PT3240895T - Composições e métodos para glicosilação de proteínas - Google Patents

Composições e métodos para glicosilação de proteínas

Info

Publication number
PT3240895T
PT3240895T PT158229484T PT15822948T PT3240895T PT 3240895 T PT3240895 T PT 3240895T PT 158229484 T PT158229484 T PT 158229484T PT 15822948 T PT15822948 T PT 15822948T PT 3240895 T PT3240895 T PT 3240895T
Authority
PT
Portugal
Prior art keywords
compositions
methods
protein glycosylation
glycosylation
protein
Prior art date
Application number
PT158229484T
Other languages
English (en)
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of PT3240895T publication Critical patent/PT3240895T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1081Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
PT158229484T 2014-12-30 2015-12-24 Composições e métodos para glicosilação de proteínas PT3240895T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462097975P 2014-12-30 2014-12-30
US201462098071P 2014-12-30 2014-12-30

Publications (1)

Publication Number Publication Date
PT3240895T true PT3240895T (pt) 2022-03-02

Family

ID=55080101

Family Applications (1)

Application Number Title Priority Date Filing Date
PT158229484T PT3240895T (pt) 2014-12-30 2015-12-24 Composições e métodos para glicosilação de proteínas

Country Status (18)

Country Link
US (3) US10150952B2 (pt)
EP (2) EP3240895B1 (pt)
JP (1) JP6850724B2 (pt)
CN (1) CN107614679A (pt)
BE (1) BE1022998B1 (pt)
BR (1) BR112017014031B1 (pt)
CA (1) CA2971653C (pt)
CY (1) CY1125392T1 (pt)
DK (1) DK3240895T3 (pt)
ES (1) ES2907211T3 (pt)
HR (1) HRP20220500T1 (pt)
HU (1) HUE057726T2 (pt)
LT (1) LT3240895T (pt)
MX (1) MX2017008817A (pt)
PL (1) PL3240895T3 (pt)
PT (1) PT3240895T (pt)
SI (1) SI3240895T1 (pt)
WO (2) WO2016107818A1 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014111516A1 (en) 2013-01-17 2014-07-24 Arsanis Biosciences Gmbh Mdr e. coli specific antibody
FI3110441T3 (fi) 2014-02-24 2024-05-06 Glaxosmithkline Biologicals Sa Uusi polysakkaridi ja sen käyttöjä
PT3240895T (pt) 2014-12-30 2022-03-02 Glaxosmithkline Biologicals Sa Composições e métodos para glicosilação de proteínas
US10265391B2 (en) 2015-02-26 2019-04-23 Vaxnewmo Llc Acinetobacter O-oligosaccharyltransferases and uses thereof
TWI715617B (zh) 2015-08-24 2021-01-11 比利時商葛蘭素史密斯克藍生物品公司 對抗腸道外病原性大腸桿菌之免疫保護之方法及組合物
AR109621A1 (es) 2016-10-24 2018-12-26 Janssen Pharmaceuticals Inc Formulaciones de vacunas contra glucoconjugados de expec
GB201704117D0 (en) * 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide
GB201721576D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa Hla antigens and glycoconjugates thereof
GB201721582D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa S aureus antigens and immunogenic compositions
US11932670B2 (en) 2018-06-16 2024-03-19 Vaxnewmo Llc Glycosylated ComP pilin variants, methods of making and uses thereof
US20220088211A1 (en) * 2018-12-21 2022-03-24 Vaxnewmo Llc O-linked glycosylation recognition motifs
MX2021011445A (es) * 2019-03-18 2021-10-13 Janssen Pharmaceuticals Inc Bioconjugados de polisacaridos de antigenos o de e. coli, metodos de produccion y metodos de uso de los mismos.
JP2022525773A (ja) 2019-03-18 2022-05-19 ヤンセン ファーマシューティカルズ,インコーポレーテッド 大腸菌o抗原多糖のバイオコンジュゲートを製造する方法、その組成物およびその使用方法
EP3770269A1 (en) 2019-07-23 2021-01-27 GlaxoSmithKline Biologicals S.A. Quantification of bioconjugate glycosylation
JP2022543678A (ja) * 2019-08-09 2022-10-13 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 変異型pglbオリゴサッカリルトランスフェラーゼ酵素
EP3777884A1 (en) 2019-08-15 2021-02-17 GlaxoSmithKline Biologicals S.A. Immunogenic composition
CN110910960B (zh) * 2019-11-30 2022-07-08 浙江天科高新技术发展有限公司 一种鲍曼不动杆菌分子血清型快速分析方法
CN115803087A (zh) 2020-09-17 2023-03-14 杨森制药公司 多价疫苗组合物及其用途
WO2022171679A2 (en) * 2021-02-11 2022-08-18 Glaxosmithkline Biologicals Sa Protein
MX2023011697A (es) 2021-04-01 2023-10-19 Janssen Pharmaceuticals Inc Produccion de bioconjugados o18 de e. coli.
WO2023118033A1 (en) 2021-12-22 2023-06-29 Glaxosmithkline Biologicals Sa Vaccine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1888761B1 (en) * 2005-05-11 2010-09-29 ETH Zurich Recombinant n-glycosylated proteins from procaryotic cells
CN101960017B (zh) * 2008-01-03 2017-06-09 康乃尔研究基金会有限公司 原核生物中的糖基化蛋白表达
EP3427749A1 (en) * 2008-02-20 2019-01-16 GlaxoSmithKline Biologicals SA Bioconjugates made from recombinant n-glycosylated proteins from procaryotic cells
TR201803015T4 (tr) * 2009-11-19 2018-03-21 Glaxosmithkline Biologicals Sa Prokaryotik hücrelerde immünojenik polisakaridler üreten biyosentetik sistem.
EP3281639B1 (en) 2010-05-06 2020-11-11 GlaxoSmithKline Biologicals S.A. Capsular gram-positive bacteria bioconjugate vaccines
US11193154B2 (en) * 2011-11-04 2021-12-07 Cornell University Prokaryote-based cell-free system for the synthesis of glycoproteins
US9931392B2 (en) * 2013-01-18 2018-04-03 London School Of Hygiene And Tropical Medicine Glycosylation method
PT3240895T (pt) 2014-12-30 2022-03-02 Glaxosmithkline Biologicals Sa Composições e métodos para glicosilação de proteínas
GB201704117D0 (en) * 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide

