PT81786B - Processo para a preparacao de inibidores da dopamina-beta-hidroxilase - Google Patents
Processo para a preparacao de inibidores da dopamina-beta-hidroxilaseInfo
- Publication number
- PT81786B PT81786B PT81786A PT8178686A PT81786B PT 81786 B PT81786 B PT 81786B PT 81786 A PT81786 A PT 81786A PT 8178686 A PT8178686 A PT 8178686A PT 81786 B PT81786 B PT 81786B
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- dopamine
- beta
- alkyl
- hydroxylase inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/689,680 US4728741A (en) | 1985-01-08 | 1985-01-08 | 1-substituted-2-mercapto benzimidazole compounds and intermediates |
Publications (2)
Publication Number | Publication Date |
---|---|
PT81786A PT81786A (en) | 1986-02-01 |
PT81786B true PT81786B (pt) | 1988-05-27 |
Family
ID=24769487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT81786A PT81786B (pt) | 1985-01-08 | 1986-01-03 | Processo para a preparacao de inibidores da dopamina-beta-hidroxilase |
Country Status (12)
Country | Link |
---|---|
US (1) | US4728741A (pt) |
EP (1) | EP0190817B1 (pt) |
JP (1) | JPS61161267A (pt) |
AT (1) | ATE56207T1 (pt) |
AU (2) | AU588562B2 (pt) |
CA (1) | CA1269668A (pt) |
DE (1) | DE3673835D1 (pt) |
DK (1) | DK2886A (pt) |
ES (1) | ES8703844A1 (pt) |
GR (1) | GR860018B (pt) |
PT (1) | PT81786B (pt) |
ZA (1) | ZA8665B (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61151176A (ja) * | 1984-12-24 | 1986-07-09 | Sumitomo Chem Co Ltd | ベンズイミダゾール誘導体およびそれを有効成分とする殺虫、殺ダニ剤 |
JPS63101380A (ja) * | 1986-10-17 | 1988-05-06 | Zeria Shinyaku Kogyo Kk | 新規な2−メルカプトベンズイミダゾ−ル誘導体、それらの製造法およびそれらを有効成分として含有する抗潰瘍剤 |
IT1226100B (it) * | 1988-07-07 | 1990-12-10 | Dompe Farmaceutici Spa | Derivati benzimidazolici farmacologicamente attivi. |
GB8904174D0 (en) * | 1989-02-23 | 1989-04-05 | British Bio Technology | Compounds |
JPH05504969A (ja) * | 1990-02-13 | 1993-07-29 | メルク・エンド・カムパニー・インコーポレーテツド | 置換ベンジル要素を含有するアンギオテンシン2アンタゴニスト類 |
US5106863A (en) * | 1990-03-26 | 1992-04-21 | Ortho Pharmaceutical Corporation | Substituted imidazole and pyridine derivatives |
EP0474109A1 (de) * | 1990-09-03 | 1992-03-11 | Richter Gedeon Vegyeszeti Gyar R.T. | Neue 5-Benzyl-substituierte Benzimidazolin-2-Thion-Derivate und Verfahren zu ihrer Herstellung |
GB9101448D0 (en) * | 1991-01-23 | 1991-03-06 | Cox John H | Improved door assembly |
TW300219B (pt) * | 1991-09-14 | 1997-03-11 | Hoechst Ag | |
US6114532A (en) * | 1998-02-03 | 2000-09-05 | Boehringer Ingelheim Pharma Kg | Bicyclic heterocycles, the preparation thereof, and their use as pharmaceuticals |
CA2530081A1 (en) * | 2003-07-01 | 2005-01-13 | Merck & Co., Inc. | Ophthalmic compositions for treating ocular hypertension |
DE102007037579B4 (de) * | 2007-08-09 | 2012-05-16 | Emc Microcollections Gmbh | Neue Benzimidazol-2-yl-alkylamine und ihre Anwendung als mikrobizide Wirkstoffe |
JOP20190049A1 (ar) * | 2016-09-23 | 2019-03-20 | Bial Portela & C? S A | مثبطات دوبامين-b-هيدروكسيلاز |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL302847A (pt) * | 1963-01-10 | |||
DE1542886A1 (de) * | 1966-10-04 | 1970-05-14 | Bayer Ag | Fungizide Mittel |
BE732508A (pt) * | 1968-05-08 | 1969-10-16 | ||
DE2235093C2 (de) * | 1972-07-18 | 1974-07-04 | Bayer Ag, 5090 Leverkusen | Korrosionsschutzmittel |
FR2521141A1 (fr) * | 1982-02-09 | 1983-08-12 | Rhone Poulenc Agrochimie | Nouveaux derives du cyano-2 benzimidazole, leur preparation et leur utilisation comme fongicides |
US4492708A (en) * | 1982-09-27 | 1985-01-08 | Eli Lilly And Company | Antiviral benzimidazoles |
GB8307865D0 (en) * | 1983-03-22 | 1983-04-27 | Fujisawa Pharmaceutical Co | Benzimidazole derivatives |
EP0269230A1 (en) * | 1986-10-09 | 1988-06-01 | The Wellcome Foundation Limited | Heterocyclic compounds |
-
1985
- 1985-01-08 US US06/689,680 patent/US4728741A/en not_active Expired - Fee Related
-
1986
- 1986-01-02 AU AU51801/86A patent/AU588562B2/en not_active Ceased
- 1986-01-03 PT PT81786A patent/PT81786B/pt not_active IP Right Cessation
- 1986-01-03 DK DK2886A patent/DK2886A/da not_active Application Discontinuation
- 1986-01-06 CA CA000499050A patent/CA1269668A/en not_active Expired - Lifetime
- 1986-01-06 ZA ZA8665A patent/ZA8665B/xx unknown
- 1986-01-07 EP EP86300056A patent/EP0190817B1/en not_active Expired - Lifetime
- 1986-01-07 AT AT86300056T patent/ATE56207T1/de not_active IP Right Cessation
- 1986-01-07 JP JP61001957A patent/JPS61161267A/ja active Pending
- 1986-01-07 GR GR860018A patent/GR860018B/el unknown
- 1986-01-07 DE DE8686300056T patent/DE3673835D1/de not_active Expired - Fee Related
- 1986-01-07 ES ES550699A patent/ES8703844A1/es not_active Expired
-
1989
- 1989-07-05 AU AU37887/89A patent/AU3788789A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
GR860018B (en) | 1986-04-29 |
ES8703844A1 (es) | 1987-03-01 |
EP0190817A1 (en) | 1986-08-13 |
JPS61161267A (ja) | 1986-07-21 |
ES550699A0 (es) | 1987-03-01 |
AU5180186A (en) | 1986-07-17 |
AU588562B2 (en) | 1989-09-21 |
DK2886A (da) | 1986-07-09 |
CA1269668A (en) | 1990-05-29 |
PT81786A (en) | 1986-02-01 |
EP0190817B1 (en) | 1990-09-05 |
AU3788789A (en) | 1989-10-19 |
DK2886D0 (da) | 1986-01-03 |
ZA8665B (en) | 1986-08-27 |
US4728741A (en) | 1988-03-01 |
ATE56207T1 (de) | 1990-09-15 |
DE3673835D1 (de) | 1990-10-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19930531 |