PT2872620T - Derivação e autorrenovação de células lsl+ e usos das mesmas - Google Patents

Derivação e autorrenovação de células lsl+ e usos das mesmas

Info

Publication number
PT2872620T
PT2872620T PT137533634T PT13753363T PT2872620T PT 2872620 T PT2872620 T PT 2872620T PT 137533634 T PT137533634 T PT 137533634T PT 13753363 T PT13753363 T PT 13753363T PT 2872620 T PT2872620 T PT 2872620T
Authority
PT
Portugal
Prior art keywords
isi1
renewal
derivation
cells
self
Prior art date
Application number
PT137533634T
Other languages
English (en)
Original Assignee
Isletone Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isletone Ab filed Critical Isletone Ab
Publication of PT2872620T publication Critical patent/PT2872620T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/415—Wnt; Frizzeled
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT137533634T 2012-07-12 2013-07-11 Derivação e autorrenovação de células lsl+ e usos das mesmas PT2872620T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261670640P 2012-07-12 2012-07-12

Publications (1)

Publication Number Publication Date
PT2872620T true PT2872620T (pt) 2020-03-03

Family

ID=49036626

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137533634T PT2872620T (pt) 2012-07-12 2013-07-11 Derivação e autorrenovação de células lsl+ e usos das mesmas

Country Status (10)

Country Link
US (2) US10226487B2 (pt)
EP (1) EP2872620B1 (pt)
AU (1) AU2013287307A1 (pt)
CA (1) CA2917743A1 (pt)
DK (1) DK2872620T3 (pt)
ES (1) ES2777932T3 (pt)
PL (1) PL2872620T3 (pt)
PT (1) PT2872620T (pt)
SG (1) SG11201500139SA (pt)
WO (1) WO2014011095A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2872620T (pt) 2012-07-12 2020-03-03 Isletone Ab Derivação e autorrenovação de células lsl+ e usos das mesmas
EP3546568A3 (en) * 2013-07-02 2019-10-23 National University of Singapore Differentiation of pluripotent stem cells and cardiac progenitor cells into striated cardiomyocyte fibers using laminins ln-511, ln-521 and ln-221
US10683486B2 (en) 2015-10-30 2020-06-16 Biolamina Ab Methods for producing hepatocytes
JP6989591B2 (ja) * 2016-04-26 2022-01-05 アイレットワン・アーベー 多能性細胞の誘導及び自己再生並びにその使用
AU2022260542A1 (en) * 2021-04-23 2023-10-19 Avulotion Ab Extracellular vesicles from mesenchymal stromal cells for treatment of diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005046596A2 (en) * 2003-11-04 2005-05-26 University Of Maryland Baltimore Stem cell culture medium and method of using said medium and the cells
US9101590B2 (en) 2005-07-29 2015-08-11 Yale University Defined culture conditions of human embryonic stem cells
US8951799B2 (en) * 2007-01-04 2015-02-10 Biolamina Ab Composition and method for enabling proliferation of pluripotent stem cells
WO2008094597A2 (en) * 2007-01-30 2008-08-07 University Of Georgia Research Foundation, Inc. Early mesoderm cells, a stable population of mesendoderm cells that has utility for generation of endoderm and mesoderm lineages and multipotent migratory cells (mmc)
US20110305672A1 (en) * 2008-07-25 2011-12-15 University Of Georgia Research Foundation, Inc. COMPOSITIONS FOR MESODERM DERIVED ISL1+ MULTIPOTENT CELLS (IMPs), EPICARDIAL PROGENITOR CELLS (EPCs) AND MULTIPOTENT CD56C CELLS (C56Cs) AND METHODS OF PRODUCING AND USING SAME
CN102165058B (zh) 2008-07-25 2015-07-01 佐治亚大学研究基金会 中胚层来源的ISL 1+多潜能细胞(IMPs)的组合物、心外膜祖细胞(EPCs)和多潜能CXCR4+CD56+细胞(C56Cs)及其使用方法
US10240124B2 (en) * 2011-09-22 2019-03-26 Biolamina Ab Cell culture substrate comprising a laminin and a cadherin
EP3282009A1 (en) * 2012-04-20 2018-02-14 Biolamina AB Maintenance of differentiated cells with laminins
PT2872620T (pt) 2012-07-12 2020-03-03 Isletone Ab Derivação e autorrenovação de células lsl+ e usos das mesmas
EP3546568A3 (en) * 2013-07-02 2019-10-23 National University of Singapore Differentiation of pluripotent stem cells and cardiac progenitor cells into striated cardiomyocyte fibers using laminins ln-511, ln-521 and ln-221
HUE041518T2 (hu) * 2015-02-20 2019-05-28 Inst Nat Sante Rech Med Laminin alkalmazása pluripotens sejtek hepatocita sejtvonalhoz tartozó sejtekké történõ differenciálódásához

Also Published As

Publication number Publication date
US11607429B2 (en) 2023-03-21
SG11201500139SA (en) 2015-02-27
US10226487B2 (en) 2019-03-12
EP2872620B1 (en) 2020-01-15
US20150164958A1 (en) 2015-06-18
AU2013287307A1 (en) 2015-02-26
PL2872620T3 (pl) 2020-08-24
WO2014011095A1 (en) 2014-01-16
US20190290700A1 (en) 2019-09-26
ES2777932T3 (es) 2020-08-06
CA2917743A1 (en) 2014-01-16
DK2872620T3 (da) 2020-03-16
EP2872620A1 (en) 2015-05-20

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