Info

Publication number
PT84105B
PT84105B PT84105A PT8410587A PT84105B PT 84105 B PT84105 B PT 84105B PT 84105 A PT84105 A PT 84105A PT 8410587 A PT8410587 A PT 8410587A PT 84105 B PT84105 B PT 84105B
Authority
PT
Portugal
Prior art keywords
phenylarbamides
azabicylic
susbtituted
carbamates
possessing
Prior art date
Application number
PT84105A
Other languages
English (en)
Other versions
PT84105A (en
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868600978A external-priority patent/GB8600978D0/en
Priority claimed from GB868626042A external-priority patent/GB8626042D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of PT84105A publication Critical patent/PT84105A/pt
Publication of PT84105B publication Critical patent/PT84105B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT84105A 1986-01-16 1987-01-14 Processo para a preparacao de fenilcarbamidas ou carbamatos susbtituidos possuindo uma cadeia lateral azabiciclica e de composicoes farmaceuticas PT84105B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868600978A GB8600978D0 (en) 1986-01-16 1986-01-16 Compounds
GB868626042A GB8626042D0 (en) 1986-10-31 1986-10-31 Compounds

Publications (2)

Publication Number Publication Date
PT84105A PT84105A (en) 1987-02-01
PT84105B true PT84105B (pt) 1989-07-31

Family

ID=26290226

Family Applications (1)

Application Number Title Priority Date Filing Date
PT84105A PT84105B (pt) 1986-01-16 1987-01-14 Processo para a preparacao de fenilcarbamidas ou carbamatos susbtituidos possuindo uma cadeia lateral azabiciclica e de composicoes farmaceuticas

Country Status (6)

