PT828483E - Utilizacao de derivados de tropolona como inibidores da enzima inositol monofosfatase - Google Patents

Utilizacao de derivados de tropolona como inibidores da enzima inositol monofosfatase

Info

Publication number
PT828483E
PT828483E PT96916132T PT96916132T PT828483E PT 828483 E PT828483 E PT 828483E PT 96916132 T PT96916132 T PT 96916132T PT 96916132 T PT96916132 T PT 96916132T PT 828483 E PT828483 E PT 828483E
Authority
PT
Portugal
Prior art keywords
inhibitors
inositol monophosphatase
tropolone derivatives
enzyme
enzyme inositol
Prior art date
Application number
PT96916132T
Other languages
English (en)
Inventor
Khalid Islam
Federica Sponga
Stefania Stefanelli
Maurizio Denaro
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of PT828483E publication Critical patent/PT828483E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
PT96916132T 1995-05-24 1996-05-20 Utilizacao de derivados de tropolona como inibidores da enzima inositol monofosfatase PT828483E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95107936 1995-05-24

Publications (1)

Publication Number Publication Date
PT828483E true PT828483E (pt) 2003-06-30

Family

ID=8219287

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96916132T PT828483E (pt) 1995-05-24 1996-05-20 Utilizacao de derivados de tropolona como inibidores da enzima inositol monofosfatase

Country Status (13)

Country Link
US (1) US5990160A (pt)
EP (1) EP0828483B1 (pt)
JP (1) JP4054061B2 (pt)
KR (2) KR100412753B1 (pt)
AT (1) ATE231721T1 (pt)
AU (1) AU698059B2 (pt)
CA (1) CA2221771C (pt)
DE (1) DE69626010T2 (pt)
DK (1) DK0828483T3 (pt)
ES (1) ES2186782T3 (pt)
PT (1) PT828483E (pt)
SI (1) SI0828483T1 (pt)
WO (1) WO1996037197A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689342B1 (en) * 2002-07-29 2004-02-10 Warner-Lambert Company Oral care compositions comprising tropolone compounds and essential oils and methods of using the same
GB201102248D0 (en) 2011-02-09 2011-03-23 Isis Innovation Treatment of bipolar disorder

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56147704A (en) * 1980-04-07 1981-11-16 Rowaale Keshohin Kk Dermatological composition
US4981980A (en) * 1989-09-14 1991-01-01 Merck & Co., Inc. Drug for treating manic depression

Also Published As

Publication number Publication date
EP0828483B1 (en) 2003-01-29
KR20040004513A (ko) 2004-01-13
JP4054061B2 (ja) 2008-02-27
AU5900096A (en) 1996-12-11
AU698059B2 (en) 1998-10-22
WO1996037197A1 (en) 1996-11-28
CA2221771A1 (en) 1996-11-28
US5990160A (en) 1999-11-23
DK0828483T3 (da) 2003-05-19
ATE231721T1 (de) 2003-02-15
SI0828483T1 (en) 2003-06-30
EP0828483A1 (en) 1998-03-18
CA2221771C (en) 2007-09-18
DE69626010T2 (de) 2003-07-24
ES2186782T3 (es) 2003-05-16
JPH11505817A (ja) 1999-05-25
DE69626010D1 (de) 2003-03-06
KR19990021882A (ko) 1999-03-25
KR100412753B1 (ko) 2004-04-21

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