PT714898E - Derivado de pirazolo¬1,5-a|pirimidina - Google Patents
Derivado de pirazolo¬1,5-a|pirimidinaInfo
- Publication number
- PT714898E PT714898E PT95920260T PT95920260T PT714898E PT 714898 E PT714898 E PT 714898E PT 95920260 T PT95920260 T PT 95920260T PT 95920260 T PT95920260 T PT 95920260T PT 714898 E PT714898 E PT 714898E
- Authority
- PT
- Portugal
- Prior art keywords
- halogen
- alkyl
- phenyl
- substituted
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13863594 | 1994-06-21 | ||
JP5399795 | 1995-03-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT714898E true PT714898E (pt) | 2002-04-29 |
Family
ID=26394734
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95920260T PT714898E (pt) | 1994-06-21 | 1995-06-05 | Derivado de pirazolo¬1,5-a|pirimidina |
Country Status (13)
Country | Link |
---|---|
US (1) | US5707997A (pt) |
EP (1) | EP0714898B1 (pt) |
KR (1) | KR100315837B1 (pt) |
CN (1) | CN1046730C (pt) |
AT (1) | ATE208776T1 (pt) |
AU (1) | AU680370B2 (pt) |
CA (1) | CA2169719C (pt) |
DE (1) | DE69523864T2 (pt) |
DK (1) | DK0714898T3 (pt) |
ES (1) | ES2164153T3 (pt) |
PT (1) | PT714898E (pt) |
TW (1) | TW307767B (pt) |
WO (1) | WO1995035298A1 (pt) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2206080A1 (en) * | 1995-09-28 | 1997-04-03 | Otsuka Pharmaceutical Factory, Inc. | Analgesic composition_of pryazolo{1,5-a}pyrimidine derivatives |
US6664261B2 (en) | 1996-02-07 | 2003-12-16 | Neurocrine Biosciences, Inc. | Pyrazolopyrimidines as CRF receptor antagonists |
US6060478A (en) * | 1996-07-24 | 2000-05-09 | Dupont Pharmaceuticals | Azolo triazines and pyrimidines |
US6191131B1 (en) | 1997-07-23 | 2001-02-20 | Dupont Pharmaceuticals Company | Azolo triazines and pyrimidines |
US7094782B1 (en) | 1996-07-24 | 2006-08-22 | Bristol-Myers Squibb Company | Azolo triazines and pyrimidines |
US6124289A (en) * | 1996-07-24 | 2000-09-26 | Dupont Pharmaceuticals Co. | Azolo triazines and pyrimidines |
US6313124B1 (en) | 1997-07-23 | 2001-11-06 | Dupont Pharmaceuticals Company | Tetrazine bicyclic compounds |
DK0915880T3 (da) * | 1996-07-24 | 2008-02-11 | Bristol Myers Squibb Pharma Co | Azolotriaziner og pyrimidiner |
US6197774B1 (en) * | 1997-03-14 | 2001-03-06 | Otsuka Pharmaceutical Co., Ltd. | Pyrimidine derivative |
CA2359041A1 (en) * | 1999-01-29 | 2000-08-03 | Sumitomo Chemical Co., Ltd. | Fat accumulation inhibitory agents |
WO2000059908A2 (en) | 1999-04-06 | 2000-10-12 | Du Pont Pharmaceuticals Company | Pyrazolopyrimidines as crf antagonists |
WO2000059907A2 (en) | 1999-04-06 | 2000-10-12 | Du Pont Pharmaceuticals Company | Pyrazolotriazines as crf antagonists |
US20020061897A1 (en) | 2000-03-30 | 2002-05-23 | Elliott Richard L. | Neuropeptide Y antagonists |
US6630476B2 (en) | 2000-07-07 | 2003-10-07 | Bristol-Myers Squibb Pharma Company | Pyrrolo [3,4-d] pyrimidines as corticotropin releasing factor (CRF) antagonists |
SE0102764D0 (sv) | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
US6833371B2 (en) * | 2001-11-01 | 2004-12-21 | Icagen, Inc. | Pyrazolopyrimidines |
US20040028716A1 (en) * | 2002-06-14 | 2004-02-12 | Marks Andrew R. | Use of Y-27632 as an agent to prevent restenosis after coronary artery angioplasty/stent implantation |
NZ539164A (en) * | 2002-09-04 | 2006-04-28 | Schering Corp | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
US7161003B1 (en) | 2002-09-04 | 2007-01-09 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
MY138201A (en) | 2002-09-04 | 2009-05-29 | Schering Corp | Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors |
US7078525B2 (en) * | 2002-09-04 | 2006-07-18 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
