PT780375E - 3-¬(benzilo substituido em 5)amino|-2-phenilpiperidinas como antagonistas da substancia p - Google Patents

3-¬(benzilo substituido em 5)amino|-2-phenilpiperidinas como antagonistas da substancia p

Info

Publication number
PT780375E
PT780375E PT96203560T PT96203560T PT780375E PT 780375 E PT780375 E PT 780375E PT 96203560 T PT96203560 T PT 96203560T PT 96203560 T PT96203560 T PT 96203560T PT 780375 E PT780375 E PT 780375E
Authority
PT
Portugal
Prior art keywords
alkyl
halo
disorders
cycloalkyl
hydrogen
Prior art date
Application number
PT96203560T
Other languages
English (en)
Inventor
Hiroaki Wakabayashi
Yuji Shishido
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT780375E publication Critical patent/PT780375E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT96203560T 1995-12-21 1996-12-16 3-¬(benzilo substituido em 5)amino|-2-phenilpiperidinas como antagonistas da substancia p PT780375E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB9501148 1995-12-21

Publications (1)

Publication Number Publication Date
PT780375E true PT780375E (pt) 2002-12-31

Family

ID=11004393

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96203560T PT780375E (pt) 1995-12-21 1996-12-16 3-¬(benzilo substituido em 5)amino|-2-phenilpiperidinas como antagonistas da substancia p

Country Status (8)

Country Link
US (1) US5789423A (pt)
EP (1) EP0780375B1 (pt)
AT (1) ATE223896T1 (pt)
CA (1) CA2193468C (pt)
DE (1) DE69623580T2 (pt)
DK (1) DK0780375T3 (pt)
ES (1) ES2180693T3 (pt)
PT (1) PT780375E (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW340842B (en) * 1995-08-24 1998-09-21 Pfizer Substituted benzylaminopiperidine compounds
CA2291734A1 (en) * 1997-06-27 1999-01-07 Merck Sharp & Dohme Limited Substituted 3-(benzylamino)piperidine derivatives and their use as therapeutic agents
HUP0201135A3 (en) * 1999-05-06 2003-05-28 Pfizer Prod Inc Substituted benzolactam compounds, use of them for producing pharmaceutical compositions and pharmaceutical compositions containing them
CN1466573A (zh) 2000-09-26 2004-01-07 田边制药株式会社 5-苯基苄胺化合物、其制备方法以及其合成中间体
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
DK3107901T3 (da) 2014-02-19 2020-06-22 Piramal Entpr Ltd Forbindelser til brug som gpr120 agonister
US10273230B2 (en) 2014-07-25 2019-04-30 Piramal Enterprises Limited Substituted phenyl alkanoic acid compounds as GPR120 agonists and uses thereof
WO2016038540A1 (en) 2014-09-11 2016-03-17 Piramal Enterprises Limited Fused heterocyclic compounds as gpr120 agonists

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4680283A (en) 1984-09-26 1987-07-14 Merck & Co., Inc. Analogs of substance P and eledoisin
DE3602169A1 (de) 1986-01-22 1987-07-23 Schering Ag Neue alkan- und alkoxyalkanderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende insektizide und akarizide mittel
UA41251C2 (uk) 1990-01-04 2001-09-17 Пфайзер, Інк. Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі
US5232929A (en) 1990-11-28 1993-08-03 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
US5364943A (en) 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
JPH0794440B2 (ja) * 1991-03-26 1995-10-11 フアイザー・インコーポレイテツド 置換ピペリジンの立体選択的製造
DE69213451T2 (de) 1991-06-20 1997-01-09 Pfizer Inc., New York Fluoralkoxybenzylaminoderivate stickstoffhaltiger heterocyclen
ES2164072T3 (es) * 1992-08-19 2002-02-16 Pfizer Heterociclos no aromaticos que contienen nitrogeno sustituidos con bencilamino.
GB9305718D0 (en) * 1993-03-19 1993-05-05 Glaxo Group Ltd Medicaments
IL109646A0 (en) 1993-05-19 1994-08-26 Pfizer Heteroatom substituted alkyl benzylamino-quinuclidines

Also Published As

Publication number Publication date
CA2193468C (en) 2001-04-24
CA2193468A1 (en) 1997-06-22
ES2180693T3 (es) 2003-02-16
DE69623580T2 (de) 2003-01-09
DE69623580D1 (de) 2002-10-17
DK0780375T3 (da) 2002-10-07
US5789423A (en) 1998-08-04
ATE223896T1 (de) 2002-09-15
EP0780375B1 (en) 2002-09-11
EP0780375A1 (en) 1997-06-25

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