Country Link
US (1) US4797387A (pt)
EP (1) EP0235878A3 (pt)
AU (1) AU603350B2 (pt)
DK (1) DK17787A (pt)
NZ (1) NZ218934A (pt)
PT (1) PT84105B (pt)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
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US5204356A (en) * 1985-07-24 1993-04-20 Glaxo Group Limited Treatment of anxiety
GB8518658D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Medicaments
HU895334D0 (en) * 1986-07-30 1990-01-28 Sandoz Ag Process for the preparation of nasal pharmaceutical compositions
DE3785507T2 (de) * 1986-07-31 1993-07-29 Beecham Group Plc Azabicyclische verbindungen, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung.
GB8701022D0 (en) * 1987-01-19 1987-02-18 Beecham Group Plc Treatment
DK202388A (da) * 1987-04-15 1988-10-16 Beecham Group Plc Azabicycliske forbindelser og fremgangsmaade til fremstilling deraf
GB8723157D0 (en) * 1987-10-02 1987-11-04 Beecham Group Plc Compounds
GB2225574B (en) * 1987-12-24 1991-04-24 Wyeth John & Brother Ltd Heterocyclic compounds
IE62231B1 (en) * 1987-12-24 1995-01-11 Wyeth John & Brother Ltd Heterocyclic compounds
GB8808926D0 (en) * 1988-04-15 1988-05-18 Beecham Group Plc Novel compounds
NZ230068A (en) * 1988-07-29 1991-07-26 Dainippon Pharmaceutical Co Indazole-3-carboxylic acid esters and amides of diaza compounds having 6,7, or 8 ring members: preparatory processes and pharmaceutical compositions
US5166341A (en) * 1988-07-29 1992-11-24 Dainippon Pharmaceutical Co., Ltd. 6-amino-1,4-hexahydro-1H-diazepine derivatives
DE3878235T2 (de) * 1988-08-04 1993-06-03 Synthelabo Antischizophren-wirksame s-n-(1-azabicyclo (2.2.2.)oct-3-yl)benzamide und thiobenzamide.
JPH0393762A (ja) * 1989-09-04 1991-04-18 Wako Pure Chem Ind Ltd ４‐ハロゲノ‐２‐アルコキシイミノ‐３‐オキソ脂肪酸の製造方法
DK443489D0 (da) * 1989-09-08 1989-09-08 Ferrosan As Substituerede urinstofforbindelser, deres fremstilling og anvendelse
DK40890D0 (da) * 1990-02-16 1990-02-16 Ferrosan As Substituerede urinstofforbindelser, deres fremstilling og anvendelse
GB9106571D0 (en) * 1991-03-27 1991-05-15 Erba Carlo Spa Derivatives of substituted imidazol-2-one and process for their preparation
US5028614A (en) * 1990-03-30 1991-07-02 Merrell Dow Pharmaceuticals Inc. Hydroxymethyl-indolizidines and quinolizidines and their use as α-glucosidase I inhibitors
US5223613A (en) * 1990-04-27 1993-06-29 G. D. Searle & Co. Azatetracycle compounds and process of preparing same
US5140023A (en) * 1990-04-27 1992-08-18 G. D. Searle & Co. Azatetracycle compounds
US5137893A (en) * 1991-03-07 1992-08-11 G. D. Searle & Co. Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5219850A (en) * 1991-03-07 1993-06-15 G. D. Searle & Co. Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5516782A (en) * 1991-03-07 1996-05-14 G. D. Searle & Co. New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
AU1578692A (en) * 1991-03-07 1992-10-06 G.D. Searle & Co. New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
US5260303A (en) * 1991-03-07 1993-11-09 G. D. Searle & Co. Imidazopyridines as serotonergic 5-HT3 antagonists
US5227377A (en) * 1991-03-07 1993-07-13 G. D. Searle & Co. Meso-azacyclic amides of certain bicyclic carboxylic acids
US5196547A (en) * 1991-03-07 1993-03-23 G. D. Searle & Co. Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5234921A (en) * 1991-03-07 1993-08-10 G. D. Searle & Co. Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof as pharmaceuticals
GB9121835D0 (en) * 1991-10-15 1991-11-27 Smithkline Beecham Plc Pharmaceuticals
US5236931A (en) * 1992-03-26 1993-08-17 A. H. Robins Company, Incorporated 2-substituted benzamide and benzoate derivatives of 3-aminoquinuclidine and 3-quinuclidinol
GB9212486D0 (en) * 1992-06-12 1992-07-22 Erba Carlo Spa Derivatives of substituted imidazo benzoxazin-1-one and process for their preparation
EP0742208A1 (en) * 1995-05-05 1996-11-13 Grelan Pharmaceutical Co., Ltd. 2-Ureido-benzamide derivatives
AU724780B2 (en) * 1996-03-20 2000-09-28 Wake Forest University Sigma-2 receptors as biomarkers of tumor cell proliferation
US6676925B1 (en) * 1996-03-20 2004-01-13 Wake Forest University Sigma-2 receptors as biomarkers of tumor cell proliferation
FR2791678B1 (fr) 1999-03-30 2001-05-04 Synthelabo Derives de 1,4-diazabicyclo [3.2.2] nonane-4-carboxylates et -carboxamides, leur preparation et leur application en therapeutique
ATE256682T1 (de) 2000-04-27 2004-01-15 Univ Wake Forest Health Sciences Sigma-2 rezeptoren als biomarkierer der tumorzellenproliferation
PE20021019A1 (es) 2001-04-19 2002-11-13 Upjohn Co Grupos azabiciclicos sustituidos
US7041674B2 (en) * 2002-11-26 2006-05-09 Boehringer Ingelhiem Pharma Gmbh & Co. Kg Carbamic acid esters with anticholinergic activity
US20070238751A1 (en) * 2004-04-07 2007-10-11 Laine Dramane I Muscarinic Acetylcholine Receptor Antagonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2658067A (en) * 1953-11-03 Substituted carbamic acdj esters
US4082756A (en) * 1971-04-16 1978-04-04 Colgate-Palmolive Company Quaternary quinuclidinium carbamates and thiocarbamates
DE2645781A1 (de) * 1976-10-09 1978-04-13 Basf Ag Neue in 6-stellung substituierte tropinone und verfahren zu ihrer herstellung
US4432983A (en) * 1981-04-30 1984-02-21 Research Corporation Conformationally restricted histamine H2 -receptor antagonists containing a tropane ring
GB2100259B (en) * 1981-06-13 1984-10-31 Merrell Toraude & Co Treatment of migraine with tropyl benzoate derivatives
IE56226B1 (en) * 1982-04-14 1991-05-22 Beecham Group Plc Substituted azabicyclo compounds,process for their preparation and pharmaceutical compositions containing them
EP0095262B1 (en) * 1982-05-11 1986-12-03 Beecham Group Plc Azabicycloalkane derivatives, their preparation and medicaments containing them
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
GB8302483D0 (en) * 1983-01-29 1983-03-02 Beecham Group Plc Compounds
EP0158265A2 (en) * 1984-04-13 1985-10-16 Beecham Group Plc Benzamide and anilide derivatives
IL72788A (en) * 1984-08-28 1989-07-31 Israel State Bis quaternary oxy-bis methylene(or trimethylene)bis-n-quinuclidines,pyridines and piperidines,their preparation and antidotes against organophosphorus and carbamate poisoning containing them

Also Published As

Publication number Publication date
NZ218934A (en) 1990-04-26
DK17787D0 (da) 1987-01-14
AU6756787A (en) 1987-07-23
EP0235878A3 (en) 1989-06-14
US4797387A (en) 1989-01-10
PT84105A (en) 1987-02-01
AU603350B2 (en) 1990-11-15
EP0235878A2 (en) 1987-09-09
DK17787A (da) 1987-07-17

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Legal Events

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Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19920731