PT2751081T - Forma polimórfica de pitavastatina cálcica - Google Patents

Forma polimórfica de pitavastatina cálcica

Info

Publication number
PT2751081T
PT2751081T PT127567501T PT12756750T PT2751081T PT 2751081 T PT2751081 T PT 2751081T PT 127567501 T PT127567501 T PT 127567501T PT 12756750 T PT12756750 T PT 12756750T PT 2751081 T PT2751081 T PT 2751081T
Authority
PT
Portugal
Prior art keywords
polymorphic form
pitavastatin calcium
pitavastatin
calcium
polymorphic
Prior art date
Application number
PT127567501T
Other languages
English (en)
Inventor
Trost Sabina
Kljajic Alen
Pecavar Anica
Zupet Rok
Original Assignee
D O O Farma Grs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by D O O Farma Grs filed Critical D O O Farma Grs
Publication of PT2751081T publication Critical patent/PT2751081T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0036—Crystallisation on to a bed of product crystals; Seeding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B01D9/0054—Use of anti-solvent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT127567501T 2011-09-12 2012-09-12 Forma polimórfica de pitavastatina cálcica PT2751081T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI201100359 2011-09-12

Publications (1)

Publication Number Publication Date
PT2751081T true PT2751081T (pt) 2017-04-04

Family

ID=46829784

Family Applications (1)

Application Number Title Priority Date Filing Date
PT127567501T PT2751081T (pt) 2011-09-12 2012-09-12 Forma polimórfica de pitavastatina cálcica

Country Status (6)

Country Link
EP (1) EP2751081B1 (pt)
EA (1) EA024991B1 (pt)
ES (1) ES2620968T3 (pt)
PT (1) PT2751081T (pt)
SI (1) SI2751081T1 (pt)
WO (1) WO2013037838A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014154856A1 (en) * 2013-03-29 2014-10-02 Dsm Sinochem Pharmaceuticals Netherlands B.V. Amine salts of pravastatin and rosuvastatin
EP3058113B1 (en) 2013-10-14 2020-12-02 Orbotech Ltd. Lift printing of multi-composition material structures
EP3207772B1 (en) 2014-10-19 2024-04-17 Orbotech Ltd. Lift printing of conductive traces onto a semiconductor substrate
US10633758B2 (en) 2015-01-19 2020-04-28 Orbotech Ltd. Printing of three-dimensional metal structures with a sacrificial support
CN108349120B (zh) 2015-11-22 2020-06-23 奥博泰克有限公司 打印的三维结构的表面性质控制
CN107115306B (zh) * 2017-04-17 2019-09-13 浙江京新药业股份有限公司 一种含匹伐他汀钙的药物组合物及其制备方法
TW201901887A (zh) 2017-05-24 2019-01-01 以色列商奧寶科技股份有限公司 於未事先圖樣化基板上電器互連電路元件

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1336714C (en) 1987-08-20 1995-08-15 Yoshihiro Fujikawa Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis
JP3528186B2 (ja) 1991-06-24 2004-05-17 日産化学工業株式会社 光学活性キノリンメバロン酸のジアステレオマー塩
PL376557A1 (pl) 2003-02-12 2006-01-09 Ciba Specialty Chemicals Holding Inc. Postacie krystaliczne pitawastatyny wapnia
TWI328006B (en) * 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production
WO2007132482A2 (en) * 2006-05-17 2007-11-22 Manne Satyanarayana Reddy Novel process for the preparation of pitavastatin and its pharmaceutically acceptable salts
CN101195603A (zh) * 2007-11-21 2008-06-11 重庆医药工业研究院有限责任公司 一种匹伐他汀钙的新晶型及其制备方法
WO2010089770A2 (en) 2009-01-19 2010-08-12 Msn Laboratories Limited Improved process for the preparation of highly pure (3r,5s)-7-[2-cyclopropyl-4-(4-fluorophenyl) quinolin-3-yl]-3,5-dihydroxy-6(e)-heptenoic acid and pharmaceutically acceptable salts thereof
KR20100125124A (ko) * 2009-05-20 2010-11-30 미래파인켐 주식회사 피타바스타틴 헤미칼슘염의 신규한 결정형 및 그의 제조방법
JP2013516459A (ja) 2010-01-20 2013-05-13 カディラ・ヘルスケア・リミテッド ピタバスタチン及び医薬として許容可能なそれらの塩の製造方法
KR101134021B1 (ko) * 2010-02-24 2012-04-05 주식회사 메디켐코리아 새로운 중간체를 이용하는 피타바스타틴 헤미칼슘의 신규한 제조방법
EP3178812A1 (en) * 2010-11-12 2017-06-14 Hetero Research Foundation Novel polymorphs of pitavastatin calcium

Also Published As

Publication number Publication date
EA201490578A1 (ru) 2015-01-30
WO2013037838A1 (en) 2013-03-21
EA024991B1 (ru) 2016-11-30
SI2751081T1 (sl) 2017-05-31
ES2620968T3 (es) 2017-06-30
EP2751081B1 (en) 2017-01-04
EP2751081A1 (en) 2014-07-09

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