Also Published As

Publication number Publication date
WO2016107819A1 (en) 2016-07-07
ES2907211T3 (es) 2022-04-22
US20180002679A1 (en) 2018-01-04
CN107614679A (zh) 2018-01-19
JP2018500912A (ja) 2018-01-18
CY1125392T1 (el) 2024-02-16
JP6850724B2 (ja) 2021-03-31
US20200181586A1 (en) 2020-06-11
WO2016107818A1 (en) 2016-07-07
SI3240895T1 (sl) 2022-04-29
MX2017008817A (es) 2017-10-24
EP3240895A1 (en) 2017-11-08
PL3240895T3 (pl) 2022-05-02
CA2971653C (en) 2024-06-11
CA2971653A1 (en) 2016-07-07
US10150952B2 (en) 2018-12-11
BE1022998A1 (fr) 2016-10-28
HUE057726T2 (hu) 2022-06-28
BR112017014031B1 (pt) 2023-11-07
EP3240895B1 (en) 2022-01-26
BR112017014031A2 (pt) 2018-01-16
US20190078064A1 (en) 2019-03-14
BE1022998B1 (fr) 2016-10-28
LT3240895T (lt) 2022-04-11
WO2016107818A8 (en) 2017-08-31
HRP20220500T1 (hr) 2022-06-10
US11015177B2 (en) 2021-05-25
US10577592B2 (en) 2020-03-03
DK3240895T3 (da) 2022-04-11
EP4043561A1 (en) 2022-08-17

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