PT72915B - Process for preparing 23-keto derivatives of c-076 coumpounds - Google Patents

Process for preparing 23-keto derivatives of c-076 coumpounds

Info

Publication number
PT72915B
PT72915B PT72915A PT7291581A PT72915B PT 72915 B PT72915 B PT 72915B PT 72915 A PT72915 A PT 72915A PT 7291581 A PT7291581 A PT 7291581A PT 72915 B PT72915 B PT 72915B
Authority
PT
Portugal
Prior art keywords
compounds
chromic acid
derivatives
keto
oxidized
Prior art date
Application number
PT72915A
Other languages
English (en)
Other versions
PT72915A (en
Inventor
Helmut H Mrozik
John G Macconnell
August J Kemp
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT72915A publication Critical patent/PT72915A/pt
Publication of PT72915B publication Critical patent/PT72915B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT72915A 1980-05-02 1981-04-24 Process for preparing 23-keto derivatives of c-076 coumpounds PT72915B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/146,725 US4289760A (en) 1980-05-02 1980-05-02 23-Keto derivatives of C-076 compounds

Publications (2)

Publication Number Publication Date
PT72915A PT72915A (en) 1981-05-01
PT72915B true PT72915B (en) 1983-02-16

Family

ID=22518711

Family Applications (1)

Application Number Title Priority Date Filing Date
PT72915A PT72915B (en) 1980-05-02 1981-04-24 Process for preparing 23-keto derivatives of c-076 coumpounds

Country Status (13)

Country Link
US (1) US4289760A (pt)
EP (1) EP0040913B1 (pt)
JP (1) JPS5718684A (pt)
AT (1) ATE8637T1 (pt)
AU (1) AU547211B2 (pt)
CA (1) CA1168605A (pt)
DE (1) DE3165016D1 (pt)
DK (1) DK193881A (pt)
ES (1) ES8207544A1 (pt)
GR (1) GR74875B (pt)
NZ (1) NZ196897A (pt)
PT (1) PT72915B (pt)
ZA (1) ZA812908B (pt)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57139012A (en) * 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4333925A (en) * 1981-05-11 1982-06-08 Merck & Co., Inc. Derivatives of C-076 compounds
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
US4510133A (en) * 1982-04-22 1985-04-09 Imperial Chemical Industries Plc Method for combating pests
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
US4582852A (en) * 1983-11-02 1986-04-15 Ciba-Geigy Corporation 14- and 15-hydroxy milbemycin derivatives for controlling plant and animal parasites
JPS60126289A (ja) * 1983-11-14 1985-07-05 Sankyo Co Ltd ミルベマイシン類の５−カ−ボネ−ト誘導体
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
AU596586B2 (en) * 1985-04-30 1990-05-10 American Cyanamid Company Chemical derivatives of antibiotics S541
IT1190285B (it) * 1985-04-30 1988-02-16 Glaxo Group Ltd Antibiotici macrolidi e procedimento per prepararli ed applicarli
US4789684A (en) * 1985-05-02 1988-12-06 Merck & Co., Inc. Anthelmintic fermentation products of microorganisms
ES8605582A1 (es) * 1985-12-11 1986-03-16 Antibioticos Sa Un procedimiento para la preparacion de avermectinas
IE61058B1 (en) * 1986-01-23 1994-09-21 American Cyanamid Co Macrolide antibiotics and their preparation
JP2577734B2 (ja) * 1986-03-12 1997-02-05 アメリカン・サイアナミツド・カンパニー マクロライド抗生物質
PH27415A (en) * 1986-03-12 1993-06-21 American Cyanamid Co Macrolide compounds
GB8606108D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
EP0259779B1 (en) * 1986-09-12 1994-08-10 American Cyanamid Company 23-Oxo (Keto) and 23-imino Derivatives of LL-F28249 Compounds
US4849446A (en) * 1986-09-12 1989-07-18 American Cyanamid Company 23-imino derivatives of 23-keto compounds
US4886784A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Novel 23-imino derivatives of 23-keto compounds
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
EP0260537A1 (en) * 1986-09-12 1988-03-23 American Cyanamid Company 13-Deoxy-23-oxo(keto) and 23-imino derivatives of 13-deoxy C-076-aglycone compounds
US4877888A (en) * 1986-09-12 1989-10-31 American Cyanamid Company 13-deoxy-23-imino derivatives of 13-deoxy C-076-aglycone compounds
US4886829A (en) * 1987-03-06 1989-12-12 American Cyanamid Company 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4906619A (en) * 1988-07-22 1990-03-06 Merck & Co., Inc. Alkyl avermectin derivatives
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
US5830875A (en) * 1989-10-30 1998-11-03 Merck & Co., Inc. 24-and 25-substituted avermectin and milbemycin derivatives
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
US5169839A (en) * 1990-05-11 1992-12-08 Merck & Co., Inc. Derivatives of 3'- and 3"-o-desmethyl avermectin compounds, compositions and methods of treating melmintic and parasitic infections
US5188944A (en) * 1990-06-22 1993-02-23 Merck & Co., Inc. Process for the glycosylation of avermectin agylcones
US5208222A (en) * 1991-03-28 1993-05-04 Merck & Co., Inc. 4"-and 4'-alkylthio avermectin derivatives
US5240915A (en) * 1991-10-15 1993-08-31 Merck & Co., Inc. Avermectin derivatives
RU2086552C1 (ru) * 1991-12-18 1997-08-10 Санкио Компани Лимитед Производные 13-(замещенного тио)ацетоксимилбемицина, способ их получения, инсектицидная композиция и способ защиты растений
US5229415A (en) * 1992-03-24 1993-07-20 Merck & Co., Inc. Alkylthio alkyl avermectins are active antiparasitic agents
IL107810A0 (en) * 1992-12-17 1994-02-27 Exxon Chemical Patents Inc Functionalized polymers and processes for the preparation thereof
DK0765879T3 (da) * 1995-09-29 2001-03-19 Sankyo Co 13-substituerede milbemycin 5-oximderivater, deres fremstilling og deres anvendelse over for insekter og andre skadedyr
RU2226531C1 (ru) 2000-04-27 2004-04-10 Санкио Компани, Лимитед 13-замещенные производные милбемицина, их получение и их применение против насекомых и других вредителей

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
US4172940A (en) * 1977-10-03 1979-10-30 Merck & Co., Inc. Purification of C-076 compounds by single column chromatography
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
US4171314A (en) * 1977-12-19 1979-10-16 Merck & Co., Inc. 13-Halo and 13-deoxy C-076 compounds
PH16612A (en) * 1977-12-19 1983-11-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds

Also Published As

Publication number Publication date
ZA812908B (en) 1982-12-29
DK193881A (da) 1981-11-03
ES501777A0 (es) 1982-09-16
CA1168605A (en) 1984-06-05
JPS5718684A (en) 1982-01-30
NZ196897A (en) 1984-09-28
JPH0254358B2 (pt) 1990-11-21
US4289760A (en) 1981-09-15
EP0040913B1 (en) 1984-07-25
ATE8637T1 (de) 1984-08-15
PT72915A (en) 1981-05-01
AU547211B2 (en) 1985-10-10
GR74875B (pt) 1984-07-12
EP0040913A1 (en) 1981-12-02
AU6973081A (en) 1981-11-05
DE3165016D1 (en) 1984-08-30
ES8207544A1 (es) 1982-09-16

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