US8580782B2 (en) | 2002-09-04 | 2013-11-12 | Merck Sharp & Dohme Corp. | Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors |
EP1545533A1 (en) * | 2002-09-04 | 2005-06-29 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
US7205308B2 (en) * | 2002-09-04 | 2007-04-17 | Schering Corporation | Trisubstituted 7-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors |
MXPA05002572A (es) * | 2002-09-04 | 2005-09-08 | Schering Corp | Compuestos pirazolo[1,5-a]pirimidinas como inhibidores de cinasa depentes de ciclina. |
US7196078B2 (en) | 2002-09-04 | 2007-03-27 | Schering Corpoartion | Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors |
US7119200B2 (en) * | 2002-09-04 | 2006-10-10 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
US8673924B2 (en) | 2002-09-04 | 2014-03-18 | Merck Sharp & Dohme Corp. | Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors |
US6949895B2 (en) * | 2003-09-03 | 2005-09-27 | Axcelis Technologies, Inc. | Unipolar electrostatic quadrupole lens and switching methods for charged beam transport |
PE20051089A1 (es) * | 2004-01-22 | 2006-01-25 | Novartis Ag | Derivados de pirazolo [1,5-a] pirimidin-7-il-amina como inhibidores de quinasa de proteina |
WO2006040645A1 (en) * | 2004-10-11 | 2006-04-20 | Ranbaxy Laboratories Limited | N-(3,5-dichloropyridin-4-yl)-2,4,5-alkoxy and 2,3,4-alkoxy benzamide derivatives as pde-iv (phophodiesterase type-iv) inhibitors for the treatment of inflammatory diseases such as asthma |
GB0519957D0 (en) | 2005-09-30 | 2005-11-09 | Sb Pharmco Inc | Chemical compound |
TW200639163A (en) * | 2005-02-04 | 2006-11-16 | Genentech Inc | RAF inhibitor compounds and methods |
BRPI0607502A2 (pt) * | 2005-03-01 | 2016-11-01 | Basf Ag | compostos processo para a preparação dos mesmos, agente, semente, e, processo para combater fungos nocivos fitopatogênicos |
WO2006092428A2 (de) * | 2005-03-02 | 2006-09-08 | Basf Aktiengesellschaft | 2-substituierte 7-amino-azolopyrimidine, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen sowie sie enthaltende mittel |
WO2007032936A2 (en) | 2005-09-09 | 2007-03-22 | Schering Corporation | Azafused cyclin dependent kinase inhibitors |
TW200745123A (en) | 2005-10-06 | 2007-12-16 | Schering Corp | Pyrazolopyrimidines as protein kinase inhibitors |
NZ577814A (en) * | 2006-11-27 | 2012-03-30 | Lundbeck & Co As H | Imidazo[1,2-a]pyridine amide derivatives |
MX2009010523A (es) * | 2007-04-10 | 2009-12-15 | Lundbeck & Co As H | Análogos de amidas heteroarílicas como antagonistas de p2x7. |
WO2010116176A1 (en) | 2009-04-09 | 2010-10-14 | Astrazeneca Ab | Pyrazolo [4, 5-e] pyrimidine derivative and its use to treat diabetes and obesity |
JP2014530872A (ja) * | 2011-10-20 | 2014-11-20 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーGlaxoSmithKline LLC | サーチュイン調節因子としての置換された二環式アザ複素環およびアナログ |
RU2014120166A (ru) | 2011-10-20 | 2015-11-27 | ГЛЭКСОСМИТКЛАЙН ЭлЭлСи | Замещенные бициклические аза-гетероциклы и их аналоги в качестве модуляторов сиртуина |
AR085073A1 (es) * | 2012-01-11 | 2013-09-11 | Richmond Sa Com Ind Y Financiera Lab | Compuestos con actividad antibacteriana, un procedimiento para su obtencion y composiciones farmaceuticas que los comprenden |
AU2014372639A1 (en) * | 2013-12-23 | 2016-06-09 | Norgine B.V. | Benzene sulfonamides as CCR9 inhibitors |
AU2014372638A1 (en) | 2013-12-23 | 2016-06-16 | Norgine B.V. | Compounds useful as CCR9 modulators |
WO2015143652A1 (en) * | 2014-03-26 | 2015-10-01 | Merck Sharp & Dohme Corp. | TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF |
KR20210068597A (ko) * | 2018-10-30 | 2021-06-09 | 크로노스 바이오, 인코포레이티드 | Cdk9 활성을 조절하기 위한 화합물, 조성물 및 방법 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE792533A (fr) * | 1971-12-09 | 1973-06-08 | Int Chem & Nuclear Corp | Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation |
US3925385A (en) * | 1972-04-20 | 1975-12-09 | Icn Pharmaceuticals | 6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines |
JPS6157587A (ja) * | 1984-08-29 | 1986-03-24 | Shionogi & Co Ltd | 縮合複素環誘導体および抗潰瘍剤 |
US4950585A (en) * | 1987-08-18 | 1990-08-21 | Konica Corporation | Coupler for photographic use |
JP2585462B2 (ja) * | 1989-10-25 | 1997-02-26 | 株式会社大塚製薬工場 | ピラゾロ[1,5―a]ピリミジン誘導体 |
US5688949A (en) * | 1991-04-22 | 1997-11-18 | Otsuka Pharmaceutical Factory, Inc. | Pyrazolo 1,5-A!pyrimidine derivatives and anti-inflammatory agent containing the same |
ATE194977T1 (de) * | 1991-09-06 | 2000-08-15 | Yoshitomi Pharmaceutical | 4-amino(alkyl)cyclohexan-1-carboxamidverbindung n und ihre verwendung |
US5571813A (en) * | 1993-06-10 | 1996-11-05 | Beiersdorf-Lilly Gmbh | Fused pyrimidine compounds and their use as pharmaceuticals |
-
1995
- 1995-06-05 DE DE69523864T patent/DE69523864T2/de not_active Expired - Fee Related
- 1995-06-05 CN CN95190760A patent/CN1046730C/zh not_active Expired - Fee Related
- 1995-06-05 DK DK95920260T patent/DK0714898T3/da active
- 1995-06-05 US US08/602,824 patent/US5707997A/en not_active Expired - Lifetime
- 1995-06-05 EP EP95920260A patent/EP0714898B1/en not_active Expired - Lifetime
- 1995-06-05 WO PCT/JP1995/001104 patent/WO1995035298A1/ja active IP Right Grant
- 1995-06-05 AU AU25765/95A patent/AU680370B2/en not_active Ceased
- 1995-06-05 ES ES95920260T patent/ES2164153T3/es not_active Expired - Lifetime
- 1995-06-05 PT PT95920260T patent/PT714898E/pt unknown
- 1995-06-05 AT AT95920260T patent/ATE208776T1/de not_active IP Right Cessation
- 1995-06-05 CA CA002169719A patent/CA2169719C/en not_active Expired - Fee Related
- 1995-06-05 KR KR1019960700854A patent/KR100315837B1/ko not_active IP Right Cessation
- 1995-06-16 TW TW084106201A patent/TW307767B/zh active
Also Published As
Publication number | Publication date |
---|---|
DE69523864D1 (de) | 2001-12-20 |
CN1046730C (zh) | 1999-11-24 |
EP0714898B1 (en) | 2001-11-14 |
KR100315837B1 (ko) | 2002-02-28 |
ATE208776T1 (de) | 2001-11-15 |
DE69523864T2 (de) | 2002-06-13 |
US5707997A (en) | 1998-01-13 |
TW307767B (pt) | 1997-06-11 |
ES2164153T3 (es) | 2002-02-16 |
CA2169719C (en) | 2002-04-16 |
AU680370B2 (en) | 1997-07-24 |
CN1131948A (zh) | 1996-09-25 |
WO1995035298A1 (fr) | 1995-12-28 |
EP0714898A4 (en) | 1997-04-02 |
EP0714898A1 (en) | 1996-06-05 |
AU2576595A (en) | 1996-01-15 |
KR960703919A (ko) | 1996-08-31 |
CA2169719A1 (en) | 1995-12-28 |
DK0714898T3 (da) | 2002-03-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT714898E (pt) | Derivado de pirazolo¬1,5-a|pirimidina | |
EP0945452A4 (en) | SUGAR COMPOSITIONS, GELLING AGENTS, GELLING AGENT COMPOSITIONS, METHODS OF PREPARING SAME, AND GEL COMPOSITIONS | |
CA2239245A1 (en) | N-substituted dioxothiazolidylbenzamide derivatives and process for producing the same | |
EP0955293A4 (en) | NEW DURATION DERIVATIVES | |
DE69434136D1 (de) | Dolastatin-derivate | |
DK0826688T3 (da) | Pentacykliske forbindelser | |
DK0918776T3 (da) | Totalsyntese af antitumor acylfulvener | |
MY141488A (en) | Hydroximic acid derivatives, processes for their preparation, and compositions comprising them | |
NO971384D0 (no) | Pyrimidinylpyrazol-derivat | |
DE69530501D1 (de) | Chinolinderivat | |
AU5387990A (en) | Thiazole derivatives | |
PT852226E (pt) | Derivados de pirimidina | |
ES2159729T3 (es) | Derivados de pirazolo(1,5-a)pirimidina. | |
AU5034690A (en) | Carboxylimino benzothiazole derivatives | |
WO1996022286A3 (en) | Arthropodicidal oxazines and thiazines |